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Missing data are inevitable in longitudinal studies. Traditional methods, such as the full information maximum likelihood (FIML), are commonly used to handle ignorable missing data. However, they may lead to biased model estimation due to…

Applications · Statistics 2024-01-01 Dandan Tang , Xin Tong

In this paper, we develop a novel efficient and robust nonparametric regression estimator under a framework of feedforward neural network. There are several interesting characteristics for the proposed estimator. First, the loss function is…

Methodology · Statistics 2023-09-25 Xuancheng Wang , Ling Zhou , Huazhen Lin

Variational inference (VI) is a specific type of approximate Bayesian inference that approximates an intractable posterior distribution with a tractable one. VI casts the inference problem as an optimization problem, more specifically, the…

Machine Learning · Computer Science 2022-12-20 Felix Leibfried

Mendelian randomization (MR) is an instrumental variable (IV) approach to infer causal relationships between exposures and outcomes with genome-wide association studies (GWAS) summary data. However, the multivariable inverse-variance…

Methodology · Statistics 2024-02-13 Yihe Yang , Noah Lorincz-Comi , Xiaofeng Zhu

The Importance Weighted Auto Encoder (IWAE) objective has been shown to improve the training of generative models over the standard Variational Auto Encoder (VAE) objective. Here, we derive importance weighted extensions to AVB and AAE.…

Machine Learning · Computer Science 2019-10-24 Daniel Jiwoong Im , Sridhama Prakhya , Jinyao Yan , Srinivas Turaga , Kristin Branson

The Matrix Multiplicative Weight Update (MMWU) is a seminal online learning algorithm with numerous applications. Applied to the matrix version of the Learning from Expert Advice (LEA) problem on the $d$-dimensional spectraplex, it is well…

Machine Learning · Computer Science 2025-09-12 Weiyuan Gong , Tongyang Li , Xinzhao Wang , Zhiyu Zhang

Meta-learning allows an intelligent agent to leverage prior learning episodes as a basis for quickly improving performance on a novel task. Bayesian hierarchical modeling provides a theoretical framework for formalizing meta-learning as…

Machine Learning · Computer Science 2018-01-29 Erin Grant , Chelsea Finn , Sergey Levine , Trevor Darrell , Thomas Griffiths

In variational inference (VI), the marginal log-likelihood is estimated using the standard evidence lower bound (ELBO), or improved versions as the importance weighted ELBO (IWELBO). We propose the multiple importance sampling ELBO…

Machine Learning · Computer Science 2022-02-23 Oskar Kviman , Harald Melin , Hazal Koptagel , Víctor Elvira , Jens Lagergren

Reading comprehension is a key for individual success, yet the assessment of question difficulty remains challenging due to the extensive human annotation and large-scale testing required by traditional methods such as linguistic analysis…

Computation and Language · Computer Science 2025-02-26 Yoshee Jain , John Hollander , Amber He , Sunny Tang , Liang Zhang , John Sabatini

We propose a new method for the Maximum Likelihood Estimator (MLE) of nonlinear mixed effects models when the variance matrix of Gaussian random effects has a prescribed pattern of zeros (PPZ). The method consists in coupling the recently…

Methodology · Statistics 2009-02-11 Djalil Chafai , Didier Concordet

We propose a variational autoencoder (VAE) approach for parameter estimation in nonlinear mixed-effects models based on ordinary differential equations (NLME-ODEs) using longitudinal data from multiple subjects. In moderate dimensions,…

Methodology · Statistics 2026-02-11 Zhe Li , Mélanie Prague , Rodolphe Thiébaut , Quentin Clairon

The maximum likelihood amplitude estimation algorithm (MLAE) is a practical solution to the quantum amplitude estimation problem with Heisenberg limit error convergence. We improve MLAE by using random depths to avoid the so-called critical…

Quantum Physics · Physics 2023-11-20 Xi Lu , Hongwei Lin

We study inverse reinforcement learning (IRL) and imitation learning (IM), the problems of recovering a reward or policy function from expert's demonstrated trajectories. We propose a new way to improve the learning process by adding a…

Machine Learning · Computer Science 2022-08-23 The Viet Bui , Tien Mai , Patrick Jaillet

A major line of contemporary research on complex networks is based on the development of statistical models that specify the local motifs associated with macro-structural properties observed in actual networks. This statistical approach…

Methodology · Statistics 2018-08-02 Maksym Byshkin , Alex Stivala , Antonietta Mira , Garry Robins , Alessandro Lomi

State inference and parameter learning in sequential models can be successfully performed with approximation techniques that maximize the evidence lower bound to the marginal log-likelihood of the data distribution. These methods may be…

Machine Learning · Computer Science 2026-03-10 Helena Calatrava , Ricardo Augusto Borsoi , Tales Imbiriba , Pau Closas

Estimating item difficulty through field-testing is often resource-intensive and time-consuming. As such, there is strong motivation to develop methods that can predict item difficulty at scale using only the item content. Large Language…

Computers and Society · Computer Science 2026-03-10 Pooya Razavi , Sonya Powers

Estimators derived from a divergence criterion such as $\varphi-$divergences are generally more robust than the maximum likelihood ones. We are interested in particular in the so-called MD$\varphi$DE, an estimator built using a dual…

Computation · Statistics 2016-06-14 Diaa Al Mohamad , Michel Broniatowski

General state-space models (SSMs) are widely used in statistical machine learning and are among the most classical generative models for sequential time-series data. SSMs, comprising latent Markovian states, can be subjected to variational…

Machine Learning · Statistics 2024-11-05 Alessandro Mastrototaro , Mathias Müller , Jimmy Olsson

High-dimensional and sparse (HiDS) matrices are omnipresent in a variety of big data-related applications. Latent factor analysis (LFA) is a typical representation learning method that extracts useful yet latent knowledge from HiDS matrices…

Machine Learning · Computer Science 2022-04-19 Di Wu , Peng Zhang , Yi He , Xin Luo

Variational autoencoders (VAEs) are popular likelihood-based generative models which can be efficiently trained by maximizing an Evidence Lower Bound (ELBO). There has been much progress in improving the expressiveness of the variational…

Machine Learning · Statistics 2023-08-29 Marcel Hirt , Vasileios Kreouzis , Petros Dellaportas