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Biological evolution can be conceptualized as a search process in the space of gene sequences guided by the fitness landscape, a mapping that assigns a measure of reproductive value to each genotype. Here we discuss probabilistic models of…

Populations and Evolution · Quantitative Biology 2024-04-10 Joachim Krug , Daniel Oros

Genetic regulatory networks with adaptive responses are widely studied in biology. Usually, models consisting only of a few nodes have been considered. They present one input receptor for activation and one output node where the adaptive…

Molecular Networks · Quantitative Biology 2016-07-20 Pablo Kaluza , Masayo Inoue

Distribution networks -- from vasculature to urban transportation systems -- are prevalent in both the natural and consumer worlds. These systems are intrinsically physical in composition and are embedded into real space, properties that…

Quantitative Methods · Quantitative Biology 2016-12-26 Lia Papadopoulos , Pablo Blinder , Henrik Ronellenfitsch , Florian Klimm , Eleni Katifori , David Kleinfeld , Danielle S. Bassett

Understanding causal relationships within Gene Regulatory Networks (GRNs) is essential for unraveling the gene interactions in cellular processes. However, causal discovery in GRNs is a challenging problem for multiple reasons including the…

Artificial Intelligence · Computer Science 2023-10-06 Trang Nguyen , Alexander Tong , Kanika Madan , Yoshua Bengio , Dianbo Liu

Structural changes in a network representation of a system (e.g.,different experimental conditions, time evolution), can provide insight on its organization, function and on how it responds to external perturbations. The deeper…

Data Analysis, Statistics and Probability · Physics 2021-01-04 Leonardo L. Portes , Michael Small

Motivated by a recently introduced network growth mechanism that rely on the ranking of node prestige measures [S. Fortunato \emph{et al}., Phys. Rev. Lett. \textbf{96}, 218701 (2006)], a rank-based model for weighted network evolution is…

Disordered Systems and Neural Networks · Physics 2015-06-25 Liang Tian , Da-Ning Shi , Chen-Ping Zhu

Biological neural networks are characterized by their high degree of plasticity, a core property that enables the remarkable adaptability of natural organisms. Importantly, this ability affects both the synaptic strength and the topology of…

Neural and Evolutionary Computing · Computer Science 2024-06-17 Erwan Plantec , Joachin W. Pedersen , Milton L. Montero , Eleni Nisioti , Sebastian Risi

Modelling gene regulatory networks not only requires a thorough understanding of the biological system depicted but also the ability to accurately represent this system from a mathematical perspective. Throughout this chapter, we aim to…

Quantitative Methods · Quantitative Biology 2018-05-04 Olivia Angelin-Bonnet , Patrick J. Biggs , Matthieu Vignes

We investigate a model of evolving random network, introduced by us previously {[}{\it Phys. Rev. Lett.} {\bf 83}, 5587 (1999){]} . The model is a generalization of the Bak-Sneppen model of biological evolution, with the modification that…

Statistical Mechanics · Physics 2009-10-31 Frantisek Slanina , Miroslav Kotrla

Networks are widely used to represent interaction pattern among the components in complex systems. Structures of real networks from differ- ent domains may vary quite significantly. Since there is an interplay be- tween network architecture…

Quantitative Methods · Quantitative Biology 2016-05-10 Krishanu Deyasi , Shashankaditya Upadhyay , Anirban Banerjee

Models of growing networks are a central topic in network science. In these models, vertices are usually labeled by their arrival time, distinguishing even those node pairs whose structural roles are identical. In contrast, unlabeled…

Physics and Society · Physics 2025-09-23 Harrison Hartle , Brennan Klein , Dmitri Krioukov , P. L. Krapivsky

In biological evolution complex neural structures grow from a handful of cellular ingredients. As genomes in nature are bounded in size, this complexity is achieved by a growth process where cells communicate locally to decide whether to…

Neural and Evolutionary Computing · Computer Science 2024-05-15 Eleni Nisioti , Erwan Plantec , Milton Montero , Joachim Winther Pedersen , Sebastian Risi

Gene duplication is a fundamental evolutionary mechanism that contributes to biological complexity and diversity (Fortna et al., 2004). Traditionally, research has focused on the duplication of gene sequences (Zhang, 1914). However,…

Molecular Networks · Quantitative Biology 2024-05-07 Ashley Scruse , Jonathan Arnold , Robert Robinson

With the evolution of social networks, the network structure shows dynamic nature in which nodes and edges appear as well as disappear for various reasons. The role of a node in the network is presented as the number of interactions it has…

Social and Information Networks · Computer Science 2018-03-02 Shailesh Kumar Jaiswal , Nabajyoti Medhi , Manjish Pal , Mridul Sahu , Prashant Sahu , Amal Dev Sarma

A central and long-standing issue in evolutionary theory is the origin of the biological variation upon which natural selection acts1. Some hypotheses suggest that evolutionary change represents an adaptation to the surrounding environment…

Statistical Mechanics · Physics 2007-05-23 J. Podani , Z. N. Oltvai , H. Jeong , B. Tombor , A. -L. Barabasi , E. Szathmary

Evolving Neural Networks (NNs) has recently seen an increasing interest as an alternative path that might be more successful. It has many advantages compared to other approaches, such as learning the architecture of the NNs. However, the…

Neural and Evolutionary Computing · Computer Science 2022-03-15 Abdullah Khalili , Abdelhamid Bouchachia

We build networks of genetic similarity in which the nodes are organisms sampled from biological populations. The procedure is illustrated by constructing networks from genetic data of a marine clonal plant. An important feature in the…

Populations and Evolution · Quantitative Biology 2008-01-23 E. Hernandez-Garcia , A. F. Rozenfeld , V. M. Eguiluz , S. Arnaud-Haond , C. M. Duarte

Development combines three basic processes asymmetric --- cell division, signaling and gene regulation --- in a multitude of ways to create an overwhelming diversity of multicellular life-forms. Here, we attempt to chart this diversity…

Molecular Networks · Quantitative Biology 2020-01-01 Somya Mani , Tsvi Tlusty

In many complex systems, the dynamic processes that take place on a network and the changes in the network topology are intertwined. Here, we propose a model of coevolutionary dynamics of information spreading which is accompanied with link…

Physics and Society · Physics 2023-11-01 Jeehye Choi , Byungjoon Min

Epidemics on complex networks is a widely investigated topic in the last few years, mainly due to the last pandemic events. Usually, real contact networks are dynamic, hence much effort has been invested in studying epidemics on evolving…

Physics and Society · Physics 2022-05-18 Hillel Sanhedrai , Shlomo Havlin