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In the clinical diagnosis and treatment of brain tumors, manual image reading consumes a lot of energy and time. In recent years, the automatic tumor classification technology based on deep learning has entered people's field of vision.…

Image and Video Processing · Electrical Eng. & Systems 2021-04-07 Yuhao Zhang , Shuhang Wang , Haoxiang Wu , Kejia Hu , Shufan Ji

Parameters in mathematical models for glioblastoma multiforme (GBM) tumour growth are highly patient specific. Here we aim to estimate parameters in a Cahn-Hilliard type diffuse interface model in an optimised way using model order…

Numerical Analysis · Mathematics 2023-07-19 Abramo Agosti , Pasquale Ciarletta , Harald Garcke , Michael Hinze

Gliomas are brain tumours with a high mortality rate. There are various grades and sub-types of this tumour, and the treatment procedure varies accordingly. Clinicians and oncologists diagnose and categorise these tumours based on visual…

Image and Video Processing · Electrical Eng. & Systems 2020-11-12 Azam Hamidinekoo , Tomasz Pieciak , Maryam Afzali , Otar Akanyeti , Yinyin Yuan

Purpose; The purpose of this study is to classify glial tumors into grade II, III and IV categories noninvasively by application of machine learning to multi-modal MRI features in comparison with volumetric analysis. Methods; We…

Image and Video Processing · Electrical Eng. & Systems 2022-08-16 Sevcan Turk , Kaya Oguz , Mehmet Orman , Emre Caliskan , Yesim Ertan , Erkin Ozgiray , Taner Akalin , Ashok Srinivasan , Omer Kitis

Biophysical modeling, particularly involving partial differential equations (PDEs), offers significant potential for tailoring disease treatment protocols to individual patients. However, the inverse problem-solving aspect of these models…

Non-invasive techniques such as magnetic resonance imaging (MRI) are widely employed in brain tumor diagnostics. However, manual segmentation of brain tumors from 3D MRI volumes is a time-consuming task that requires trained expert…

Image and Video Processing · Electrical Eng. & Systems 2020-12-24 Benjamin Maas , Erfan Zabeh , Soroush Arabshahi

Modeling tumor growth accurately is essential for understanding cancer progression and informing treatment strategies. To estimate the parameters in the tumor growth model described by a nonlinear PDE, we adopt Physics-Informed Neural…

Analysis of PDEs · Mathematics 2025-11-21 Liu Liu , Yifei Wang , Qinyu Xu , Xiaoqian Xu

The ability to estimate how a tumor might evolve in the future could have tremendous clinical benefits, from improved treatment decisions to better dose distribution in radiation therapy. Recent work has approached the glioma growth…

Multimodal deep learning has improved prognostic accuracy for brain tumours by integrating histopathology and genomic data, yet the contribution of volumetric MRI within unified survival frameworks remains unexplored. This pilot study…

Computer Vision and Pattern Recognition · Computer Science 2026-04-01 Iain Swift , JingHua Ye

Radiomic models have been shown to outperform clinical data for outcome prediction in glioblastoma (GBM). However, clinical implementation is limited by lack of parameters standardization. We aimed to compare nine machine learning…

Objective: Brain metastases (BMs) are common in cancer patients and determining the primary tumor site is crucial for effective treatment. This study aims to predict the primary tumor site from BM MRI data using radiomic features and…

Machine Learning · Computer Science 2024-07-09 Hamidreza Sadeghsalehi

Tumor growth from a single transformed cancer cell up to a clinically apparent mass spans many spatial and temporal orders of magnitude. Implementation of cellular automata simulations of such tumor growth can be straightforward but…

Quantitative Methods · Quantitative Biology 2013-09-25 Jan Poleszczuk , Heiko Enderling

Brain tumor segmentation is highly contributive in diagnosing and treatment planning. The manual brain tumor delineation is a time-consuming and tedious task and varies depending on the radiologists skill. Automated brain tumor segmentation…

Medical Physics · Physics 2022-03-08 Farzaneh Dehghani , Alireza Karimian , Hossein Arabi

Tumor treating fields (TTFields) is an FDA approved therapy for the treatment of Gliobastoma Multiform (GBM) and currently being investigated for additional tumor types. TTFields are delivered to the tumor through the placement of…

Image and Video Processing · Electrical Eng. & Systems 2019-06-27 Reuben R Shamir , Zeev Bomzon

Efforts to utilize growing volumes of clinical imaging data to generate tumor evaluations continue to require significant manual data wrangling owing to the data heterogeneity. Here, we propose an artificial intelligence-based solution for…

MRI analysis takes central position in brain tumor diagnosis and treatment, thus it's precise evaluation is crucially important. However, it's 3D nature imposes several challenges, so the analysis is often performed on 2D projections that…

Computer Vision and Pattern Recognition · Computer Science 2018-10-10 Dmitry Lachinov , Evgeny Vasiliev , Vadim Turlapov

The diagnosis of brain cancer relies heavily on medical imaging techniques, with MRI being the most commonly used. It is necessary to perform automatic segmentation of brain tumors on MRI images. This project intends to build an MRI…

Image and Video Processing · Electrical Eng. & Systems 2024-06-28 Yuxiang Hu , Haowei Yang , Ting Xu , Shuyao He , Jiajie Yuan , Haozhang Deng

This paper deals with the cellular biological network analysis of the tumor-growth model, consisting of multiple spaces and time scales. In this paper, we present a model in graph simulation using ABM for tumor growth. In particular, we…

Multiagent Systems · Computer Science 2019-09-05 Ghazal Tashakor , Remo Suppi

Brain tumors, particularly glioblastoma, continue to challenge medical diagnostics and treatments globally. This paper explores the application of deep learning to multi-modality magnetic resonance imaging (MRI) data for enhanced brain…

Image and Video Processing · Electrical Eng. & Systems 2023-08-15 Chiranjeewee Prasad Koirala , Sovesh Mohapatra , Advait Gosai , Gottfried Schlaug

Glioblastoma is one of the most aggressive and common brain tumors, with a median survival of 10-15 months. Predicting Overall Survival (OS) is critical for personalizing treatment strategies and aligning clinical decisions with patient…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Yin Lin , Riccardo Barbieri , Domenico Aquino , Giuseppe Lauria , Marina Grisoli , Elena De Momi , Alberto Redaelli , Simona Ferrante