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In real-world clinical practice, overlooking unanticipated findings can result in serious consequences. However, supervised learning, which is the foundation for the current success of deep learning, only encourages models to identify…

Anomaly detection (AD) plays a pivotal role across diverse domains, including cybersecurity, finance, healthcare, and industrial manufacturing, by identifying unexpected patterns that deviate from established norms in real-world data.…

Machine Learning · Computer Science 2025-06-12 Yang Liu , Jing Liu , Chengfang Li , Rui Xi , Wenchao Li , Liang Cao , Jin Wang , Laurence T. Yang , Junsong Yuan , Wei Zhou

We propose a method that performs anomaly detection and localisation within heterogeneous data using a pairwise undirected mixed graphical model. The data are a mixture of categorical and quantitative variables, and the model is learned…

Machine Learning · Statistics 2016-07-21 Romain Laby , François Roueff , Alexandre Gramfort

Imaging in clinical routine is subject to changing scanner protocols, hardware, or policies in a typically heterogeneous set of acquisition hardware. Accuracy and reliability of deep learning models suffer from those changes as data and…

Machine Learning · Computer Science 2021-06-08 Matthias Perkonigg , Johannes Hofmanninger , Georg Langs

Health monitoring is important for maintaining reliable information and communications technology (ICT) systems. Anomaly detection methods based on machine learning, which train a model for describing "normality" are promising for…

Networking and Internet Architecture · Computer Science 2020-03-25 Kengo Tajiri , Yasuhiro Ikeda , Yuusuke Nakano , Keishiro Watanabe

Deep generative models are challenging the classical methods in the field of anomaly detection nowadays. Every new method provides evidence of outperforming its predecessors, often with contradictory results. The objective of this…

Machine Learning · Computer Science 2021-06-09 Vít Škvára , Jan Franců , Matěj Zorek , Tomáš Pevný , Václav Šmídl

In the anomaly detection field, the scarcity of anomalous samples has directed the current research emphasis towards unsupervised anomaly detection. While these unsupervised anomaly detection methods offer convenience, they also overlook…

Information Retrieval · Computer Science 2023-11-15 Shunfeng Wang , Yueyang Li , Haichi Luo , Chenyang Bi

This paper studies the problem of detecting anomalous graphs using a machine learning model trained on only normal graphs, which has many applications in molecule, biology, and social network data analysis. We present a self-discriminative…

Machine Learning · Computer Science 2023-10-11 Jinyu Cai , Yunhe Zhang , Jicong Fan

Automated anomaly detection from medical images, such as MRIs and X-rays, can significantly reduce human effort in disease diagnosis. Owing to the complexity of modeling anomalies and the high cost of manual annotation by domain experts…

Image and Video Processing · Electrical Eng. & Systems 2022-09-07 Md Mahfuzur Rahman Siddiquee , Jay Shah , Teresa Wu , Catherine Chong , Todd Schwedt , Baoxin Li

Most of the existing methods for anomaly detection use only positive data to learn the data distribution, thus they usually need a pre-defined threshold at the detection stage to determine whether a test instance is an outlier.…

Machine Learning · Computer Science 2019-03-19 Kai Tian , Shuigeng Zhou , Jianping Fan , Jihong Guan

Anomaly inspection plays an important role in industrial manufacture. Existing anomaly inspection methods are limited in their performance due to insufficient anomaly data. Although anomaly generation methods have been proposed to augment…

Computer Vision and Pattern Recognition · Computer Science 2024-02-23 Teng Hu , Jiangning Zhang , Ran Yi , Yuzhen Du , Xu Chen , Liang Liu , Yabiao Wang , Chengjie Wang

Pathological anomalies exhibit diverse appearances in medical imaging, making it difficult to collect and annotate a representative amount of data required to train deep learning models in a supervised setting. Therefore, in this work, we…

Image and Video Processing · Electrical Eng. & Systems 2023-07-18 Mariana-Iuliana Georgescu

The emergence of tau PET imaging over the last decade has enabled Alzheimer's disease (AD) researchers to examine tau pathology in vivo and more effectively characterize the disease trajectories of AD. Current tau PET analysis methods,…

Image and Video Processing · Electrical Eng. & Systems 2025-12-16 Lujia Zhong , Shuo Huang , Jiaxin Yue , Jianwei Zhang , Zhiwei Deng , Wenhao Chi , Yonggang Shi

In recent years, anomaly detection has become an essential field in medical image analysis. Most current anomaly detection methods for medical images are based on image reconstruction. In this work, we propose a novel anomaly detection…

Computer Vision and Pattern Recognition · Computer Science 2023-01-20 Florentin Bieder , Julia Wolleb , Robin Sandkühler , Philippe C. Cattin

With the development of medical imaging technology, medical images have become an important basis for doctors to diagnose patients. The brain structure in the collected data is complicated, thence, doctors are required to spend plentiful…

Image and Video Processing · Electrical Eng. & Systems 2020-07-10 Nan Wang , Chengwei Chen , Yuan Xie , Lizhuang Ma

Statistical analysis of magnetic resonance imaging (MRI) can help radiologists to detect pathologies that are otherwise likely to be missed. Deep learning (DL) has shown promise in modeling complex spatial data for brain anomaly detection.…

Computer Vision and Pattern Recognition · Computer Science 2020-11-26 Victor Saase , Holger Wenz , Thomas Ganslandt , Christoph Groden , Máté E. Maros

With the rapid development of the Internet, various types of anomaly traffic are threatening network security. We consider the problem of anomaly network traffic detection and propose a three-stage anomaly detection framework using only…

Machine Learning · Computer Science 2024-03-19 Zhangxuan Dang , Yu Zheng , Xinglin Lin , Chunlei Peng , Qiuyu Chen , Xinbo Gao

Visual anomaly detection is common in several applications including medical screening and production quality check. Although a definition of the anomaly is an unknown trend in data, in many cases some hints or samples of the anomaly class…

Computer Vision and Pattern Recognition · Computer Science 2019-03-29 Daiki Kimura , Minori Narita , Asim Munawar , Ryuki Tachibana

The identification and quantification of markers in medical images is critical for diagnosis, prognosis and management of patients in clinical practice. Supervised- or weakly supervised training enables the detection of findings that are…

Unsupervised anomaly detection is a challenging task. Autoencoders (AEs) or generative models are often employed to model the data distribution of normal inputs and subsequently identify anomalous, out-of-distribution inputs by high…

Machine Learning · Computer Science 2025-06-12 Yalin Liao , Austin J. Brockmeier
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