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We consider integro-differential models describing the evolution of a population structured by a quantitative trait. Individuals interact competitively, creating a strong selection pressure on the population. On the other hand, mutations…

Analysis of PDEs · Mathematics 2012-03-20 Pierre-Emmanuel Jabin

Predicting the adaptation of populations to a changing environment is crucial to assess the impact of human activities on biodiversity. Many theoretical studies have tackled this issue by modeling the evolution of quantitative traits…

Analysis of PDEs · Mathematics 2022-06-28 Jimmy Garnier , O Cotto , T Bourgeron , E Bouin , T Lepoutre , O Ronce , V Calvez

The nested Kingman coalescent describes the ancestral tree of a population undergoing neutral evolution at the level of individuals and at the level of species, simultaneously. We study the speed at which the number of lineages descends…

Probability · Mathematics 2018-03-28 Airam Blancas Benítez , Tim Rogers , Jason Schweinsberg , Arno Siri-Jégousse

Kingman's coalescent is a random tree that arises from classical population genetic models such as the Moran model. The individuals alive in these models correspond to the leaves in the tree and the following two laws of large numbers…

Probability · Mathematics 2014-06-24 Andrej Depperschmidt , Peter Pfaffelhuber , Annika Scheuringer

We present a two-species population model in a well-mixed environment where the dynamics involves, in addition to birth and death, changes due to environmental factors and inter-species interactions. The novel dynamical components are…

Biological Physics · Physics 2020-09-17 J. J. Dong , J. D. Russo , K. Sampson

We discuss stochastic dynamics of populations of individuals playing games. Our models possess two evolutionarily stable strategies: an efficient one, where a population is in a state with the maximal payoff (fitness) and a risk-dominant…

Populations and Evolution · Quantitative Biology 2007-05-23 Jacek Miekisz

Environment plays a fundamental role in the competition for resources, and hence in the evolution of populations. Here, we study a well-mixed, finite population consisting of two strains competing for the limited resources provided by an…

Populations and Evolution · Quantitative Biology 2017-10-16 Karl Wienand , Erwin Frey , Mauro Mobilia

In subdivided populations, migration acts together with selection and genetic drift and determines their evolution. Building up on a recently proposed method, which hinges on the emergence of a time scale separation between local and global…

Populations and Evolution · Quantitative Biology 2015-03-24 Pierangelo Lombardo , Andrea Gambassi , Luca Dall'Asta

Competition between individuals drives the evolution of whole species. Although the fittest individuals survive the longest and produce the most offspring, in some circumstances the resulting species may not be optimally fit. Here, using…

Populations and Evolution · Quantitative Biology 2015-09-24 Tim Rogers , Alan J. McKane

Cancer progression is an evolutionary process that is driven by mutation and selection in a population of tumor cells. We discuss mathematical models of cancer progression, starting from traditional multistage theory. Each stage is…

Populations and Evolution · Quantitative Biology 2011-08-31 Moritz Gerstung , Niko Beerenwinkel

We discuss the population dynamics with selection and random diffusion, keeping the total population constant, in a fitness landscape associated with Constraint Satisfaction, a paradigm for difficult optimization problems. We obtain a phase…

Populations and Evolution · Quantitative Biology 2016-11-23 Tommaso Brotto , Guy Bunin , Jorge Kurchan

We consider a population evolving due to mutation, selection and recombination, where selection includes single-locus terms (additive fitness) and two-loci terms (pairwise epistatic fitness). We further consider the problem of inferring…

Populations and Evolution · Quantitative Biology 2021-09-01 Hong-Li Zeng , Eugenio Mauri , Vito Dichio , Simona Cocco , Remi Monasson , Erik Aurell

The dynamics of adaptation is difficult to predict because it is highly stochastic even in large populations. The uncertainty emerges from number fluctuations, called genetic drift, arising in the small number of particularly fit…

Populations and Evolution · Quantitative Biology 2015-06-30 Oskar Hallatschek , Lukas Geyrhofer

We consider an approximating sequence of interacting population models with branching, mutation and competition. Each individual is characterized by its trait and the traits of its ancestors. Birth- and death-events happen at exponential…

Probability · Mathematics 2014-12-08 Sandra Kliem

How fast does a population evolve from one fitness peak to another? We study the dynamics of evolving, asexually reproducing populations in which a certain number of mutations jointly confer a fitness advantage. We consider the time until a…

Populations and Evolution · Quantitative Biology 2010-03-31 Chaitanya S. Gokhale , Yoh Iwasa , Martin A. Nowak , Arne Traulsen

We consider a model of a population with fixed size $N$, which is subjected to an unlimited supply of beneficial mutations at a constant rate $\mu_N$. Individuals with $k$ beneficial mutations have the fitness $(1+s_N)^k$. Each individual…

Probability · Mathematics 2024-12-30 Nantawat Udomchatpitak , Jason Schweinsberg

This study elaborates some examples of a simple evolutionary stochastic rate process where the population rate of change depends on the distribution of properties--so different cohorts change at different rates. We investigate the effect on…

Populations and Evolution · Quantitative Biology 2010-01-26 C. T. J. Dodson

We consider a model of a population in which individuals are sampled from different species. The Yule-Kingman nested coalescent describes the genealogy of the sample when each species merges with another randomly chosen species with a…

Probability · Mathematics 2023-12-20 Toni Gui

In evolutionary games the fitness of individuals is not constant but depends on the relative abundance of the various strategies in the population. Here we study general games among n strategies in populations of large but finite size. We…

Populations and Evolution · Quantitative Biology 2009-05-16 Tibor Antal , Arne Traulsen , Hisashi Ohtsuki , Corina E. Tarnita , Martin A. Nowak

Many biological populations exhibit diversity in their strategy for survival and reproduction in a given environment, and microbes are an example. We explore the fate of different strategies under sustained environmental change by…

Populations and Evolution · Quantitative Biology 2025-09-24 Ruixi Huang , David Waxman
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