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Medical artificial intelligence (AI) is revolutionizing the interpretation of chest X-ray (CXR) images by providing robust tools for disease diagnosis. However, the effectiveness of these AI models is often limited by their reliance on…

Image and Video Processing · Electrical Eng. & Systems 2024-10-14 Lijian Xu , Ziyu Ni , Hao Sun , Hongsheng Li , Shaoting Zhang

Recent developments in AI have provided assisting tools to support pathologists' diagnoses. However, it remains challenging to incorporate such tools into pathologists' practice; one main concern is AI's insufficient workflow integration…

Advances in computing power, deep learning architectures, and expert labelled datasets have spurred the development of medical imaging artificial intelligence systems that rival clinical experts in a variety of scenarios. The National…

Image and Video Processing · Electrical Eng. & Systems 2021-11-18 Rohan Shad , John P. Cunningham , Euan A. Ashley , Curtis P. Langlotz , William Hiesinger

The unprecedented performance of machine learning models in recent years, particularly Deep Learning and transformer models, has resulted in their application in various domains such as finance, healthcare, and education. However, the…

Human-Computer Interaction · Computer Science 2023-12-20 Milad Rogha

The translation of artificial intelligence (AI) systems into clinical practice requires bridging fundamental gaps between explainable AI theory, clinician expectations, and governance requirements. While conceptual frameworks define what…

Computers and Society · Computer Science 2025-11-05 Alexander Bakumenko , Aaron J. Masino , Janine Hoelscher

Physicians are--and feel--ethically, professionally, and legally responsible for patient outcomes, buffering patients from harmful AI determinations from medical AI systems. Many have called for explainable AI (XAI) systems to help…

Human-Computer Interaction · Computer Science 2025-07-23 Gennie Mansi , Mark Riedl

Despite the promises of data-driven artificial intelligence (AI), little is known about how we can bridge the gulf between traditional physician-driven diagnosis and a plausible future of medicine automated by AI. Specifically, how can we…

Human-Computer Interaction · Computer Science 2021-02-12 Hongyan Gu , Jingbin Huang , Lauren Hung , Xiang 'Anthony' Chen

The astounding success made by artificial intelligence (AI) in healthcare and other fields proves that AI can achieve human-like performance. However, success always comes with challenges. Deep learning algorithms are data-dependent and…

Image and Video Processing · Electrical Eng. & Systems 2021-06-25 Johann Li , Guangming Zhu , Cong Hua , Mingtao Feng , BasheerBennamoun , Ping Li , Xiaoyuan Lu , Juan Song , Peiyi Shen , Xu Xu , Lin Mei , Liang Zhang , Syed Afaq Ali Shah , Mohammed Bennamoun

AI-driven models have demonstrated significant potential in automating radiology report generation for chest X-rays. However, there is no standardized benchmark for objectively evaluating their performance. To address this, we present…

Computer Vision and Pattern Recognition · Computer Science 2024-11-25 Xiaoman Zhang , Hong-Yu Zhou , Xiaoli Yang , Oishi Banerjee , Julián N. Acosta , Josh Miller , Ouwen Huang , Pranav Rajpurkar

The development of AI-based methods to analyze radiology reports could lead to significant advances in medical diagnosis, from improving diagnostic accuracy to enhancing efficiency and reducing workload. However, the lack of…

Computation and Language · Computer Science 2025-08-14 Yuyan Ge , Kwan Ho Ryan Chan , Pablo Messina , René Vidal

Last years have been characterized by an upsurge of opaque automatic decision support systems, such as Deep Neural Networks (DNNs). Although they have great generalization and prediction skills, their functioning does not allow obtaining…

Automated diagnostic assistants in healthcare necessitate accurate AI models that can be trained with limited labeled data, can cope with severe class imbalances and can support simultaneous prediction of multiple disease conditions. To…

Computer Vision and Pattern Recognition · Computer Science 2021-02-11 Deepta Rajan , Jayaraman J. Thiagarajan , Alexandros Karargyris , Satyananda Kashyap

Objective. This paper presents an overview of generalizable and explainable artificial intelligence (XAI) in deep learning (DL) for medical imaging, aimed at addressing the urgent need for transparency and explainability in clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-03-12 Ahmad Chaddad , Yan Hu , Yihang Wu , Binbin Wen , Reem Kateb

Clinical deployment of deep learning algorithms for chest x-ray interpretation requires a solution that can integrate into the vast spectrum of clinical workflows across the world. An appealing approach to scaled deployment is to leverage…

Despite the fact that Artificial Intelligence (AI) has boosted the achievement of remarkable results across numerous data analysis tasks, however, this is typically accompanied by a significant shortcoming in the exhibited transparency and…

Artificial intelligence (AI) generally and machine learning (ML) specifically demonstrate impressive practical success in many different application domains, e.g. in autonomous driving, speech recognition, or recommender systems. Deep…

Artificial Intelligence · Computer Science 2018-01-02 Andreas Holzinger , Chris Biemann , Constantinos S. Pattichis , Douglas B. Kell

Pediatric heart diseases present a broad spectrum of congenital and acquired diseases. More complex congenital malformations require a differentiated and multimodal decision-making process, usually including echocardiography as a central…

Artificial Intelligence · Computer Science 2025-03-31 Mohammed Yaseen Jabarulla , Theodor Uden , Thomas Jack , Philipp Beerbaum , Steffen Oeltze-Jafra

A surge of interest in explainable AI (XAI) has led to a vast collection of algorithmic work on the topic. While many recognize the necessity to incorporate explainability features in AI systems, how to address real-world user needs for…

Human-Computer Interaction · Computer Science 2021-09-07 Q. Vera Liao , Daniel Gruen , Sarah Miller

Despite promising developments in Explainable Artificial Intelligence, the practical value of XAI methods remains under-explored and insufficiently validated in real-world settings. Robust and context-aware evaluation is essential, not only…

Human-Computer Interaction · Computer Science 2025-06-18 Ivania Donoso-Guzmán , Kristýna Sirka Kacafírková , Maxwell Szymanski , An Jacobs , Denis Parra , Katrien Verbert

As systems based on opaque Artificial Intelligence (AI) continue to flourish in diverse real-world applications, understanding these black box models has become paramount. In response, Explainable AI (XAI) has emerged as a field of research…

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