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Related papers: Endo-microscopy beyond the Abbe and Nyquist limits

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Despite all the success with developing super-resolution imaging techniques, the Abbe limit poses a severe fundamental restriction on the resolution of far-field imaging systems based on diffraction of light. Imaging with contact…

Essentially, the idea of improving the resolution of a given imaging system is to enhance its information capacity represented usually by the temporal-bandwidth (or, spatial-spectrum) product. This letter introduces the concept of…

Optics · Physics 2014-03-21 Lianlin Li , Fang Li , Tiejun Cui

Endoscopic imaging is essential for real-time visualization of internal organs, yet conventional systems remain bulky, complex, and expensive due to their reliance on large, multi-element optical components. This limits their accessibility…

Recently, it was discovered that microsphere can generate super-resolution focusing beyond diffraction limit. This has led to the development of an exciting super-resolution imaging technique -microsphere nanoscopy- that features a record…

Optics · Physics 2021-08-26 Zengbo Wang

The photo-kinetics of fluorescent molecules have enabled the circumvention of far-field optical diffraction-limit. Despite its enormous potential, the necessity to label the sample may adversely influence the delicate biology under…

Fluorescence microscopy is widely used in biological imaging, however scattering from tissues strongly limits its applicability to a shallow depth. In this work we adapt a methodology inspired from stellar speckle interferometry, and…

A major open challenge in neuroscience is the ability to measure and perturb neural activity in vivo from well-defined neural sub-populations at cellular resolution anywhere in the brain. However, limitations posed by scattering and…

Biological Physics · Physics 2017-11-10 Shay Ohayon , Antonio Miguel Caravaca-Aguirre , Rafael Piestun , James J. DiCarlo

Much more image details can be resolved by improving the system's imaging resolution and enhancing the resolution beyond the system's Rayleigh diffraction limit is generally called super-resolution. By combining the sparse prior property of…

Quantum Physics · Physics 2015-03-20 Wenlin Gong , Shensheng Han

Imaging of scenes using light or other wave phenomena is subject to the diffraction limit. The spatial profile of a wave propagating between a scene and the imaging system is distorted by diffraction resulting in a loss of resolution that…

Image and Video Processing · Electrical Eng. & Systems 2020-07-20 Ji Hyun Nam , Andreas Velten

Optical microscopy has so far been restricted to superficial layers, leaving many important biological questions unanswered. Random scattering causes the ballistic focus, which is conventionally used for image formation, to decay…

Optics · Physics 2012-08-28 Ke Si , Reto Fiolka , Meng Cui

Superresolution fluorescence microscopy techniques beat the diffraction limit, enabling ultra-high resolution imaging in biological physics and nanoscience. In all cases that have been studied experimentally, the resolution scales inversely…

Optics · Physics 2012-10-10 Alexander Small

Fluorescence microscopy is a critical tool across various disciplines, from materials science to biomedical research, yet it is limited by the diffraction limit of resolution. Advanced super-resolution techniques such as localization…

Breaking the diffraction limit in optical imaging is crucial for resolving subwavelength details in a wide range of applications, where superoscillatory imaging and subtraction imaging are two common strategies for surpassing conventional…

Optical microscopy is one of the oldest scientific instruments that is still used in forefront research. Ernst Abbe's nineteenth century formulation of the resolution limit in microscopy let generations of scientists believe that optical…

Optics · Physics 2015-06-09 Siegfried Weisenburger , Vahid Sandoghdar

Flexible fiber-optic endoscopes provide a minimally-invasive solution for imaging at depths beyond the reach of conventional microscopes. Current endoscopes require focusing and/or scanning mechanisms at the distal end, which limit…

First discovered by Ernest Abbe in 1873, the resolution limit of a far-field microscope is considered determined by the numerical aperture and wavelength of light, approximately $\lambda$/2NA. With the advent of modern fluorescence…

Optics · Physics 2023-08-02 Yilun Li , Fang Huang

The manifestation of the wave nature of light through diffraction imposes limits on the resolution of optical imaging. For over a century, the Abbe-Rayleigh criterion has been utilized to assess the spatial resolution limits of optical…

Near-field scanning optical microscopy has been an indispensable tool for designing, characterizing and understanding the functionalities of diverse nanoscale photonic devices. As the advances in fabrication technology have driven the…

Super-resolution effects in optical and fluorescence biological systems are analyzed and their relations with uncertainty relations are discussed. Super-resolutions obtained in the optical systems, including especially NSOM, SIM and…

Optics · Physics 2015-06-12 Yacob Ben-Aryeh

Super-resolution microscopy normally requiring complex and cumbersome optics is not applicable for in situ imaging through a narrow channel. Here, we demonstrate single hair-thin multimode fiber (MMF) endoscope (less than 250 ${\mu}m$) for…