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Related papers: Variations in Proteins Dielectric Constants

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We present an approximate method for calculating the electrostatic free energy of concentrated protein solutions. Our method uses a cell model and accounts for both the coulomb energy and the entropic cost of Donnan salt partitioning. The…

Biological Physics · Physics 2013-04-10 Shradha Mishra , Jeremy D. Schmit

The evolution of static dielectric constants and polarization with doping are analyzed and discussed using established experimental results. The variation of screened Coulomb potential with doping is derived theoretically to justify the…

Strongly Correlated Electrons · Physics 2009-11-10 Andrew Das Arulsamy

Electrophoretic separations of proteins are widely used in proteomic analyses, and rely heavily on SDS electrophoresis. This mode of separation is almost exclusively used when a single dimension separation is performed, and generally…

Genomics · Quantitative Biology 2010-05-07 Thierry Rabilloud

We consider the dependence of the electron transfer in photosynthetic complexes on correlation properties of random fluctuations of the protein environment. The electron subsystem is modeled by a finite network of connected electron…

Biological Physics · Physics 2015-06-23 Alexander I. Nesterov , Gennady P. Berman

We study the dynamics of hydration water/protein association in folded proteins, using lysozyme and myoglobin as examples. Extensive molecular dynamics simulations are performed to identify underlying mechanisms of the dynamical transition…

Soft Condensed Matter · Physics 2015-05-13 J. Servantie , C. Atilgan , A. R. Atilgan

The diffraction pattern of a single non-periodic compact object, such as a molecule, is continuous and is proportional to the square modulus of the Fourier transform of that object. When arrayed in a crystal, the coherent sum of the…

In biological and synthetic materials, many important processes involve charges that are present in a medium with spatially varying dielectric permittivity. To accurately understand the role of electrostatic interactions in such systems, it…

Soft Condensed Matter · Physics 2013-09-30 Vikram Jadhao , Francisco J. Solis , Monica Olvera de la Cruz

We discuss recent investigations of the interaction of polyelectrolytes with proteins. In particular, we review our recent studies on the interaction of simple proteins such as human serum albumin (HSA) or lysozyme with linear…

Soft Condensed Matter · Physics 2018-10-09 Xiao Xu , Stefano Angioletti-Uberti , Yan Lu , Joachim Dzubiella , Matthias Ballauff

Electrically driven adiabatic changes of temperature are identified in the archetypal electrocaloric material PbSc0.5Ta0.5O3 by comparing isothermal changes of electrical polarization due to slow variation of electric field, and adiabatic…

Materials Science · Physics 2021-01-22 S. Crossley , R. W. Whatmore , N. D. Mathur , X. Moya

A robust, simple and fast procedure for the calculation of uncertainties in relative static dielectric permittivity ($\varepsilon_s$) computed via molecular dynamics (MD) is proposed. It arises as a direct application of well founded…

Chemical Physics · Physics 2019-07-22 Hernán R. Sánchez , Ramiro M. Irastorza , C. Manuel Carlevaro

Dipolar susceptibility of interfacial water and the corresponding interface dielectric constant were calculated from numerical molecular dynamics simulations for neutral and charged states of buckminsterfullerene C$_{60}$. Dielectric…

Proteins change their charge state through protonation and redox reactions as well as through binding charged ligands. The free energy of these reactions are dominated by solvation and electrostatic energies and modulated by protein…

Biomolecules · Quantitative Biology 2016-02-26 Marilyn R. Gunner , Nathan A. Baker

We introduce a novel approach to sample the canonical ensemble at constant temperature and applied electric potential. Our approach can be straightforwardly implemented into any density-functional theory code. Using thermopotentiostat…

Materials Science · Physics 2021-04-07 F. Deißenbeck , C. Freysoldt , M. Todorova , J. Neugebauer , S. Wippermann

Protein crystal production is a major bottleneck for the structural characterisation of proteins. To advance beyond large-scale screening, rational strategies for protein crystallization are crucial. Understanding how chemical anisotropy…

Biomolecules · Quantitative Biology 2022-05-03 Amir R. Khan , Susan James , Michelle K. Quinn , Irem Altan , Patrick Charbonneau , Jennifer J. McManus

The contribution of electrostatic interactions to the free energy of binding between model protein and a ceramic implant surface in the aqueous solvent, considered in the framework of the non-local electrostatic model, is calculated as a…

Biological Physics · Physics 2014-07-29 A. I. Rubinstein , R. F. Sabirianov , F. Namavar

Complex electrical permittivity measurements in (1-x)[Pb(Mg1/3 Nb2/3)O3]-xPbTiO3 ceramics for 0.10 x 0.40 were performed in the frequency and temperature range from 1 kHz to 100 kHz and from 15 to 600 K, respectively. Unexpected dielectric…

Materials Science · Physics 2009-11-10 M. H. Lente , A. L. Zanin , E. R. M. Andreeta , I. A. Santos , D. Garcia , J. A. Eiras

Materials with high dielectric constant are in great demand for the miniaturization of electronic devices. More specifically, high dielectric constant polymer-ceramic composites are useful for embedded capacitor applications. A composite…

Materials Science · Physics 2013-01-18 P. Thomas , R. S. Ernest Ravindran , K. B. R. Varma

We have studied the real part of the dielectric constant of water from 100 Hz to 1 MHz. We have found that there is a frequency where the dielectric constant is independent of temperature, and called this the isopermitive point. Below this…

Chemical Physics · Physics 2015-05-20 A. Angulo-Sherman , H. Mercado-Uribe

The rigidity and flexibility of homologous psychrophilic(P), mesophilic(M) and thermophilic(T) proteins have been investigated at the global and local levels in terms of packing factor and atomic fluctuations obtained from B-factors. For…

Biological Physics · Physics 2021-06-08 Srikanta Sen , Munna Sarkar

The electric field dielectric polarization-based separations mechanism represents a novel method for separating solutions at small length scales. An electric field gradient with a maximum strength of $\mathrm{0.4~MV/m}$ applied across a…

Chemical Physics · Physics 2023-11-29 Gaurav Anand , Samira Safaripour , Craig Snoeyink