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This contribution presents a parameter identification methodology for the accurate and fast estimation of model parameters in a pseudo-two-dimensional (P2D) battery model. The methodology consists of three key elements. First, the data for…

Systems and Control · Electrical Eng. & Systems 2025-07-21 L. D. Couto , K. Haghverdi , F. Guo , K. Trad , G. Mulder

Motivated by risk assessment of coastal flooding, we consider time-consuming simulators with a spatial output. The aim is to perform sensitivity analysis (SA), quantifying the influence of input parameters on the output. There are three…

Bayesian parameter estimation provides a systematic approach to compare heavy ion collision models with measurements, leading to constraints on the properties of nuclear matter with proper accounting of experimental and theoretical…

Nuclear Theory · Physics 2023-05-31 Brandon Weiss , Jean-François Paquet , Steffen A. Bass

In the wake of the intense effort made for the experimental CILEX project, numerical simulation cam- paigns have been carried out in order to finalize the design of the facility and to identify optimal laser and plasma parameters. These…

Computational Physics · Physics 2016-04-20 Arnaud Beck , Jacob Trier Frederiksen , Julien Dérouillat

A main barrier for the deployment of AI radiomic systems in clinical routine is their drop in performance under heterogeneous multicentre acquisition protocols. This work presents a performance-oriented framework for quantifying scan…

Artificial Intelligence · Computer Science 2026-05-15 D. Gil , I. Sanchez , C. Sanchez

Physical models of biological systems can become difficult to interpret when they have a large number of parameters. But the models themselves actually depend on (i.e. are sensitive to) only a subset of those parameters. Rigorously…

Biological Physics · Physics 2018-11-27 Chieh-Ting Hsu , Gary J. Brouhard , Paul François

In this paper we develop a new method for numerically approximating sensitivities in parameter-dependent ordinary differential equations (ODEs). Our approach, intended for situations where the standard forward and adjoint sensitivity…

Numerical Analysis · Mathematics 2024-07-12 Olivia Eriksson , Andrei Kramer , Federica Milinanni , Pierre Nyquist

Zero-dimensional cardiovascular models provide a computationally efficient framework for studying global hemodynamic behavior, yet the influence of model complexity on parameter sensitivity remains insufficiently understood. This work…

Medical Physics · Physics 2026-01-05 Pranav Kumar Sasikumar

Variance based global sensitivity analysis measures the relevance of inputs to a single output using Sobol' indices. This paper extends the definition in a natural way to multiple outputs, directly measuring the relevance of inputs to the…

Statistics Theory · Mathematics 2025-03-25 Robert A. Milton , Solomon F. Brown

We consider the problem of parameter estimation in dynamic systems described by ordinary differential equations. A review of the existing literature emphasizes the need for deterministic global optimization methods due to the nonconvex…

Optimization and Control · Mathematics 2025-06-16 M. Fernández de Dios , Ángel M. González-Rueda , Julio R. Banga , Julio González-Díaz , David R. Penas

Mathematical models of thrombosis are currently used to study clinical scenarios of pathological thrombus formation. Most of these models involve inherent uncertainties that must be assessed to increase the confidence in model predictions…

Quantitative Methods · Quantitative Biology 2021-07-02 Rodrigo Méndez Rojano , Mansur Zhussupbekov , James F. Antaki , Didier Lucor

The material removal rates during milling operations are affected by the selection of the cutting depth and spindle speed. Poor selection of these parameters can result in chatter or suboptimal material removal rates. Stability Lobe…

Numerical Analysis · Mathematics 2024-07-16 M. Hashemitaheri , T. T. Le , T. Khan , H. Cherukuri

For multiple reasons -- such as avoiding overtraining from one data set or because of having received numerical estimates for some parameters in a model from an alternative source -- it is sometimes useful to divide a model's parameters…

Methodology · Statistics 2024-06-26 Yunrong Wan

Decision circuits have been developed to perform efficient evaluation of influence diagrams [Bhattacharjya and Shachter, 2007], building on the advances in arithmetic circuits for belief network inference [Darwiche,2003]. In the process of…

Artificial Intelligence · Computer Science 2012-06-18 Debarun Bhattacharjya , Ross D. Shachter

Sensitivity analysis is a process of computing sensitivity indices, which are certain measures of importance of parameters in influencing the outputs of mathematical models. Sensitivity indices computed in variance-based sensitivity…

Computation · Statistics 2013-10-04 Tomasz Badowski

High-fidelity simulations and physical experiments are essential for engineering analysis and design, yet their high cost often makes two critical tasks--global sensitivity analysis (GSA) and optimization--prohibitively expensive. This…

Machine Learning · Computer Science 2026-01-01 Bach Do , Nafeezat A. Ajenifuja , Taiwo A. Adebiyi , Ruda Zhang

Reliable predictions from systems biology models require knowing whether parameters can be estimated from available data, and with what certainty. Identifiability analysis reveals whether parameters are learnable in principle (structural…

Background: Many mathematical models have now been employed across every area of systems biology. These models increasingly involve large numbers of unknown parameters, have complex structure which can result in substantial evaluation time…

Molecular Networks · Quantitative Biology 2018-01-15 Ian Vernon , Junli Liu , Michael Goldstein , James Rowe , Jen Topping , Keith Lindsey

Image recognition tasks typically use deep learning and require enormous processing power, thus relying on hardware accelerators like GPUs and FPGAs for fast, timely processing. Failure in real-time image recognition tasks can occur due to…

Machine Learning · Computer Science 2023-02-22 Nikolaos Louloudakis , Perry Gibson , José Cano , Ajitha Rajan

This paper tackles the challenge of parameter calibration in stochastic models, particularly in scenarios where the likelihood function is unavailable in an analytical form. We introduce a gradient-based simulated parameter estimation…

Machine Learning · Statistics 2025-03-25 Zehao Li , Yijie Peng