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Based on photoacoustic effect, photoacoustic tomography is developing very fast in recent years, and becoming an important imaging tool for both preclinical and clinical studies. With enough ultrasound transducers placed around the…

Image and Video Processing · Electrical Eng. & Systems 2020-11-13 Jiadong Zhang , Hengrong Lan , Changchun Yang , Shanshan Guo , Feng Gao , Fei Gao

Photoacoustic (PA) imaging has been widely applied in both preclinical and clinical applications. With a significantly increasing number of data acquisition channels, fast and high-quality image reconstruction for real-time PA imaging is an…

Medical Physics · Physics 2024-08-20 Zijian Gao , Yuting Shen , Daohuai Jiang , Fengyu Liu , Feng Gao , Fei Gao

Photoacoustic tomography (PAT) is a hybrid medical imaging technique that offer high contrast and a high spatial resolution. One challenging mathematical problem associated with PAT is reconstructing the initial pressure of the wave…

Numerical Analysis · Mathematics 2024-07-16 Gyeongha Hwang , Gihyeon Jeon , Sunghwan Moon , Dabin Park

Quantitative photo-acoustic tomography (QPAT) seeks to reconstruct a distribution of optical attenuation coefficients inside a sample from a set of time series of pressure data that is measured outside the sample. The associated inverse…

Optimization and Control · Mathematics 2019-09-04 Ashkan Javaherian , Sean Holman

Photoacoustic image (PAI) quality improvement using a low frequency piezoelectric micromachined ultrasound transducer (PMUT) having the fundamental resonant frequency 1 MHz is being reported. Specifically, three different methods are…

Instrumentation and Detectors · Physics 2022-12-01 Kaustav Roy , Arijit Paramanik , Souradip Paul , Akshay Kalyan , Eshani Sarkar , Anuj Ashok , Rudra Pratap , M Suheshkumar Singh

Photoacoustic tomography (PAT) is a newly emerged imaging modality which enables both high optical contrast and acoustic depth of penetration. Reconstructing images of photoacoustic tomography from limited amount of senser data is among one…

Computer Vision and Pattern Recognition · Computer Science 2023-06-27 Shangqing Tong , Hengrong Lan , Liming Nie , Jianwen Luo , Fei Gao

Photoacoustic tomography (PAT) is a non-invasive imaging modality that requires recovering the initial data of the wave equation from certain measurements of the solution outside the object. In the standard PAT measurement setup, the used…

Analysis of PDEs · Mathematics 2021-12-07 Linh V. Nguyen , Markus Haltmeier , Richard Kowar , Ngoc Do

The photoacoustic tomography (PAT) is a hybrid modality that combines the optics and acoustics to obtain high resolution and high contrast imaging of heterogeneous media. In this work, our objective is to study the inverse problem in the…

Numerical Analysis · Mathematics 2021-05-26 Hongkai Zhao , Yimin Zhong

Biomedical photoacoustic tomography, which can provide high resolution 3D soft tissue images based on the optical absorption, has advanced to the stage at which translation from the laboratory to clinical settings is becoming possible. The…

Image and Video Processing · Electrical Eng. & Systems 2020-11-20 Andreas Hauptmann , Ben Cox

Combining dual-energy computed tomography (DECT) with positron emission tomography (PET) offers many potential clinical applications but typically requires expensive hardware upgrades or increases radiation doses on PET/CT scanners due to…

Medical Physics · Physics 2024-06-21 Siqi Li , Yansong Zhu , Benjamin A. Spencer , Guobao Wang

Accurate measurement of optical absorption coefficients from photoacoustic imaging (PAI) data would enable direct mapping of molecular concentrations, providing vital clinical insight. The ill-posed nature of the problem of absorption…

Image and Video Processing · Electrical Eng. & Systems 2023-06-13 Janek Gröhl , Thomas R. Else , Lina Hacker , Ellie V. Bunce , Paul W. Sweeney , Sarah E. Bohndiek

Photoacoustic microscopy (PAM) is an emerging imaging method combining light and sound. However, limited by the laser's repetition rate, state-of-the-art high-speed PAM technology often sacrifices spatial sampling density (i.e.,…

Image and Video Processing · Electrical Eng. & Systems 2021-04-09 Tri Vu , Anthony DiSpirito , Daiwei Li , Zixuan Zhang , Xiaoyi Zhu , Maomao Chen , Laiming Jiang , Dong Zhang , Jianwen Luo , Yu Shrike Zhang , Qifa Zhou , Roarke Horstmeyer , Junjie Yao

Photoacoustic tomography leverages ultrasound's deep tissue penetration to retrieve optical absorption contrast well beyond the optical diffusion limit. Conventional photoacoustic systems rely on externally delivered light and are therefore…

Optics · Physics 2026-01-06 David C. Garrett , Lihong V. Wang

Three-dimensional (3D) photoacoustic computed tomography (PACT) is a powerful noninvasive biomedical imaging modality that provides volumetric data for structural and functional assessment \textit{in vivo}. To maximize angular coverage and…

Medical Physics · Physics 2026-03-26 Wanqing Zhang , Hengyue Zhu , Yide Zhang

Purpose: Photoacoustic tomography (PAT) is a novel imaging technique that can spatially resolve both morphological and functional tissue properties, such as the vessel topology and tissue oxygenation. While this capacity makes PAT a…

We study the deep image prior (DIP) framework applied to photoacoustic tomography (PAT) as an unsupervised reconstruction approach to mitigate limited-view artifacts and noise commonly encountered in experimental settings. Efficient…

Image and Video Processing · Electrical Eng. & Systems 2026-04-22 Hanna Pulkkinen , Jenni Poimala , Leonid Kunyansky , Janek Gröhl , Andreas Hauptmann

Dual-energy computed tomography (DECT) has shown great potential and promising applications in advanced imaging fields for its capabilities of material decomposition. However, image reconstructions and decompositions under sparse views…

Medical Physics · Physics 2016-08-01 Lei Li , Ailong Cai , Linyuan Wang , Bin Yan , Hanming Zhang , Zhizhong Zheng , Wenkun Zhang , Wanli Lu , Guoen Hu

One primary technical challenge in photoacoustic microscopy (PAM) is the necessary compromise between spatial resolution and imaging speed. In this study, we propose a novel application of deep learning principles to reconstruct…

Image and Video Processing · Electrical Eng. & Systems 2020-06-02 Anthony DiSpirito , Daiwei Li , Tri Vu , Maomao Chen , Dong Zhang , Jianwen Luo , Roarke Horstmeyer , Junjie Yao

Deep learning algorithms achieve high classification accuracy at the expense of significant computation cost. To address this cost, a number of quantization schemes have been proposed - but most of these techniques focused on quantizing…

Computer Vision and Pattern Recognition · Computer Science 2018-07-18 Jungwook Choi , Zhuo Wang , Swagath Venkataramani , Pierce I-Jen Chuang , Vijayalakshmi Srinivasan , Kailash Gopalakrishnan

In this paper, we design a PXI-based, multi-channel data-acquisition system (DAS) mainly applicable to recording one-shot fast transient pulses in nuclear physics experiments. The system consists of one NI PXIe-1085 chassis, containing a…

Instrumentation and Detectors · Physics 2020-01-07 Yafei Du , Jun Wu , Chen Yuan , Haohan Yang , Chuanfei Zhang , Yinong Liu