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Reconstructing the unknown spectrum of a given X-ray source is a common problem in a wide range of X-ray imaging tasks. For high-energy sources, transmission measurements are mostly used to recover the X-ray spectrum, as a solution to an…

Applied Physics · Physics 2023-07-13 Arthur Walker , Alexandre Friou , Kevin Ginsburger

Objective: Quantitative technique based on In-line phase-contrast computed tomography with single scanning attracts more attention in application due to the flexibility of the implementation. However, the quantitative results usually suffer…

Medical Physics · Physics 2022-06-13 Suyu Liao , Shiwo Deng , Yining Zhu , Huitao Zhang , Peiping Zhu , Kai Zhang , Xing Zhao

Dual-energy computed tomography (DECT) has been widely used in many applications that need material decomposition. Image-domain methods directly decompose material images from high- and low-energy attenuation images, and thus, are…

Image and Video Processing · Electrical Eng. & Systems 2022-01-25 Zhipeng Li , Yong Long , Il Yong Chun

Background: Dual-energy imaging on cone-beam CT (CBCT) scanners has great potential in different clinical applications, including image-guided surgery and adaptive proton therapy. However, the clinical practice of dual-energy CBCT (DE-CBCT)…

Computed tomography (CT) imaging of the thorax is widely used for the detection and monitoring of pulmonary embolism (PE). However, CT images can contain artifacts due to the acquisition or the processes involved in image reconstruction.…

Existing Masked Image Modeling (MIM) depends on a spatial patch-based masking-reconstruction strategy to perceive objects'features from unlabeled images, which may face two limitations when applied to chest CT: 1) inefficient feature…

Image and Video Processing · Electrical Eng. & Systems 2024-07-15 Jie Zheng , Ru Wen , Haiqin Hu , Lina Wei , Kui Su , Wei Chen , Chen Liu , Jun Wang

Inferior soft-tissue contrast resolution is a major limitation of current CT scanners. The aim of the study is to improve the contrast resolution of CT scanners using dual-energy acquisition. Based on dual-energy material decomposition, the…

Medical Physics · Physics 2016-11-15 Wei Zhao , Lu Wan , Bo Zhang , Qiude Zhang , Tianye Niu

Imaging with multiple modalities or multiple channels is becoming increasingly important for our modern society. A key tool for understanding and early diagnosis of cancer and dementia is PET-MR, a combined positron emission tomography and…

Image and Video Processing · Electrical Eng. & Systems 2020-07-24 Matthias J. Ehrhardt

Photo-acoustic Tomography (PAT) and Thermo-acoustic Tomography (TAT) are medical imaging modalities that combine the high contrast of radiative properties of tissues with the high resolution of ultrasound. In both modalities, a first step…

Medical Physics · Physics 2012-02-15 Guillaume Bal

Background: Dual-energy CT (DECT) and material decomposition play vital roles in quantitative medical imaging. However, the decomposition process may suffer from significant noise amplification, leading to severely degraded image…

Multi-Cancer Early Detection (MCED) testing with tissue localization aims to detect and identify multiple cancer types from a single blood sample. Such tests have the potential to aid clinical decisions and significantly improve health…

Methodology · Statistics 2025-05-28 A. Gregory DiRienzo , Elie Massaad , Hutan Ashrafian

Material decomposition for imaging multiple contrast agents in a single acquisition has been made possible by spectral CT: a modality which incorporates multiple photon energy spectral sensitivities into a single data collection. This work…

Medical Physics · Physics 2020-08-11 Matthew Tivnan , Steven Tilley , J. Webster Stayman

In a standard computed tomography (CT) image, pixels having the same Hounsfield Units (HU) can correspond to different materials and it is, therefore, challenging to differentiate and quantify materials. Dual-energy CT (DECT) is desirable…

Medical Physics · Physics 2019-11-01 Wei Zhao , Tianling Lv , Peng Gao , Liyue Shen , Xianjin Dai , Kai Cheng , Mengyu Jia , Yang Chen , Lei Xing

We introduce the EMC algorithm for reconstructing a particle's 3D diffraction intensity from very many photon shot-noise limited 2D measurements, when the particle orientation in each measurement is unknown. The algorithm combines a…

Data Analysis, Statistics and Probability · Physics 2010-03-04 Duane Ne-Te Loh , Veit Elser

Background: Limited-angle (LA) dual-energy (DE) cone-beam CT (CBCT) is considered as a potential solution to achieve fast and low-dose DE imaging on current CBCT scanners without hardware modification. However, its clinical implementations…

Sparse-view computed tomography (CT) has been adopted as an important technique for speeding up data acquisition and decreasing radiation dose. However, due to the lack of sufficient projection data, the reconstructed CT images often…

Image and Video Processing · Electrical Eng. & Systems 2023-06-27 Hong Wang , Minghao Zhou , Dong Wei , Yuexiang Li , Yefeng Zheng

Spectral computed tomography (CT) has attracted much attention in radiation dose reduction, metal artifacts removal, tissue quantification and material discrimination. The x-ray energy spectrum is divided into several bins, each…

Image and Video Processing · Electrical Eng. & Systems 2021-08-26 Weiwen Wu , Dianlin Hu , Chuang Niu , Lieza Vanden Broeke , Anthony P. H. Butler , Peng Cao , James Atlas , Alexander Chernoglazov , Varut Vardhanabhuti , Ge Wang

Purpose: The goal is to provide a sufficient condition on the invertibility of a multi-energy (ME) X-ray transform. The energy-dependent X-ray attenuation profiles can be represented by a set of coefficients using the Alvarez-Macovski (AM)…

Medical Physics · Physics 2021-10-13 Yijun Ding , Eric W. Clarkson , Amit Ashok

Purpose: The main purpose of this study was to assess the reliability of shape and heterogeneity features in both Positron Emission Tomography (PET) and low-dose Computed Tomography (CT) components of PET/CT. A secondary objective was to…

Computer Vision and Pattern Recognition · Computer Science 2016-10-06 Marie-Charlotte Desseroit , Florent Tixier , Wolfgang Weber , Barry A Siegel , Catherine Cheze Le Rest , Dimitris Visvikis , Mathieu Hatt

Photon-counting computed tomography (PCCT) with energy discrimination capabilities hold great potentials to improve the limitations of the conventional CT, including better signal-to-noise ratio (SNR), improved contrast-to-noise ratio…

Medical Physics · Physics 2019-02-12 Xu Dong , Olga V. Pen , Zhicheng Zhang , Guohua Cao