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Medical imaging systems are often evaluated and optimized via objective, or task-specific, measures of image quality (IQ) that quantify the performance of an observer on a specific clinically-relevant task. The performance of the Bayesian…

Signal Processing · Electrical Eng. & Systems 2023-04-04 Weimin Zhou , Umberto Villa , Mark A. Anastasio

The ideal observer (IO) sets an upper performance limit among all observers and has been advocated for assessing and optimizing imaging systems. For general joint detection and estimation (detection-estimation) tasks, estimation ROC (EROC)…

Signal Processing · Electrical Eng. & Systems 2021-12-03 Kaiyan Li , Weimin Zhou , Hua Li , Mark A. Anastasio

Medical imaging systems are commonly assessed and optimized by use of objective measures of image quality (IQ). The Ideal Observer (IO) performance has been advocated to provide a figure-of-merit for use in assessing and optimizing imaging…

Signal Processing · Electrical Eng. & Systems 2020-07-16 Weimin Zhou , Hua Li , Mark A. Anastasio

It is widely accepted that optimization of medical imaging system performance should be guided by task-based measures of image quality (IQ). Task-based measures of IQ quantify the ability of an observer to perform a specific task such as…

Signal Processing · Electrical Eng. & Systems 2019-05-17 Weimin Zhou , Hua Li , Mark A. Anastasio

In medical imaging, it is widely recognized that image quality should be objectively evaluated based on performance in clinical tasks. To evaluate performance in signal-detection tasks, the ideal observer (IO) is optimal but also…

Medical Physics · Physics 2022-03-09 Md Ashequr Rahman , Zitong Yu , Abhinav K. Jha

Generative artificial intelligence (AI) has made unprecedented advances in vision language models over the past two years. During the generative process, new samples (images) are generated from an unknown high-dimensional distribution.…

Graphics · Computer Science 2025-10-13 Gurprit Singh , Wenzel Jakob

Statistical signal processing applications usually require the estimation of some parameters of interest given a set of observed data. These estimates are typically obtained either by solving a multi-variate optimization problem, as in the…

Computation · Statistics 2021-07-27 D. Luengo , L. Martino , M. Bugallo , V. Elvira , S. Särkkä

Markov chain Monte Carlo (MCMC) is a powerful tool for sampling from complex probability distributions. Despite its versatility, MCMC often suffers from strong autocorrelation and the negative sign problem, leading to slowing down the…

Statistical Mechanics · Physics 2024-12-05 Synge Todo

Monte Carlo (MC) methods are widely used for Bayesian inference and optimization in statistics, signal processing and machine learning. A well-known class of MC methods are Markov Chain Monte Carlo (MCMC) algorithms. In order to foster…

Computation · Statistics 2016-09-27 L. Martino , V. Elvira , D. Luengo , J. Corander , F. Louzada

Medical imaging systems are commonly assessed and optimized by the use of objective measures of image quality (IQ). The performance of the ideal observer (IO) acting on imaging measurements has long been advocated as a figure-of-merit to…

Medical Physics · Physics 2025-01-17 Kaiyan Li , Prabhat Kc , Hua Li , Kyle J. Myers , Mark A. Anastasio , Rongping Zeng

Markov Chain Monte Carlo (MCMC) methods sample from unnormalized probability distributions and offer guarantees of exact sampling. However, in the continuous case, unfavorable geometry of the target distribution can greatly limit the…

Machine Learning · Statistics 2020-10-09 Zengyi Li , Yubei Chen , Friedrich T. Sommer

Generative adversarial networks (GANs) have emerged as a powerful tool for generating high-fidelity data. However, the main bottleneck of existing approaches is the lack of supervision on the generator training, which often results in…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Baoren Xiao , Hao Ni , Weixin Yang

In the context of solving inverse problems for physics applications within a Bayesian framework, we present a new approach, Markov Chain Generative Adversarial Neural Networks (MCGANs), to alleviate the computational costs associated with…

Numerical Analysis · Mathematics 2022-09-08 Nikolaj T. Mücke , Benjamin Sanderse , Sander Bohté , Cornelis W. Oosterlee

Accurately detecting symbols transmitted over multiple-input multiple-output (MIMO) wireless channels is crucial in realizing the benefits of MIMO techniques. However, optimal MIMO detection is associated with a complexity that grows…

Signal Processing · Electrical Eng. & Systems 2024-10-28 Xingyu Zhou , Le Liang , Jing Zhang , Chao-Kai Wen , Shi Jin

Purpose: To objectively assess new medical imaging technologies via computer-simulations, it is important to account for the variability in the ensemble of objects to be imaged. This source of variability can be described by stochastic…

Image and Video Processing · Electrical Eng. & Systems 2022-03-01 Weimin Zhou , Sayantan Bhadra , Frank J. Brooks , Hua Li , Mark A. Anastasio

Task-based assessment of image quality (IQ) is critically important for the design and optimization of medical imaging systems. Ideal observers, including the Bayesian Ideal Observer (IO) and the ideal linear observer, i.e., the Hotelling…

Image and Video Processing · Electrical Eng. & Systems 2026-05-29 Weimin Zhou

The discrete nature of transmitted symbols poses challenges for achieving optimal detection in multiple-input multiple-output (MIMO) systems associated with a large number of antennas. Recently, the combination of two powerful machine…

Signal Processing · Electrical Eng. & Systems 2024-12-11 Xingyu Zhou , Le Liang , Jing Zhang , Chao-Kai Wen , Shi Jin

The Pseudo-Marginal (PM) algorithm is a popular Markov chain Monte Carlo (MCMC) method used to sample from a target distribution when its density is inaccessible, but can be estimated with a non-negative unbiased estimator. Its performance…

Computation · Statistics 2025-09-30 Sarra Abaoubida , Mylène Bédard , Florian Maire

New and existing methods for generating, and especially detecting, deepfakes are investigated and compared on the simple problem of authenticating coin flip data. Importantly, an alternative approach to deepfake generation and detection,…

Applications · Statistics 2026-03-16 Michael A. Kouritzin , Ian Zhang , Jyoti Bhadana , Seoyeon Park

We focus on generative autoencoders, such as variational or adversarial autoencoders, which jointly learn a generative model alongside an inference model. Generative autoencoders are those which are trained to softly enforce a prior on the…

Machine Learning · Computer Science 2017-01-13 Antonia Creswell , Kai Arulkumaran , Anil Anthony Bharath
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