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A work recently published experimentally demonstrates an increase in the radiobiological efficacy of clinical proton beams when a tumour is treated in the presence of a concentration of 11B. The paper, for the first time, demonstrates the…

We report the first investigation of relativistic effects on the UV-vis spectra of two prototype complexes for so-called photo-activated chemotherapy (PACT), trans-trans-trans-[Pt(N3)2(OH)2(NH3)2] and cis-trans-cis-[Pt(N3)2(OH)2(NH3)2].In…

Chemical Physics · Physics 2020-12-30 Joel Creutzberg , Erik Donovan Hedegård

Purpose: A Monte Carlo (MC) beam model and its implementation in a clinical treatment planning system (TPS, Varian Eclipse) are presented for a modified ultra-high dose-rate electron FLASH radiotherapy (eFLASH-RT) LINAC. Methods: The gantry…

A non-relativistic, charged-particle beam is placed into a crossed magnetic field. For such a system, the nonlinear electrostatic oscillations generation in the different degrees of the beam freedom may be triggered by the energy/momentum…

Plasma Physics · Physics 2019-07-03 A. R. Karimov , A. M. Bulygin , P. A. Murad

Objective: Research on eye lens dosimetry for radiation workers has increased after the 2012 ICRP118 update on eye lens dose limits. However, corneal dosimetry remains underexplored due to historical focus and measurement challenges. This…

Medical Physics · Physics 2025-09-26 Zahra Akbari Khanaposhtani , Hossein Rajabi

Charge Transfer (CT) has enjoyed continuous interest due to increasing experimental control over molecular structure leading to applications in, for example, photovoltaics and hydrogen production. In this paper, we investigate the effect of…

Chemical Physics · Physics 2022-06-29 Marìck Manrho , Thomas L. C. Jansen , Jasper Knoester

The high-luminosity requirement in future lepton colliders imposes a need for a high-intensity positron source. In the conventional scheme, positron beams are obtained by the conversion of bremsstrahlung photons into electron-positron pairs…

In the past two decades, laser-accelerated ion sources and their applications have been intensely researched. Recently, it has been shown through experiments that proton beams with characteristics comparable to those obtained with solid…

Plasma Physics · Physics 2018-04-20 Dragos Tatomirescu , Daniel Vizman , Emmanuel d'Humières

We consider a model of boosted dark matter (DM), where a fraction of DM is upscattered to relativistic energies by cosmic ray electrons. Such interactions responsible for boosting the DM also attenuate its flux at the Earth. Considering a…

High Energy Physics - Phenomenology · Physics 2025-01-24 Tim Herbermann , Manfred Lindner , Manibrata Sen

Stimulated Brillouin backscattering of light is shown to be drastically enhanced in electron-positron plasmas, in contrast to the suppression of stimulated Raman scattering. A generalized theory of three-wave coupling between…

Plasma Physics · Physics 2016-01-13 Matthew R. Edwards , Nathaniel J. Fisch , Julia M. Mikhailova

A dielectric-loaded linac powered by THz-pulses is one of the key parts of the "Attosecond X-ray Science: Imaging and Spectroscopy" (AXSIS) project at DESY, Hamburg. As in conventional accelerators, the AXSIS linac is designed to have phase…

Accelerator Physics · Physics 2018-12-26 K. Galaydych , R. Assmann , U. Dorda , B. Marchetti , G. Vashchenko , I. Zagorodnov

In this dissertation, a fully object-oriented, fully relativistic, multi-dimensional Particle-In-Cell code was developed and applied to answer key questions in plasma-based accelerator research. The simulations increase the understanding of…

Computational Physics · Physics 2015-03-03 Roy G. Hemker

Direct laser acceleration has proven to be an efficient source of high-charge electron bunches and high brilliance X-rays. However, an analytical description of the acceleration in the interaction with varying plasma density targets is…

Plasma Physics · Physics 2024-12-19 Robert Babjak , Bertrand Martinez , Miroslav Krus , Marija Vranic

Photoassociation, assembling molecules from atoms using laser light, is limited by the low density of atom pairs at sufficiently short interatomic separations. Here, we show that non-resonant light with intensities of the order of 10^10…

Atomic Physics · Physics 2013-01-08 Rosario González-Férez , Christiane P. Koch

In order to study the dynamic response of the material and the physical mechanism of the fluid dynamics, an accelerator scenario which can be applied to hard X-ray free electron laser and high energy electron radiography was proposed. This…

The collisional thick target model (CTTM) of solar hard X-ray (HXR) bursts has become an almost 'Standard Model' of flare impulsive phase energy transport and radiation. However, it faces various problems in the light of recent data,…

Solar and Stellar Astrophysics · Physics 2015-05-14 J. C. Brown , R. Turkmani , E. P. Kontar , A. L. MacKinnon , L. Vlahos

A design for a compact x-ray light source (CXLS) with flux and brilliance orders of magnitude beyond existing laboratory scale sources is presented. The source is based on inverse Compton scattering of a high brightness electron bunch on a…

Radiotherapy is one of the main methods in the successful treatment of cancer. The tumor is irradiated with photons or charged particles (e.g. protons), and in the case of massive charged particles, the treatment results in less unnecessary…

Medical Physics · Physics 2019-03-20 Monika Varga-Kofarago

We used the GEANT4 Monte Carlo MC Toolkit to simulate carbon ion beams incident on water, tissue, and bone, taking into account nuclear fragmentation reactions. Upon increasing the energy of the primary beam, the position of the Bragg-Peak…

Medical Physics · Physics 2021-02-26 M. Kh. Hamad

Accurate dose calculation is vitally important for proton therapy. Pencil beam (PB) model-based dose calculation is fast but inaccurate due to the approximation when dealing with inhomogeneities. Monte Carlo (MC) dose calculation is the…