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Related papers: The Parallelism Motifs of Genomic Data Analysis

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Computer simulations of complex population genetic models are an essential tool for making sense of the large-scale datasets of multiple genome sequences from a single species that are becoming increasingly available. A widely used approach…

Populations and Evolution · Quantitative Biology 2026-04-23 Parul Johri , Fanny Pouyet , Brian Charlesworth

Gaussian processes (GP) are Bayesian non-parametric models that are widely used for probabilistic regression. Unfortunately, it cannot scale well with large data nor perform real-time predictions due to its cubic time cost in the data size.…

Machine Learning · Computer Science 2014-08-12 Jie Chen , Nannan Cao , Kian Hsiang Low , Ruofei Ouyang , Colin Keng-Yan Tan , Patrick Jaillet

Gaussian processes (GP) are Bayesian non-parametric models that are widely used for probabilistic regression. Unfortunately, it cannot scale well with large data nor perform real-time predictions due to its cubic time cost in the data size.…

Machine Learning · Statistics 2013-05-27 Jie Chen , Nannan Cao , Kian Hsiang Low , Ruofei Ouyang , Colin Keng-Yan Tan , Patrick Jaillet

Significant volumes of knowledge have been accumulated in recent years linking subtle genetic variations to a wide variety of medical disorders from Cystic Fibrosis to mental retardation. Nevertheless, there are still great challenges in…

Genomics · Quantitative Biology 2016-11-17 Yaniv Erlich , Assaf Gordon , Michael Brand , Gregory J. Hannon , Partha P. Mitra

High throughput sequencing is a technology that allows for the generation of millions of reads of genomic data regarding a study of interest, and data from high throughput sequencing platforms are usually count compositions. Subsequent…

Quantitative Methods · Quantitative Biology 2017-04-07 Jia R. Wu , Jean M. Macklaim , Briana L. Genge , Gregory B. Gloor

In this era of large-scale data, distributed systems built on top of clusters of commodity hardware provide cheap and reliable storage and scalable processing of massive data. Here, we review recent work on developing and implementing…

Distributed, Parallel, and Cluster Computing · Computer Science 2015-07-28 Jiyan Yang , Xiangrui Meng , Michael W. Mahoney

The advent of high-throughput sequencing technologies has revolutionized genome analysis by enabling the rapid and cost-effective sequencing of large genomes. Despite these advancements, the increasing complexity and volume of genomic data…

Genomics · Quantitative Biology 2025-03-06 Can Firtina

Genome sequence analysis, which examines the DNA sequences of organisms, drives advances in many critical medical and biotechnological fields. Given its importance and the exponentially growing volumes of genomic sequence data, there are…

Recent advances in reasoning models have demonstrated significant improvements in accuracy by employing detailed and comprehensive reasoning processes. However, generating these lengthy reasoning sequences is computationally expensive and…

Computation and Language · Computer Science 2025-08-27 Yijiong Yu

Data originating from the Web, sensor readings and social media result in increasingly huge datasets. The so called Big Data comes with new scientific and technological challenges while creating new opportunities, hence the increasing…

Artificial Intelligence · Computer Science 2020-02-19 Ilias Tachmazidis , Grigoris Antoniou , Wolfgang Faber

The present and future of evolutionary algorithms depends on the proper use of modern parallel and distributed computing infrastructures. Although still sequential approaches dominate the landscape, available multi-core, many-core and…

Neural and Evolutionary Computing · Computer Science 2021-03-02 Francisco Fernández de Vega , Gustavo Olague , Francisco Chávez , Daniel Lanza , Wolfgang Banzhaf , Erik Goodman

We study the problem of computing a conjunctive query q in parallel, using p of servers, on a large database. We consider algorithms with one round of communication, and study the complexity of the communication. We are especially…

Databases · Computer Science 2014-01-10 Paul Beame , Paraschos Koutris , Dan Suciu

The immense increase in the generation of genomic scale data poses an unmet analytical challenge, due to a lack of established methodology with the required flexibility and power. We propose a first principled approach to statistical…

Heterogeneous many-cores are now an integral part of modern computing systems ranging from embedding systems to supercomputers. While heterogeneous many-core design offers the potential for energy-efficient high-performance, such potential…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-05-11 Jianbin Fang , Chun Huang , Tao Tang , Zheng Wang

There are two intertwined factors that affect performance of concurrent data structures: the ability of processes to access the data in parallel and the cost of synchronization. It has been observed that for a large class of…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-05-10 Vitaly Aksenov , Petr Kuznetsov

In order to fully utilize "big data", it is often required to use "big models". Such models tend to grow with the complexity and size of the training data, and do not make strong parametric assumptions upfront on the nature of the…

Machine Learning · Statistics 2015-04-17 Vikas Sindhwani , Haim Avron

The combination of multiple classifiers using ensemble methods is increasingly important for making progress in a variety of difficult prediction problems. We present a comparative analysis of several ensemble methods through two case…

Machine Learning · Computer Science 2013-09-20 Sean Whalen , Gaurav Pandey

In the rapidly evolving domain of next generation sequencing and bioinformatics analysis, data generation is one aspect that is increasing at a concomitant rate. The burden associated with processing large amounts of sequencing data has…

Genomics · Quantitative Biology 2015-03-11 Matthew J. Wade , Thomas P. Curtis , Russell J. Davenport

AI accelerator processing capabilities and memory constraints largely dictate the scale in which machine learning workloads (e.g., training and inference) can be executed within a desirable time frame. Training a state of the art,…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-10-12 Michael Benington , Leo Phan , Chris Pierre Paul , Evan Shoemaker , Priyanka Ranade , Torstein Collett , Grant Hodgson Perez , Christopher Krieger

The ability to learn new tasks and generalize performance to others is one of the most remarkable characteristics of the human brain and of recent AI systems. The ability to perform multiple tasks simultaneously is also a signature…

Neurons and Cognition · Quantitative Biology 2020-11-11 Giovanni Petri , Sebastian Musslick , Biswadip Dey , Kayhan Ozcimder , David Turner , Nesreen K. Ahmed , Theodore Willke , Jonathan D. Cohen
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