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In the absence of unobserved confounders, matching and weighting methods are widely used to estimate causal quantities including the Average Treatment Effect on the Treated (ATT). Unfortunately, these methods do not necessarily achieve…

Methodology · Statistics 2016-05-03 Chad Hazlett

Positivity violations, which occur when some subgroups either always or never receive a treatment of interest, pose significant challenges for causal effect estimation with observational data. Recent balancing weight methods have proved to…

Methodology · Statistics 2025-12-17 Martha Barnard , Jared D. Huling , Julian Wolfson

We investigate the theoretical foundations of a recently introduced entropy-based formulation of weighted least squares for the approximation of overdetermined linear systems, motivated by robust data fitting in the presence of sparse gross…

Numerical Analysis · Mathematics 2026-03-17 Felice Iavernaro , Monica Lazzo , Lorenzo Pisani

Externally controlled single-arm trials are critical to assess treatment efficacy across therapeutic indications for which randomized controlled trials are not feasible. A closely-related research design, the unanchored indirect treatment…

Methodology · Statistics 2026-02-13 Harlan Campbell , Antonio Remiro-Azócar

Estimating the joint effect of a multivariate, continuous exposure is crucial, particularly in environmental health where interest lies in simultaneously evaluating the impact of multiple environmental pollutants on health. We develop novel…

Individualized treatment rules aim to identify if, when, which, and to whom treatment should be applied. A globally aging population, rising healthcare costs, and increased access to patient-level data have created an urgent need for…

Methodology · Statistics 2019-01-04 Ying-Qi Zhao , Eric B. Laber , Yang Ning , Sumona Saha , Bruce Sands

The balanced partial entanglement (BPE) was observed to give the reflected entropy and the entanglement wedge cross-section (EWCS) for various mixed states in different theories \cite{Wen:2021qgx,Camargo:2022mme}. It can be calculated in…

High Energy Physics - Theory · Physics 2022-09-13 Qiang Wen , Haocheng Zhong

This paper proposes a~simple, yet powerful, method for balancing distributions of covariates for causal inference based on observational studies. The method makes it possible to balance an arbitrary number of quantiles (e.g., medians,…

Methodology · Statistics 2024-03-14 Maciej Beręsewicz

Inverse probability weights are commonly used in epidemiology to estimate causal effects in observational studies. Researchers can typically focus on either the average treatment effect or the average treatment effect on the treated with…

Methodology · Statistics 2022-10-05 Eli Ben-Michael , Luke Keele

With the modern software and online platforms to collect massive amount of data, there is an increasing demand of applying causal inference methods at large scale when randomized experimentation is not viable. Weighting methods that…

Methodology · Statistics 2023-08-04 Sicheng Lin , Meng Xu , Xi Zhang , Shih-Kang Chao , Ying-Kai Huang , Xiaolin Shi

There is a dearth of robust methods to estimate the causal effects of multiple treatments when the outcome is binary. This paper uses two unique sets of simulations to propose and evaluate the use of Bayesian Additive Regression Trees…

Methodology · Statistics 2020-01-22 Liangyuan Hu , Chenyang Gu , Michael Lopez , Jiayi Ji , Juan Wisnivesky

The research evaluates lightweight medical abstract classification methods to establish their maximum performance capabilities under financial budget restrictions. On the public medical abstracts corpus, we finetune BERT base and Distil…

Computation and Language · Computer Science 2025-10-22 Jiaqi Liu , Tong Wang , Su Liu , Xin Hu , Ran Tong , Lanruo Wang , Jiexi Xu

Large language model post-training relies on reinforcement learning to improve model capability and alignment quality. However, the off-policy training paradigm introduces distribution shift, which often pushes the policy beyond the trust…

Machine Learning · Computer Science 2026-04-24 Zhenpeng Su , Leiyu Pan , Minxuan Lv , Tiehua Mei , Zijia Lin , Yuntao Li , Wenping Hu , Ruiming Tang , Kun Gai , Guorui Zhou

Shortcuts to adiabatic expansion of the effectively one-dimensional Bose-Einstein condensate (BEC) loaded in the harmonic-oscillator (HO) trap is investigated by combining techniques of the variational approximation and inverse engineering.…

Quantum Physics · Physics 2020-05-26 Tang-You Huang , Boris A. Malomed , Xi Chen

The Escalator Boxcar Train (EBT) is a tool widely used in the study of balance laws motivated by structure population dynamics. This paper proves that the approximate solutions defined through the EBT converge to exact solutions. Moreover,…

Analysis of PDEs · Mathematics 2016-01-29 Rinaldo M. Colombo , Piotr Gwiazda , Magdalena Rosinska

In precision medicine, one of the most important problems is estimating the optimal individualized treatment rules (ITR), which typically involves recommending treatment decisions based on fully observed individual characteristics of…

Methodology · Statistics 2025-10-15 Yue Zhang , Shanshan Luo , Zhi Geng , Yangbo He

When data on treatment assignment, outcomes, and covariates from a randomized trial are available, a question of interest is to what extent covariates can be used to optimize treatment decisions. Statistical hypothesis testing of…

Applications · Statistics 2020-02-04 Mohsen Sadatsafavi , Mohammad Ali Mansournia , Paul Gustafson

Maximum entropy reinforcement learning (RL) methods have been successfully applied to a range of challenging sequential decision-making and control tasks. However, most of existing techniques are designed for discrete-time systems. As a…

Optimization and Control · Mathematics 2020-09-29 Jeongho Kim , Insoon Yang

This paper studies the estimation and inference of treatment effects in panel data settings when treatments change dynamically over time. We propose a balancing method that allows for (i) treatments to be assigned dynamically over time…

Econometrics · Economics 2026-02-24 Davide Viviano , Jelena Bradic

Causal inference is widely used in various fields, such as biology, psychology and economics, etc. In observational studies, we need to balance the covariates before estimating causal effect. This study extends the one-dimensional entropy…

Methodology · Statistics 2022-05-19 Juan Chen , Yingchun Zhou