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We discuss two aspects, the in vivo and in vitro difference and the modeling of noise, of integrative modeling of network dynamics in biology, using phage lambda as an example. We believe those two aspects have not been seriously…

Soft Condensed Matter · Physics 2007-05-23 P. Ao , L. Yin

Stochasticity in gene expression can give rise to fluctuations in protein levels and lead to phenotypic variation across a population of genetically identical cells. Recent experiments indicate that bursting and feedback mechanisms play…

Molecular Networks · Quantitative Biology 2015-06-22 Niraj Kumar , Thierry Platini , Rahul V. Kulkarni

Stochastic resetting and noise-enhanced stability are two phenomena which can affect the lifetime and relaxation of nonequilibrium states. They can be considered as measures of controlling the efficiency of the completion process when a…

Statistical Mechanics · Physics 2022-06-22 Karol Capała , Bartłomiej Dybiec , Ewa Gudowska-Nowak

We have analyzed the effects of the addition of external noise to non-dynamical systems displaying intrinsic noise, and established general conditions under which stochastic resonance appears. The criterion we have found may be applied to a…

Condensed Matter · Physics 2016-08-15 J. M. G. Vilar , G. Gomila , J. M. Rubí

In this paper, we investigate a decentralized control problem with nested subsystems, which is a general model for one-directional communication amongst many subsystems. The noises in our dynamics are modelled as uncertain variables which…

Optimization and Control · Mathematics 2022-06-14 Aditya Dave , Nishanth Venkatesh , Andreas A. Malikopoulos

From the flashes of fireflies to Josephson junctions and power infrastructure, networks of coupled phase oscillators provide a powerful framework to describe synchronization phenomena in many natural and engineered systems. Most real-world…

Adaptation and Self-Organizing Systems · Physics 2022-03-02 Sherwood Martineau , Tim Saffold , Timothy T. Chang , Henrik Ronellenfitsch

We propose a general approach to the question of how biological rhythms spontaneously self-regulate, based on the concept of ``stochastic feedback''. We illustrate this approach by considering the neuroautonomic regulation of the heart…

Statistical Mechanics · Physics 2009-10-30 Plamen Ch. Ivanov , Luis A. N. Amaral , Ary Goldberger , H. Eugene Stanley

Daylight plays a major role in the wake/sleep cycle in humans. Indeed, the wake/sleep system stems from biological systems that follow a circadian rhythm determined by the light/dark alternation. The oscillations can be modeled by the…

Biological Physics · Physics 2022-01-13 F. L. Tsafack Tayong , R. Yamapi , G. Filatrella

We briefly introduce noise-based logic. After describing the main motivations we outline classical, instantaneous (squeezed and non-squeezed), continuum, spike and random-telegraph-signal based schemes with applications such as circuits…

Emerging Technologies · Computer Science 2011-02-14 Laszlo B. Kish , Sunil Khatri , Sergey Bezrukov , Ferdinand Peper , Zoltan Gingl , Tamas Horvath

We show that noise-induced oscillations in a gene circuit model display stochastic coherence, that is, a maximum in the regularity of the oscillations as a function of noise amplitude. The effect is manifest as a system-size effect in a…

Molecular Networks · Quantitative Biology 2009-08-05 Robert C. Hilborn , Jessie D. Erwin

A high efficiency hardware integration of neural networks benefits from realizing nonlinearity, network connectivity and learning fully in a physical substrate. Multiple systems have recently implemented some or all of these operations, yet…

Neural and Evolutionary Computing · Computer Science 2021-06-28 Louis Andreoli , Xavier Porte , Stéphane Chrétien , Maxime Jacquot , Laurent Larger , Daniel Brunner

The paradigm of stochastic resonance (SR)---the idea that signal detection and transmission may benefit from noise---has met with great interest in both physics and the neurosciences. We investigate here the consequences of reducing the…

Biological Physics · Physics 2009-11-06 Hans E. Plesser , Theo Geisel

Previous preliminary results on the application of knowledge networks to noise reduction in stationary harmonic and weakly chaotic signals are extended to more general cases. The formalism gives a novel algorithm from which statistical…

Data Analysis, Statistics and Probability · Physics 2007-05-23 Arturo Berrones

The ability to uncover preferences from choices is fundamental for both positive economics and welfare analysis. Overwhelming evidence shows that choice is stochastic, which has given rise to random utility models as the dominant paradigm…

General Economics · Economics 2018-11-07 Carlos Alos-Ferrer , Ernst Fehr , Nick Netzer

Neurons regulate the distribution of signaling components across an extended tree-like cellular structure using both local and global feedback control. This is hypothesized to allow homeostatic control of the electrical activity of a neuron…

Adaptation and Self-Organizing Systems · Physics 2021-04-27 Saeed Aljaberi , Adriano Bellotti , Timothy O'Leary , Fulvio Forni

We address the role of noise and the issue of efficient computation in stochastic optimal control problems. We consider a class of non-linear control problems that can be formulated as a path integral and where the noise plays the role of…

Computational Physics · Physics 2009-11-10 H. J. Kappen

In this paper, we present new results for the synchronization and consensus of networks described by Ito stochastic differential equations. From the methodological viewpoint, our results are based on the use of stochastic Lyapunov…

Dynamical Systems · Mathematics 2016-02-23 Giovanni Russo , Robert Shorten

The objectives and contributions of this paper are mathematical and numerical analyses of a stochastic control problem of bounded population dynamics under ambiguity, an important but not well-studied problem, focusing on the optimality…

Optimization and Control · Mathematics 2020-07-06 H. Yoshioka , M. Tsujimura

Pluripotent embryonic stem cells are of paramount importance for biomedical research thanks to their innate ability for self-renewal and differentiation into all major cell lines. The fateful decision to exit or remain in the pluripotent…

Molecular Networks · Quantitative Biology 2018-07-04 Yen Ting Lin , Peter G. Hufton , Esther J. Lee , Davit A. Potoyan

We examine the effect of noise on societies of agents using an agent-based model of evolutionary norm emergence. Generally, we see that noisy societies are more selfish, smaller and discontent, and are caught in rounds of perpetual…

Multiagent Systems · Computer Science 2024-11-28 Stavros Anagnou , Daniel Polani , Christoph Salge