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Open-source software is a complex system; its development depends on the self-coordinated action of a large number of agents. This study follows the size of the building blocks, called "packages", of the Ubuntu Linux operating system over…

Physics and Society · Physics 2013-03-04 Marco Gherardi , Salvatore Mandrà , Bruno Bassetti , Marco Cosentino Lagomarsino

The capacity of cells and organisms to respond to challenging conditions in a repeatable manner is limited by a finite repertoire of pre-evolved adaptive responses. Beyond this capacity, cells can use exploratory dynamics to cope with a…

Molecular Networks · Quantitative Biology 2017-07-05 Hallel I. Schreier , Yoav Soen , Naama Brenner

Random scale-free overlay topologies provide a number of properties like for example high resilience against failures of random nodes, small (average) diameter as well as good expansion and congestion characteristics that make them…

Networking and Internet Architecture · Computer Science 2013-07-16 Ingo Scholtes

Evolutionary dynamics is often viewed as a subtle process of change accumulation that causes a divergence among organisms and their genomes. However, this interpretation is an inheritance of a gradualistic view that has been challenged at…

Populations and Evolution · Quantitative Biology 2018-07-27 Jacobo Aguirre , Pablo Catalán , José A. Cuesta , Susanna Manrubia

Metabolic networks are known to be scale free but the evolutionary origin of this structural property is not clearly understood. One way of studying the dynamical process is to compare the metabolic networks of species that have arisen at…

Molecular Networks · Quantitative Biology 2007-05-23 Shalini , Areejit Samal , Varun Giri , Sandeep Krishna , N. Raghuram , Sanjay Jain

The dynamics of gene regulatory networks is governed by the interaction between deterministic biochemical reactions and molecular noise. To understand how gene regulatory networks process information during cell state transitions, we study…

Molecular Networks · Quantitative Biology 2025-09-11 Miguel Ángel García-Ariza , Alessandro Bravetti , Pablo Padilla , J Roberto Romero-Arias

From the proliferative mechanisms generating neurons from progenitor cells to neuron migration and synaptic connection formation, several vicissitudes culminate in the mature brain. Both component loss and gain remain ubiquitous during…

Neurons and Cognition · Quantitative Biology 2024-08-06 Rodrigo Siqueira Kazu , Kleber Neves , Bruno Mota

One of the grand challenges of cell biology is inferring the gene regulatory network (GRN) which describes interactions between genes and their products that control gene expression and cellular function. We can treat this as a causal…

Machine Learning · Computer Science 2023-12-27 Lazar Atanackovic , Alexander Tong , Bo Wang , Leo J. Lee , Yoshua Bengio , Jason Hartford

Neural networks and evolutionary computation have a rich intertwined history. They most commonly appear together when an evolutionary algorithm optimises the parameters and topology of a neural network for reinforcement learning problems,…

Neural and Evolutionary Computing · Computer Science 2016-04-15 Alexander W. Churchill , Siddharth Sigtia , Chrisantha Fernando

Extensive studies have been done to understand the principles behind architectures of real networks. Recently, evidences for hierarchical organization in many real networks have also been reported. Here, we present a new hierarchical model…

Other Condensed Matter · Physics 2007-05-23 J. C. Nacher , N. Ueda , M. Kanehisa , T. Akutsu

Scale independence is a ubiquitous feature of complex systems which implies a highly skewed distribution of resources with no characteristic scale. Research has long focused on why systems as varied as protein networks, evolution and stock…

Physics and Society · Physics 2016-02-08 Laurent Hébert-Dufresne , Antoine Allard , Jean-Gabriel Young , Louis J. Dubé

Self-adaptation solutions need to periodically monitor, reason about, and adapt a running system. The adaptation step involves generating an adaptation strategy and applying it to the running system whenever an anomaly arises. In this…

Software Engineering · Computer Science 2023-08-16 Jia Li , Shiva Nejati , Mehrdad Sabetzadeh

A common feature of biological networks is the geometric property of self-similarity. Molecular regulatory networks through to circulatory systems, nervous systems, social systems and ecological trophic networks, show self-similar…

Molecular Networks · Quantitative Biology 2012-03-09 Simon DeDeo , David C. Krakauer

Rapid advance of experimental techniques provides an unprecedented in-depth view into complex developmental processes. Still, little is known on how the complexity of multicellular organisms evolved by elaborating developmental programs and…

Molecular Networks · Quantitative Biology 2021-07-16 Somya Mani , Tsvi Tlusty

Gene regulatory networks (GRNs) define the regulatory relationships among molecules such as transcription factors, chromatin remodelers, and target genes. GRNs play a critical role in diverse biological processes, including development,…

Molecular Networks · Quantitative Biology 2026-02-24 Junha Shin , Spencer Halberg-Spencer , Yuda Liu , Suvojit Hazra , Erika Da-Inn Lee , Sushmita Roy

Robust and efficient design of networks on a realistic geographical space is one of the important issues for the realization of dependable communication systems. In this paper, based on a percolation theory and a geometric graph property,…

Data Analysis, Statistics and Probability · Physics 2011-11-04 Yukio Hayashi

By default, the Linux network stack is not configured for highspeed large file transfer. The reason behind this is to save memory resources. It is possible to tune the Linux network stack by increasing the network buffers size for…

Neural and Evolutionary Computing · Computer Science 2018-09-03 Bartosz Gembala , Anis Yazidi , Hårek Haugerud , Stefano Nichele

Many methods have been developed for finding the commonalities between different organisms to study their phylogeny. The structure of metabolic networks also reveal valuable insights into metabolic capacity of species as well as into the…

Molecular Networks · Quantitative Biology 2016-04-08 Krishanu Deyasi , Anirban Banerjee , Bony Deb

Despite their claimed biological plausibility, most self organizing networks have strict topological constraints and consequently they cannot take into account a wide range of external stimuli. Furthermore their evolution is conditioned by…

General Physics · Physics 2010-04-26 Ignazio Licata , Luigi Lella

We show that not only preferential attachment but also preferential depletion leads to scale-free networks. The resulting degree distribution exponents is typically less than two (5/3) as opposed to the case of the growth models studied…

Physics and Society · Physics 2015-05-27 Christian M. Schneider , Lucilla de Arcangelis , Hans J. Herrmann
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