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Blood vessel networks in the brain play a crucial role in stroke research, where understanding their topology is essential for analyzing blood flow dynamics. However, extracting detailed topological vessel network information from…

Computer Vision and Pattern Recognition · Computer Science 2025-04-17 Joël Mathys , Andreas Plesner , Jorel Elmiger , Roger Wattenhofer

Computational fluid dynamics (CFD) models are emerging as tools for assisting in diagnostic assessment of cardiovascular disease. Recent advances in image segmentation has made subject-specific modelling of the cardiovascular system a…

Quantitative Methods · Quantitative Biology 2021-01-18 Mitchel J. Colebank , L. Mihaela Paun , M. Umar Qureshi , Naomi Chesler , Dirk Husmeier , Mette S. Olufsen , Laura Ellwein Fix

Phase-contrast magnetic resonance imaging (MRI) provides time-resolved quantification of blood flow dynamics that can aid clinical diagnosis. Long in vivo scan times due to repeated three-dimensional (3D) volume sampling over cardiac phases…

Image and Video Processing · Electrical Eng. & Systems 2020-04-22 Valery Vishnevskiy , Jonas Walheim , Sebastian Kozerke

Diffuse correlation spectroscopy (DCS) analyzes the autocorrelation function of photons scattered by red blood cells, enabling non-invasive, continuous measurement of deep tissue blood flow at the bedside. Multi-layer DCS models (two- and…

The glow of a starry night sky, the smell of a freshly brewed cup of coffee or the sound of ocean waves breaking on the beach are representations of the physical world that have been created by the dynamic interactions of thousands of…

Neurons and Cognition · Quantitative Biology 2011-07-28 Henry Lütcke , Fritjof Helmchen

Segmenting of clinically important retinal blood vessels into arteries and veins is a prerequisite for retinal vessel analysis. Such analysis can provide potential insights and bio-markers for identifying and diagnosing various retinal eye…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Sharan SK , Subin Sahayam , Umarani Jayaraman , Lakshmi Priya A

The precise delineation of blood vessels in medical images is critical for many clinical applications, including pathology detection and surgical planning. However, fully-automated vascular segmentation is challenging because of the…

Image and Video Processing · Electrical Eng. & Systems 2024-09-20 Amine Sadikine , Bogdan Badic , Enzo Ferrante , Vincent Noblet , Pascal Ballet , Dimitris Visvikis , Pierre-Henri Conze

Deep learning approaches may help radiologists in the early diagnosis and timely treatment of cerebrovascular diseases. Accurate cerebral vessel segmentation of Time-of-Flight Magnetic Resonance Angiographs (TOF-MRAs) is an essential step…

Image and Video Processing · Electrical Eng. & Systems 2021-01-25 V. de Vos , K. M. Timmins , I. C. van der Schaaf , Y. Ruigrok , B. K. Velthuis , H. J. Kuijf

In this study, we develop a novel methodology for annotating the brain vasculature using dynamic 4D-CTA head scans. By using multiple time points from dynamic CTA acquisitions, we subtract bone and soft tissue to enhance the visualization…

Computer Vision and Pattern Recognition · Computer Science 2026-02-06 Alberto Mario Ceballos-Arroyo , Shrikanth M. Yadav , Chu-Hsuan Lin , Jisoo Kim , Geoffrey S. Young , Lei Qin , Huaizu Jiang

The role of brain hemodynamics in neurodegenerative diseases cannot be fully assessed using existing imaging technologies. Recently, 2D Dynamic Ultrasound Localization Microscopy (DULM) has allowed for the quantitative mapping of the…

There has been a consistent growth in research involving imaging of microvasculature over the past few decades. By 2008, publications mentioning the microcirculation had grown more than 2000 per annum. Many techniques have been demonstrated…

Medical Physics · Physics 2019-07-04 Cerine Lal , Martin J Leahy

Automatic blood vessel segmentation from retinal images plays an important role in the diagnosis of many systemic and eye diseases, including retinopathy of prematurity. Current state-of-the-art research in blood vessel segmentation from…

Image and Video Processing · Electrical Eng. & Systems 2023-06-21 Gorana Gojić , Veljko Petrović , Radovan Turović , Dinu Dragan , Ana Oros , Dušan Gajić , Nebojša Horvat

Automated in-vitro cell detection and counting have been a key theme for artificial and intelligent biological analysis such as biopsy, drug analysis and decease diagnosis. Along with the rapid development of microfluidics and lab-on-chip…

Computer Vision and Pattern Recognition · Computer Science 2020-01-08 Tiancheng Xia , Richard Jiang , YongQing Fu , Nanlin Jin

Vasculature is known to be of key biological significance, especially in the study of cancer. As such, considerable effort has been focused on the automated measurement and analysis of vasculature in medical and pre-clinical images. In…

Computer Vision and Pattern Recognition · Computer Science 2017-05-29 Russell Bates , Benjamin Irving , Bostjan Markelc , Jakob Kaeppler , Ruth Muschel , Vicente Grau , Julia A. Schnabel

Cerebral aneurysms and arteriovenous malformations are life-threatening hemodynamic pathologies of the brain. While surgical intervention is often essential to prevent fatal outcomes, it carries significant risks both during the procedure…

Machine Learning · Computer Science 2026-03-17 Irem Topal , Alexander Cherevko , Yuri Bugay , Maxim Shishlenin , Jean Barbier , Deniz Eroglu , Édgar Roldán , Roman Belousov

Fluorescence microscopes can record the dynamics of living cells with high spatio-temporal resolution in a single plane. However, monitoring rapid and dim fluorescence fluctuations, e.g induced by neuronal activity in the brain, remains…

Morphology of cardiovascular tissue is influenced by the unsteady behavior of the blood flow and vice versa. Therefore, the pathogenesis of several cardiovascular diseases is directly affected by the blood-flow dynamics. Understanding flow…

4D Flow Magnetic Resonance Imaging (4D Flow MRI) is a non-invasive technique for volumetric, time-resolved blood flow quantification. However, apparent trade-offs between acquisition time, image noise, and resolution limit clinical…

A number of questions in systems biology such as understanding how dynamics of neuronal networks are related to brain function require the ability to capture the functional dynamics of large cellular populations at high speed. Recently,…

Dynamic medical imaging is usually limited in application due to the large radiation doses and longer image scanning and reconstruction times. Existing methods attempt to reduce the dynamic sequence by interpolating the volumes between the…

Computer Vision and Pattern Recognition · Computer Science 2020-04-28 Yuyu Guo , Lei Bi , Euijoon Ahn , Dagan Feng , Qian Wang , Jinman Kim