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Purpose: To develop a deep network architecture that would achieve fully automated radiologist-level segmentation of cancers at breast MRI. Materials and Methods: In this retrospective study, 38229 examinations (composed of 64063 individual…

Data limitation is a significant challenge in applying deep learning to medical images. Recently, the diffusion probabilistic model (DPM) has shown the potential to generate high-quality images by converting Gaussian random noise into…

Computer Vision and Pattern Recognition · Computer Science 2024-08-26 Sepehr Salem Ghahfarokhi , Tyrell To , Julie Jorns , Tina Yen , Bing Yu , Dong Hye Ye

An important part of breast cancer staging is the assessment of the sentinel axillary node for early signs of tumor spreading. However, this assessment by pathologists is not always easy and retrospective surveys often requalify the status…

Quantitative Methods · Quantitative Biology 2024-04-30 Eric Bonnet

Purpose: The scarcity of high-quality curated labeled medical training data remains one of the major limitations in applying artificial intelligence (AI) systems to breast cancer diagnosis. Deep models for mammogram analysis and mass (or…

Computer Vision and Pattern Recognition · Computer Science 2025-04-29 Han Chen , Anne L. Martel

Cancer is responsible for millions of deaths worldwide every year. Although significant progress has been achieved in cancer medicine, many issues remain to be addressed for improving cancer therapy. Appropriate cancer patient…

Machine Learning · Computer Science 2021-03-31 David Oniani , Chen Wang , Yiqing Zhao , Andrew Wen , Hongfang Liu , Feichen Shen

The interactions between tumor cells and the tumor microenvironment (TME) dictate therapeutic efficacy of radiation and many systemic therapies in breast cancer. However, to date, there is not a widely available method to reproducibly…

This paper explores machine learning (ML) models for classifying lung cancer levels to improve diagnostic accuracy and prognosis. Through parameter tuning and rigorous evaluation, we assess various ML algorithms. Techniques like minimum…

Artificial Intelligence · Computer Science 2024-12-05 Mohsen Asghari Ilani , Saba Moftakhar Tehran , Ashkan Kavei , Hamed Alizadegan

It has been widely recognized that the success of deep learning in image segmentation relies overwhelmingly on a myriad amount of densely annotated training data, which, however, are difficult to obtain due to the tremendous labor and…

Computer Vision and Pattern Recognition · Computer Science 2020-11-26 Yutong Xie , Jianpeng Zhang , Zehui Liao , Yong Xia , Chunhua Shen

This article adresses the problem of automatic squamous cells classification for cervical cancer screening using Deep Learning methods. We study different architectures on a public dataset called Herlev dataset, which consists in…

Image and Video Processing · Electrical Eng. & Systems 2019-08-20 Antoine Pirovano , Leandro G. Almeida , Said Ladjal

Merging the two cultures of deep and statistical learning provides insights into structured high-dimensional data. Traditional statistical modeling is still a dominant strategy for structured tabular data. Deep learning can be viewed…

Methodology · Statistics 2021-10-25 Anindya Bhadra , Jyotishka Datta , Nick Polson , Vadim Sokolov , Jianeng Xu

We introduce a new computer aided detection and diagnosis system for lung cancer screening with low-dose CT scans that produces meaningful probability assessments. Our system is based entirely on 3D convolutional neural networks and…

Computer Vision and Pattern Recognition · Computer Science 2020-01-22 Onur Ozdemir , Rebecca L. Russell , Andrew A. Berlin

Lung cancer is a major issue in worldwide public health, requiring early diagnosis using stable techniques. This work begins a thorough investigation of the use of machine learning (ML) methods for precise classification of lung cancer…

Computer Vision and Pattern Recognition · Computer Science 2025-01-31 Shayli Farshchiha , Salman Asoudeh , Maryam Shavali Kuhshuri , Mehrshad Eisaeid , Mohamadreza Azadie , Saba Hesaraki

In this paper we develop a statistical theory and an implementation of deep learning models. We show that an elegant variable splitting scheme for the alternating direction method of multipliers optimises a deep learning objective. We allow…

Machine Learning · Statistics 2015-09-22 Nicholas G. Polson , Brandon T. Willard , Massoud Heidari

Breast cancer (BC) remains a significant global health challenge, with personalized treatment selection complicated by the disease's molecular and clinical heterogeneity. BC treatment decisions rely on various patient-specific clinical…

Applications · Statistics 2025-07-10 Md Nahid Hasan , Md Monzur Murshed , Md Mahadi Hasan , Faysal A. Chowdhury

Cancer is a complex disease, the understanding and treatment of which are being aided through increases in the volume of collected data and in the scale of deployed computing power. Consequently, there is a growing need for the development…

The cervix is the narrow end of the uterus that connects to the vagina in the female reproductive system. Abnormal cell growth in the squamous epithelial lining of the cervix leads to cervical cancer in females. A Pap smear is a diagnostic…

Image and Video Processing · Electrical Eng. & Systems 2024-11-21 Subhasish Das , Satish K Panda , Madhusmita Sethy , Prajna Paramita Giri , Ashwini K Nanda

Diagnostic pathology, which is the basis and gold standard of cancer diagnosis, provides essential information on the prognosis of the disease and vital evidence for clinical treatment. Tumor region detection, subtype and grade…

Image and Video Processing · Electrical Eng. & Systems 2021-10-27 Jialun Wu , Haichuan Zhang , Zeyu Gao , Xinrui Bao , Tieliang Gong , Chunbao Wang , Chen Li

Precise prognostic stratification of colorectal cancer (CRC) remains a major clinical challenge due to its high heterogeneity. The conventional TNM staging system is inadequate for personalized medicine. We aimed to develop and validate a…

Machine Learning · Computer Science 2025-11-20 Zisong Wang , Xuanyu Wang , Hang Chen , Haizhou Wang , Yuxin Chen , Yihang Xu , Yunhe Yuan , Lihuan Luo , Xitong Ling , Xiaoping Liu

Breast density estimation is one of the key tasks in recognizing individuals predisposed to breast cancer. It is often challenging because of low contrast and fluctuations in mammograms' fatty tissue background. Most of the time, the breast…

Image and Video Processing · Electrical Eng. & Systems 2022-10-11 Vikash Gupta , Mutlu Demirer , Robert W. Maxwell , Richard D. White , Barbaros Selnur Erdal

Modeling tumor growth accurately is essential for understanding cancer progression and informing treatment strategies. To estimate the parameters in the tumor growth model described by a nonlinear PDE, we adopt Physics-Informed Neural…

Analysis of PDEs · Mathematics 2025-11-21 Liu Liu , Yifei Wang , Qinyu Xu , Xiaoqian Xu