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Pseudoprogression (PsP) is an imitation of true tumor progression (TTP) in patients with glioblastoma multiform (GBM). Differentiating them is a challenging and time-consuming task for radiologists. Although deep neural networks can…

Tissues and Organs · Quantitative Biology 2019-02-27 Xiaoming Liu , Michael D. Chan , Xiaobo Zhou , Xiaohua Qian

Accurate detection and segmentation of diffuse large B-cell lymphoma (DLBCL) from PET images has important implications for estimation of total metabolic tumor volume, radiomics analysis, surgical intervention and radiotherapy. Manual…

Image and Video Processing · Electrical Eng. & Systems 2024-03-13 Shadab Ahamed , Natalia Dubljevic , Ingrid Bloise , Claire Gowdy , Patrick Martineau , Don Wilson , Carlos F. Uribe , Arman Rahmim , Fereshteh Yousefirizi

Glioma growth may be quantified with longitudinal image registration. However, the large mass-effects and tissue changes across images pose an added challenge. Here, we propose a longitudinal, learning-based, and groupwise registration…

Non-small cell lung cancer (NSCLC) is a serious disease and has a high recurrence rate after the surgery. Recently, many machine learning methods have been proposed for recurrence prediction. The methods using gene data have high prediction…

Computer Vision and Pattern Recognition · Computer Science 2021-04-30 Panyanat Aonpong , Yutaro Iwamoto , Xian-Hua Han , Lanfen Lin , Yen-Wei Chen

AIM To analyse the performance of a deep-learning (DL) algorithm currently deployed as diagnostic decision support software in two NHS Trusts used to identify normal chest x-rays in active clinical pathways. MATERIALS AND METHODS A DL…

Computer Vision and Pattern Recognition · Computer Science 2023-06-29 Jordan Smith , Tom Naunton Morgan , Paul Williams , Qaiser Malik , Simon Rasalingham

Gliomas are the most frequent primary brain tumors in adults. Glioma change detection aims at finding the relevant parts of the image that change over time. Although Deep Learning (DL) shows promising performances in similar change…

Computer Vision and Pattern Recognition · Computer Science 2023-01-27 Tommaso Di Noto , Meritxell Bach Cuadra , Chirine Atat , Eduardo Gamito Teiga , Monika Hegi , Andreas Hottinger , Patric Hagmann , Jonas Richiardi

The introduction of lung cancer screening programs will produce an unprecedented amount of chest CT scans in the near future, which radiologists will have to read in order to decide on a patient follow-up strategy. According to the current…

In recent years, Deep Learning (DL) has shown promising results in conducting AI tasks such as computer vision and image segmentation. Specifically, Convolutional Neural Network (CNN) models in DL have been applied to prevention,detection,…

Image and Video Processing · Electrical Eng. & Systems 2019-11-19 Ahmed Awad Albishri , Syed Jawad Hussain Shah , Anthony Schmiedler , Seung Suk Kang , Yugyung Lee

Improving patient outcomes depends on the prompt and accurate diagnosis of brain tumors, but manual MRI scan analysis is still time-consuming and unreliable. Although deep learning has shown promise, many of the models that are now in use…

Image and Video Processing · Electrical Eng. & Systems 2026-05-14 Md Fahimul Kabir Chowdhury , Jannatul Ferdous

Automatic segmentation of brain glioma from multimodal MRI scans plays a key role in clinical trials and practice. Unfortunately, manual segmentation is very challenging, time-consuming, costly, and often inaccurate despite human expertise…

Image and Video Processing · Electrical Eng. & Systems 2020-12-08 Minh H. Vu , Tufve Nyholm , Tommy Löfstedt

Glioblastoma Multiforme (GBM) is an aggressive form of malignant brain tumor with a generally poor prognosis. Treatment usually includes a mix of surgical resection, radiation therapy, and akylating chemotherapy but, even with these…

Medical Physics · Physics 2024-01-11 Erich Schmitz , Yunhui Guo , Jing Wang

The time-consuming task of manual segmentation challenges routine systematic quantification of disease burden. Convolutional neural networks (CNNs) hold significant promise to reliably identify locations and boundaries of tumors from PET…

Tumor heterogeneity is a challenge to designing effective and targeted therapies. Glioma-type identification depends on specific molecular and histological features, which are defined by the official WHO classification CNS. These guidelines…

Applications · Statistics 2023-05-23 Roberta Coletti , Mónica L. Mendonça , Susana Vinga , Marta B. Lopes

Background and Purpose: Pediatric low-grade glioma (pLGG) is the most common type of brain tumor in children, and identification of molecular markers for pLGG is crucial for successful treatment planning. Convolutional Neural Network (CNN)…

Computer Vision and Pattern Recognition · Computer Science 2023-10-26 Khashayar Namdar , Matthias W. Wagner , Kareem Kudus , Cynthia Hawkins , Uri Tabori , Brigit Ertl-Wagner , Farzad Khalvati

Accurate prediction of cardiovascular disease (CVD) risk is crucial for healthcare institutions. This study addresses the growing prevalence of diabetes and its strong link to heart disease by proposing an efficient CVD risk prediction…

Machine Learning · Computer Science 2025-11-10 Esha Chowdhury

Despite great advances, molecular cancer pathology is often limited to the use of a small number of biomarkers rather than the whole transcriptome, partly due to computational challenges. Here, we introduce a novel architecture of Deep…

Machine Learning · Statistics 2019-08-14 Behrooz Azarkhalili , Ali Saberi , Hamidreza Chitsaz , Ali Sharifi-Zarchi

A glioma is a malignant brain tumor that seriously affects cognitive functions and lowers patients' life quality. Segmentation of brain glioma is challenging because of interclass ambiguities in tumor regions. Recently, deep learning…

Image and Video Processing · Electrical Eng. & Systems 2022-11-02 Yiming Yao , Peisheng Qian , Ziyuan Zhao , Zeng Zeng

Background and Objective: Non-invasively predicting the risk of cancer metastasis before surgery plays an essential role in determining optimal treatment methods for cancer patients (including who can benefit from neoadjuvant chemotherapy).…

Patient-derived cells (PDC) mouse xenografts are increasingly important tools in glioblastoma (GBM) research, essential to investigate case-specific growth patterns and treatment responses. Despite the central role of xenograft models in…

Quantitative Methods · Quantitative Biology 2024-03-15 Adam A. Malik , Cecilia Krona , Soumi Kundu , Philip Gerlee , Sven Nelander

Glioblastoma is a common brain malignancy that tends to occur in older adults and is almost always lethal. The effectiveness of chemotherapy, being the standard treatment for most cancer types, can be improved if a particular genetic…

Image and Video Processing · Electrical Eng. & Systems 2022-03-01 Numan Saeed , Shahad Hardan , Kudaibergen Abutalip , Mohammad Yaqub