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Related papers: BiOnt: Deep Learning using Multiple Biomedical Ont…

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Computational drug discovery provides an efficient tool helping large scale lead molecules screening. One of the major tasks of lead discovery is identifying molecules with promising binding affinities towards a target, a protein in…

Biological Physics · Physics 2019-09-18 Liangzhen Zheng , Jingrong Fan , Yuguang Mu

Generative pre-trained transformer (GPT) models have shown promise in clinical entity and relation extraction tasks because of their precise extraction and contextual understanding capability. In this work, we further leverage the Unified…

Computation and Language · Computer Science 2024-07-16 Kriti Bhattarai , Inez Y. Oh , Zachary B. Abrams , Albert M. Lai

Objective: Human-curated disease ontologies are widely used for diagnostic evaluation, treatment and data comparisons over time, and clinical decision support. The classification principles underlying these ontologies are guided by the…

Molecular Networks · Quantitative Biology 2021-04-02 Giorgio Grani , Lorenzo Madeddu , Paola Velardi

Diseases involve complex processes and modifications to the cellular machinery. The gene expression profile of the affected cells contains characteristic patterns linked to a disease. Hence, biological knowledge pertaining to a disease can…

Quantitative Methods · Quantitative Biology 2020-04-13 Thomas Gaudelet , Noel Malod-Dognin , Jon Sanchez-Valle , Vera Pancaldi , Alfonso Valencia , Natasa Przulj

The best evidence concerning comparative treatment effectiveness comes from clinical trials, the results of which are reported in unstructured articles. Medical experts must manually extract information from articles to inform…

Computation and Language · Computer Science 2022-01-11 Benjamin E. Nye , Jay DeYoung , Eric Lehman , Ani Nenkova , Iain J. Marshall , Byron C. Wallace

The rapid advancement of large language models (LLMs) has opened new boundaries in the extraction and synthesis of medical knowledge, particularly within evidence synthesis. This paper reviews the state-of-the-art applications of LLMs in…

We present a joint model for entity-level relation extraction from documents. In contrast to other approaches - which focus on local intra-sentence mention pairs and thus require annotations on mention level - our model operates on entity…

Computation and Language · Computer Science 2021-12-06 Markus Eberts , Adrian Ulges

Tagging based relational triple extraction methods are attracting growing research attention recently. However, most of these methods take a unidirectional extraction framework that first extracts all subjects and then extracts objects and…

Computation and Language · Computer Science 2022-01-06 Feiliang Ren , Longhui Zhang , Xiaofeng Zhao , Shujuan Yin , Shilei Liu , Bochao Li

Translating biomedical ontologies is an important challenge, but doing it manually requires much time and money. We study the possibility to use open-source knowledge bases to translate biomedical ontologies. We focus on two aspects:…

Quantitative Methods · Quantitative Biology 2020-04-08 Léo Bouscarrat , Antoine Bonnefoy , Cécile Capponi , Carlos Ramisch

Ontologies have become essential in today's digital age as a way of organising the vast amount of readily available unstructured text. In providing formal structure to this information, ontologies have immense value and application across…

Computation and Language · Computer Science 2025-11-11 Dekai Zhang , Simone Conia , Antonio Rago

Machine learning has been successfully used in critical domains, such as medicine. However, extracting meaningful insights from biomedical data is often constrained by the lack of their available disease labels. In this research, we…

Quantitative Methods · Quantitative Biology 2025-04-02 Hido Pinto , Eran Segal

We present BioRAGent, an interactive web-based retrieval-augmented generation (RAG) system for biomedical question answering. The system uses large language models (LLMs) for query expansion, snippet extraction, and answer generation while…

Computation and Language · Computer Science 2024-12-18 Samy Ateia , Udo Kruschwitz

Retrieval-augmented learning based on radiology reports has emerged as a promising direction to improve performance on long-tail medical imaging tasks, such as rare disease detection in chest X-rays. Most existing methods rely on comparing…

Machine Learning · Computer Science 2025-08-28 Felix Nützel , Mischa Dombrowski , Bernhard Kainz

Previous works on key information extraction from visually rich documents (VRDs) mainly focus on labeling the text within each bounding box (i.e., semantic entity), while the relations in-between are largely unexplored. In this paper, we…

Computation and Language · Computer Science 2021-10-20 Yue Zhang , Bo Zhang , Rui Wang , Junjie Cao , Chen Li , Zuyi Bao

Relation Extraction (RE) is one of the fundamental tasks in Information Extraction and Natural Language Processing. Dependency trees have been shown to be a very useful source of information for this task. The current deep learning models…

Computation and Language · Computer Science 2019-07-09 Amir Pouran Ben Veyseh , Thien Huu Nguyen , Dejing Dou

Relation extraction is a type of information extraction task that recognizes semantic relationships between entities in a sentence. Many previous studies have focused on extracting only one semantic relation between two entities in a single…

Computation and Language · Computer Science 2021-03-08 Seongsik Park , Harksoo Kim

We present a novel end-to-end neural model to extract entities and relations between them. Our recurrent neural network based model captures both word sequence and dependency tree substructure information by stacking bidirectional…

Computation and Language · Computer Science 2016-06-09 Makoto Miwa , Mohit Bansal

Relation extraction is a crucial task in natural language processing, with broad applications in knowledge graph construction and literary analysis. However, the complex context and implicit expressions in novel texts pose significant…

Computation and Language · Computer Science 2025-07-08 Yuchen Yan , Hanjie Zhao , Senbin Zhu , Hongde Liu , Zhihong Zhang , Yuxiang Jia

Large language models (LLMs) have demonstrated dominating performance in many NLP tasks, especially on generative tasks. However, they often fall short in some information extraction tasks, particularly those requiring domain-specific…

Computation and Language · Computer Science 2023-09-22 Junyi Bian , Jiaxuan Zheng , Yuyi Zhang , Shanfeng Zhu

Background and Objective: Biomedical Named Entity Recognition (BioNER) is a foundational task in medical informatics, crucial for downstream applications like drug discovery and clinical trial matching. However, adapting general-domain…

Computation and Language · Computer Science 2025-12-30 Jian Chen , Leilei Su , Cong Sun
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