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We investigate the evolution of Boolean networks subject to a selective pressure which favors robustness against noise, as a model of evolved genetic regulatory systems. By mapping the evolutionary process into a statistical ensemble and…

Disordered Systems and Neural Networks · Physics 2012-04-11 Tiago P. Peixoto

Genetic regulatory networks (GRNs) have been widely studied, yet there is a lack of understanding with regards to the final size and properties of these networks, mainly due to no network currently being complete. In this study, we analyzed…

Molecular Networks · Quantitative Biology 2019-03-13 Adrian I. Campos-González , Julio A. Freyre-González

Software evolution is a fundamental process that transcends the realm of technical artifacts and permeates the entire organizational structure of a software project. By means of a longitudinal empirical study of 18 large open-source…

Software Engineering · Computer Science 2016-10-20 Mitchell Joblin , Sven Apel , Wolfgang Mauerer

This paper introduces a method to generate hierarchically modular networks with prescribed node degree list and proposes a metric to measure network modularity based on the notion of edge distance. The generated networks are used as test…

Neural and Evolutionary Computing · Computer Science 2009-03-17 Susan Khor

Co-evolution exhibited by a network system, involving the intricate interplay between the dynamics of the network itself and the subsystems connected by it, is a key concept for understanding the self-organized, flexible nature of…

Physics and Society · Physics 2012-11-14 Takaaki Aoki , Toshio Aoyagi

The co-evolution of network topology and dynamics is studied in an evolutionary Boolean network model that is a simple model of gene regulatory network. We find that a critical state emerges spontaneously resulting from interplay between…

Statistical Mechanics · Physics 2007-05-23 Min Liu , Kevin E. Bassler

Regulatory networks consist of interacting molecules with a high degree of mutual chemical specificity. How can these molecules evolve when their function depends on maintenance of interactions with cognate partners and simultaneous…

Populations and Evolution · Quantitative Biology 2017-11-01 Tamar Friedlander , Roshan Prizak , Nicholas H. Barton , Gašper Tkačik

Software systems are composed of many interacting elements. A natural way to abstract over software systems is to model them as graphs. In this paper we consider software dependency graphs of object-oriented software and we study one…

Software Engineering · Computer Science 2017-04-11 Vincenzo Musco , Martin Monperrus , Philippe Preux

We propose a growing network model that consists of two tunable mechanisms: growth by merging modules which are represented as complete graphs and a fitness-driven preferential attachment. Our model exhibits the three prominent statistical…

Molecular Networks · Quantitative Biology 2007-07-31 Kazuhiro Takemoto , Chikoo Oosawa

Systems as diverse as genetic networks or the world wide web are best described as networks with complex topology. A common property of many large networks is that the vertex connectivities follow a scale-free power-law distribution. This…

Disordered Systems and Neural Networks · Physics 2015-06-25 Albert-Laszlo Barabasi , Reka Albert

Genetic regulatory networks enable cells to respond to the changes in internal and external conditions by dynamically coordinating their gene expression profiles. Our ability to make quantitative measurements in these biochemical circuits…

Biological Physics · Physics 2015-03-17 Aleksandra M Walczak , Gašper Tkačik

Generative mechanisms which lead to empirically observed structure of networked systems from diverse fields like biology, technology and social sciences form a very important part of study of complex networks. The structure of many…

Physics and Society · Physics 2015-12-03 Snehal M. Shekatkar , G. Ambika

A cell's behavior is a consequence of the complex interactions between its numerous constituents, such as DNA, RNA, proteins and small molecules. Cells use signaling pathways and regulatory mechanisms to coordinate multiple processes,…

Molecular Networks · Quantitative Biology 2007-09-12 Reka Albert

We model the evolution of the Internet at the Autonomous System level as a process of competition for users and adaptation of bandwidth capability. We find the exponent of the degree distribution as a simple function of the growth rates of…

Disordered Systems and Neural Networks · Physics 2009-11-10 M. Angeles Serrano , Marian Boguna , Albert Diaz-Guilera

We study a genetic regulatory network model developed to demonstrate that genetic robustness can evolve through stabilizing selection for optimal phenotypes. We report preliminary results on whether such selection could result in a…

Molecular Networks · Quantitative Biology 2010-12-07 Volkan Sevim , Per Arne Rikvold

The time taken for gene expression varies not least because proteins vary in length considerably. This paper uses an abstract, tuneable Boolean regulatory network model to explore gene expression time variation. In particular, it is shown…

Biomolecules · Quantitative Biology 2016-03-16 Larry Bull

Bacterial genomes and large-scale computer software projects both consist of a large number of components (genes or software packages) connected via a network of mutual dependencies. Components can be easily added or removed from individual…

Molecular Networks · Quantitative Biology 2013-08-12 Tin Yau Pang , Sergei Maslov

In this letter, we proposed an ungrowing scale-free network model, wherein the total number of nodes is fixed and the evolution of network structure is driven by a rewiring process only. In spite of the idiographic form of $G$, by using a…

Statistical Mechanics · Physics 2015-06-25 Yan-Bo Xie , Tao Zhou , Bing-Hong Wang

We investigate the evolution rules and degree distribution properties of the Software Heritage dataset, a large-scale growing network linking software source-code versions from open-source communities. The network spans more than 40 years…

Data Analysis, Statistics and Probability · Physics 2026-01-29 Guillaume Rousseau

Network science provides an indispensable theoretical framework for studying the structure and function of real complex systems. Different network models are often used for finding the rules that govern their evolution, whereby the correct…

Physics and Society · Physics 2020-09-02 Ana Vranić , Marija Mitrović Dankulov