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Full Field Digital Mammograms (FFDMs) and Digital Breast Tomosynthesis (DBT) are the two most widely used imaging modalities for breast cancer screening. Although DBT has increased cancer detection compared to FFDM, its widespread adoption…

Computer Vision and Pattern Recognition · Computer Science 2024-08-19 Umang Sharma , Jungkyu Park , Laura Heacock , Sumit Chopra , Krzysztof Geras

Computer-aided detection systems based on deep learning have shown good performance in breast cancer detection. However, high-density breasts show poorer detection performance since dense tissues can mask or even simulate masses. Therefore,…

Image and Video Processing · Electrical Eng. & Systems 2023-01-25 Lidia Garrucho , Kaisar Kushibar , Richard Osuala , Oliver Diaz , Alessandro Catanese , Javier del Riego , Maciej Bobowicz , Fredrik Strand , Laura Igual , Karim Lekadir

Purpose: To develop a Breast Imaging Reporting and Data System (BI-RADS) breast density deep learning (DL) model in a multi-site setting for synthetic two-dimensional mammography (SM) images derived from digital breast tomosynthesis exams…

Although digital breast tomosynthesis (DBT) improves diagnostic performance over full-field digital mammography (FFDM), false-positive recalls remain a concern in breast cancer screening. We developed a multi-modal artificial intelligence…

Image and Video Processing · Electrical Eng. & Systems 2025-04-14 Jungkyu Park , Jan Witowski , Yanqi Xu , Hari Trivedi , Judy Gichoya , Beatrice Brown-Mulry , Malte Westerhoff , Linda Moy , Laura Heacock , Alana Lewin , Krzysztof J. Geras

The rapid development of deep learning, a family of machine learning techniques, has spurred much interest in its application to medical imaging problems. Here, we develop a deep learning algorithm that can accurately detect breast cancer…

Computer Vision and Pattern Recognition · Computer Science 2019-10-08 Li Shen , Laurie R. Margolies , Joseph H. Rothstein , Eugene Fluder , Russell B. McBride , Weiva Sieh

Digital Breast Tomosynthesis (DBT) enhances finding visibility for breast cancer detection by providing volumetric information that reduces the impact of overlapping tissues; however, limited annotated data has constrained the development…

Computer Vision and Pattern Recognition · Computer Science 2025-11-14 Yen Nhi Truong Vu , Dan Guo , Sripad Joshi , Harshit Kumar , Jason Su , Thomas Paul Matthews

As early detection of breast cancer strongly favors successful therapeutic outcomes, there is major commercial interest in optimizing breast cancer screening. However, current risk prediction models achieve modest performance and do not…

Image and Video Processing · Electrical Eng. & Systems 2025-09-03 Manon A. Dorster , Felix J. Dorfner , Mason C. Cleveland , Melisa S. Guelen , Jay Patel , Dania Daye , Jean-Philippe Thiran , Albert E. Kim , Christopher P. Bridge

The two-dimensional nature of mammography makes estimation of the overall breast density challenging, and estimation of the true patient-specific radiation dose impossible. Digital breast tomosynthesis (DBT), a pseudo-3D technique, is now…

Breast cancer screening is one of the most common radiological tasks with over 39 million exams performed each year. While breast cancer screening has been one of the most studied medical imaging applications of artificial intelligence, the…

Image and Video Processing · Electrical Eng. & Systems 2022-11-22 Mateusz Buda , Ashirbani Saha , Ruth Walsh , Sujata Ghate , Nianyi Li , Albert Święcicki , Joseph Y. Lo , Maciej A. Mazurowski

Breast cancer remains a global challenge, causing over 1 million deaths globally in 2018. To achieve earlier breast cancer detection, screening x-ray mammography is recommended by health organizations worldwide and has been estimated to…

Digital Breast Tomosynthesis (DBT) is a widely used medical imaging modality for breast cancer screening and diagnosis, offering higher spatial resolution and greater detail through its 3D-like breast volume imaging capability. However, the…

Image and Video Processing · Electrical Eng. & Systems 2024-03-21 Yuexi Du , Regina J. Hooley , John Lewin , Nicha C. Dvornek

Purpose: The goal of this study is to develop a novel deep learning (DL) based reconstruction framework to improve the digital breast tomosynthesis (DBT) imaging performance. Methods: In this work, the DIR-DBTnet is developed for DBT image…

Medical Physics · Physics 2021-06-09 Ting Su , Xiaolei Deng , Zhenwei Wang , Jiecheng Yang , Jianwei Chen , Hairong Zheng , Dong Liang , Yongshuai Ge

Purpose: To develop and evaluate the accuracy of a multi-view deep learning approach to the analysis of high-resolution synthetic mammograms from digital breast tomosynthesis screening cases, and to assess the effect on accuracy of image…

Image and Video Processing · Electrical Eng. & Systems 2020-09-29 Saeed Seyyedi , Margaret J. Wong , Debra M. Ikeda , Curtis P. Langlotz

Digital Breast Tomosynthesis (DBT) provides an insight into the fine details of normal fibroglandular tissues and abnormal lesions by reconstructing a pseudo-3D image of the breast. In this respect, DBT overcomes a major limitation of…

Computer Vision and Pattern Recognition · Computer Science 2013-07-24 Guang Yang , John H. Hipwell , David J. Hawkes , Simon R. Arridge

Digital breast tomosynthesis (DBT) is an emerging modality for breast imaging. A typical tomosynthesis image is reconstructed from projection data acquired at a limited number of views over a limited angular range. In general, the…

Medical Physics · Physics 2009-08-19 I. Reiser , J. Bian , R. M. Nishikawa , E. Y. Sidky , X. Pan

Breast density estimation is one of the key tasks in recognizing individuals predisposed to breast cancer. It is often challenging because of low contrast and fluctuations in mammograms' fatty tissue background. Most of the time, the breast…

Image and Video Processing · Electrical Eng. & Systems 2022-10-11 Vikash Gupta , Mutlu Demirer , Robert W. Maxwell , Richard D. White , Barbaros Selnur Erdal

Automated methods for breast cancer detection have focused on 2D mammography and have largely ignored 3D digital breast tomosynthesis (DBT), which is frequently used in clinical practice. The two key challenges in developing automated…

Computer Vision and Pattern Recognition · Computer Science 2020-02-28 Yu Zhang , Xiaoqin Wang , Hunter Blanton , Gongbo Liang , Xin Xing , Nathan Jacobs

Reconstruction of digital breast tomosynthesis is a challenging problem due to the limited angle data available in such systems. Due to memory limitations, deep learning-based methods can help improve these reconstructions, but can not…

Medical Physics · Physics 2020-09-04 Koen Michielsen , Nikita Moriakov , Jonas Teuwen , Ioannis Sechopoulos

Data limitation is a significant challenge in applying deep learning to medical images. Recently, the diffusion probabilistic model (DPM) has shown the potential to generate high-quality images by converting Gaussian random noise into…

Computer Vision and Pattern Recognition · Computer Science 2024-08-26 Sepehr Salem Ghahfarokhi , Tyrell To , Julie Jorns , Tina Yen , Bing Yu , Dong Hye Ye

Computer-aided detection or decision support systems aim to improve breast cancer screening programs by helping radiologists to evaluate digital mammography (DM) exams. Commonly such methods proceed in two steps: selection of candidate…

Computer Vision and Pattern Recognition · Computer Science 2018-03-09 Timothy de Moor , Alejandro Rodriguez-Ruiz , Albert Gubern Mérida , Ritse Mann , Jonas Teuwen
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