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The vast majority of semantic segmentation approaches rely on pixel-level annotations that are tedious and time consuming to obtain and suffer from significant inter and intra-expert variability. To address these issues, recent approaches…

Cell detection in histopathology images is of great interest to clinical practice and research, and convolutional neural networks (CNNs) have achieved remarkable cell detection results. Typically, to train CNN-based cell detection models,…

Computer Vision and Pattern Recognition · Computer Science 2023-02-17 Zipei Zhao , Fengqian Pang , Yaou Liu , Zhiwen Liu , Chuyang Ye

Histopathology images; microscopy images of stained tissue biopsies contain fundamental prognostic information that forms the foundation of pathological analysis and diagnostic medicine. However, diagnostics from histopathology images…

Computer Vision and Pattern Recognition · Computer Science 2019-10-30 Aïcha BenTaieb , Ghassan Hamarneh

Deep learning classifiers for characterization of whole slide tissue morphology require large volumes of annotated data to learn variations across different tissue and cancer types. As is well known, manual generation of digital pathology…

Image and Video Processing · Electrical Eng. & Systems 2019-07-10 Shahira Abousamra , Le Hou , Rajarsi Gupta , Chao Chen , Dimitris Samaras , Tahsin Kurc , Rebecca Batiste , Tianhao Zhao , Shroyer Kenneth , Joel Saltz

Deep learning-based diagnostic performance increases with more annotated data, but large-scale manual annotations are expensive and labour-intensive. Experts evaluate diagnostic images during clinical routine, and write their findings in…

Image and Video Processing · Electrical Eng. & Systems 2024-07-01 Joeran S. Bosma , Anindo Saha , Matin Hosseinzadeh , Ilse Slootweg , Maarten de Rooij , Henkjan Huisman

Current deep learning paradigms largely benefit from the tremendous amount of annotated data. However, the quality of the annotations often varies among labelers. Multi-observer studies have been conducted to study these annotation…

Computer Vision and Pattern Recognition · Computer Science 2020-10-05 Xiaosong Wang , Ziyue Xu , Dong Yang , Leo Tam , Holger Roth , Daguang Xu

As the area of application of deep neural networks expands to areas requiring expertise, e.g., in medicine and law, more exquisite annotation processes for expert knowledge training are required. In particular, it is difficult to guarantee…

Computer Vision and Pattern Recognition · Computer Science 2021-10-25 Seungbum Hong , Jiwon Lee , Bokyung Park , Ahmed A. Alwusaibie , Anwar H. Alfadhel , SungHyun Park , Woo Jin Hyung , Min-Kook Choi

Annotating medical imaging datasets is costly, so fine-tuning (or transfer learning) is the most effective method for digital pathology vision applications such as disease classification and semantic segmentation. However, due to texture…

Computer Vision and Pattern Recognition · Computer Science 2023-08-23 Tushar Kataria , Beatrice Knudsen , Shireen Elhabian

Deep convolutional neural networks have driven substantial advancements in the automatic understanding of images. Requiring a large collection of images and their associated annotations is one of the main bottlenecks limiting the adoption…

Computer Vision and Pattern Recognition · Computer Science 2019-08-22 Zahra Mirikharaji , Yiqi Yan , Ghassan Hamarneh

Deep learning methods have shown promise in classifying breast cancer histopathology images, but their performance often declines with limited annotated data, a critical challenge in medical imaging due to the high cost and expertise…

Computer Vision and Pattern Recognition · Computer Science 2025-05-08 Liu Suxing , Byungwon Min

Comprehensive surgical planning require complex patient-specific anatomical models. For instance, functional muskuloskeletal simulations necessitate all relevant structures to be segmented, which could be performed in real-time using deep…

Image and Video Processing · Electrical Eng. & Systems 2019-05-20 Firat Ozdemir , Orcun Goksel

Medical image annotation is a major hurdle for developing precise and robust machine learning models. Annotation is expensive, time-consuming, and often requires expert knowledge, particularly in the medical field. Here, we suggest using…

Computer Vision and Pattern Recognition · Computer Science 2020-09-28 Holger R Roth , Dong Yang , Ziyue Xu , Xiaosong Wang , Daguang Xu

Understanding a surgical scene is crucial for computer-assisted surgery systems to provide any intelligent assistance functionality. One way of achieving this scene understanding is via scene segmentation, where every pixel of a frame is…

Computer Vision and Pattern Recognition · Computer Science 2024-04-08 Alexander C. Jenke , Sebastian Bodenstedt , Fiona R. Kolbinger , Marius Distler , Jürgen Weitz , Stefanie Speidel

Though analysis of Medical Images by Deep Learning achieves unprecedented results across various applications, the effect of \emph{noisy training annotations} is rarely studied in a systematic manner. In Medical Image Analysis, most reports…

Computer Vision and Pattern Recognition · Computer Science 2018-06-21 David Kügler , Anirban Mukhopadhyay

Annotating cancerous regions in whole-slide images (WSIs) of pathology samples plays a critical role in clinical diagnosis, biomedical research, and machine learning algorithms development. However, generating exhaustive and accurate…

Computer Vision and Pattern Recognition · Computer Science 2022-06-09 Zhenzhen Wang , Carla Saoud , Sintawat Wangsiricharoen , Aaron W. James , Aleksander S. Popel , Jeremias Sulam

Image collections, if critical aspects of image content are exposed, can spur research and practical applications in many domains. Supervised machine learning may be the only feasible way to annotate very large collections, but leading…

Computer Vision and Pattern Recognition · Computer Science 2019-03-01 Sara Mousavi , Ramin Nabati , Megan Kleeschulte , Audris Mockus

Recently deep neural networks, which require a large amount of annotated samples, have been widely applied in nuclei instance segmentation of H\&E stained pathology images. However, it is inefficient and unnecessary to label all pixels for…

Computer Vision and Pattern Recognition · Computer Science 2022-12-21 Wei Lou , Haofeng Li , Guanbin Li , Xiaoguang Han , Xiang Wan

Deep learning-based nuclei segmentation and classification in pathology images typically rely on large-scale pixel-level manual annotations, which are costly and difficult to obtain across diverse tissues and staining conditions. To address…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Kazuya Nishimura , Ryoma Bise , Haruka Hirose , Yasuhiro Kojima

To efficiently establish training databases for machine learning methods, collaborative and crowdsourcing platforms have been investigated to collectively tackle the annotation effort. However, when this concept is ported to the medical…

Computer Vision and Pattern Recognition · Computer Science 2017-08-22 Martin Rajchl , Lisa M. Koch , Christian Ledig , Jonathan Passerat-Palmbach , Kazunari Misawa , Kensaku Mori , Daniel Rueckert

Weak supervision learning on classification labels has demonstrated high performance in various tasks, while a few pixel-level fine annotations are also affordable. Naturally a question comes to us that whether the combination of…

Computer Vision and Pattern Recognition · Computer Science 2021-10-26 Jiahui Li , Wen Chen , Xiaodi Huang , Zhiqiang Hu , Qi Duan , Hongsheng Li , Dimitris N. Metaxas , Shaoting Zhang