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Morphological analysis of longitudinal MR images plays a key role in monitoring disease progression for prostate cancer patients, who are placed under an active surveillance program. In this paper, we describe a learning-based image…

Image and Video Processing · Electrical Eng. & Systems 2020-11-05 Qianye Yang , Yunguan Fu , Francesco Giganti , Nooshin Ghavami , Qingchao Chen , J. Alison Noble , Tom Vercauteren , Dean Barratt , Yipeng Hu

In recent years, spatial and spatio-temporal modeling have become an important area of research in many fields (epidemiology, environmental studies, disease mapping). In this work we propose different spatial models to study hospital…

Applications · Statistics 2010-06-21 Erik A. Sauleau , Valentina Mameli , Monica Musio

Background and Objective: Bladder cancer is a common malignant urinary carcinoma, with muscle-invasive and non-muscle-invasive as its two major subtypes. This paper aims to achieve automated bladder cancer invasiveness localization and…

Computer Vision and Pattern Recognition · Computer Science 2023-02-23 Yu Ren , Guoli Wang , Pingping Wang , Kunmeng Liu , Quanjin Liu , Hongfu Sun , Xiang Li , Benzheng Wei

A statistical volumetric model, showing the probability map of localized prostate cancer within the host anatomical structure, has been developed from 90 optically-imaged surgical specimens. This master model permits an accurate…

Quantitative Methods · Quantitative Biology 2014-09-16 Liang Zhao , Jianhua Xuan , Yue Wang

Diabetes prevalence is on the rise in the UK, and for public health strategy, estimation of relative disease risk and subsequent mapping is important. We consider an application to London data on diabetes prevalence and mortality. In order…

Applications · Statistics 2020-12-08 Marco Gramatica , Peter Congdon , Silvia Liverani

Prostate radiotherapy is a well established curative oncology modality, which in future will use Magnetic Resonance Imaging (MRI)-based radiotherapy for daily adaptive radiotherapy target definition. However the time needed to delineate the…

Image and Video Processing · Electrical Eng. & Systems 2020-11-17 David Gillespie , Connah Kendrick , Ian Boon , Cheng Boon , Tim Rattay , Moi Hoon Yap

Early prostate cancer detection and staging from MRI are extremely challenging tasks for both radiologists and deep learning algorithms, but the potential to learn from large and diverse datasets remains a promising avenue to increase their…

Computer Vision and Pattern Recognition · Computer Science 2022-06-14 Abhejit Rajagopal , Ekaterina Redekop , Anil Kemisetti , Rushi Kulkarni , Steven Raman , Kirti Magudia , Corey W. Arnold , Peder E. Z. Larson

We hypothesize that anatomical priors can be viable mediums to infuse domain-specific clinical knowledge into state-of-the-art convolutional neural networks (CNN) based on the U-Net architecture. We introduce a probabilistic population…

Image and Video Processing · Electrical Eng. & Systems 2021-09-22 Anindo Saha , Matin Hosseinzadeh , Henkjan Huisman

Identifying disease-indicative genes is critical for deciphering disease mechanisms and has attracted significant interest in biomedical research. Spatial transcriptomics offers unprecedented insights for the detection of disease-specific…

Methodology · Statistics 2024-09-05 Qicheng Zhao , Qihuang Zhang

Surgery for brain cancer is a major problem in neurosurgery. The diffuse infiltration into the surrounding normal brain by these tumors makes their accurate identification by the naked eye difficult. Since surgery is the common treatment…

A significant challenge in solid tumors is reliably distinguishing confounding pathologies from malignant neoplasms on routine imaging. While radiomics methods seek surrogate markers of lesion heterogeneity on CT/MRI, many aggregate…

Early detection of cancerous tissue is crucial for long-term patient survival. In the head and neck region, a typical diagnostic procedure is an endoscopic intervention where a medical expert manually assesses tissue using RGB camera…

Image and Video Processing · Electrical Eng. & Systems 2020-07-03 Marcel Bengs , Nils Gessert , Wiebke Laffers , Dennis Eggert , Stephan Westermann , Nina A. Mueller , Andreas O. H. Gerstner , Christian Betz , Alexander Schlaefer

In spite of the diverse literature on nonstationary spatial modeling and approximate Gaussian process (GP) methods, there are no general approaches for conducting fully Bayesian inference for moderately sized nonstationary spatial data sets…

Computation · Statistics 2020-07-01 Mark D. Risser , Daniel Turek

Recent advancements in remote sensing technology and the increasing size of satellite constellations allows massive geophysical information to be gathered daily on a global scale by numerous platforms of different fidelity. The…

Computation · Statistics 2021-05-11 Si Cheng , Bledar A. Konomi , Jessica L. Matthews , Georgios Karagiannis , Emily L. Kang

Medical image segmentation is a challenging task, particularly due to inter- and intra-observer variability, even between medical experts. In this paper, we propose a novel model, called Probabilistic Inter-Observer and iNtra-Observer…

Image and Video Processing · Electrical Eng. & Systems 2023-07-24 Arne Schmidt , Pablo Morales-Álvarez , Rafael Molina

Fully supervised deep models have shown promising performance for many medical segmentation tasks. Still, the deployment of these tools in clinics is limited by the very timeconsuming collection of manually expert-annotated data. Moreover,…

Image and Video Processing · Electrical Eng. & Systems 2024-11-06 Robin Trombetta , Olivier Rouvière , Carole Lartizien

Prostate cancer (PCa) is the most frequently diagnosed malignancy in men and the eighth leading cause of cancer death worldwide. Multiparametric MRI (mpMRI) has become central to the diagnostic pathway for men at intermediate risk,…

Breast cancer is one of the most common cancers in women worldwide, and early detection can significantly reduce the mortality rate of breast cancer. It is crucial to take multi-scale information of tissue structure into account in the…

Computer Vision and Pattern Recognition · Computer Science 2021-01-01 Mo Zhang , Quanzheng Li

Spatial whole-brain Bayesian modeling of task-related functional magnetic resonance imaging (fMRI) is a great computational challenge. Most of the currently proposed methods therefore do inference in subregions of the brain separately or do…

Computation · Statistics 2017-01-03 Per Sidén , Anders Eklund , David Bolin , Mattias Villani

One of the goals of computer-aided surgery is to match intraoperative data to preoperative images of the anatomy and add complementary information that can facilitate the task of surgical navigation. In this context, mechanical palpation…

Robotics · Computer Science 2015-09-22 Elif Ayvali , Rangaprasad Arun Srivatsan , Long Wang , Rajarshi Roy , Nabil Simaan , Howie Choset