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We show that under a certain non-cancellation condition the attenuated Radon transform uniquely determines piecewise constant attenuation $a$ and piecewise $C^2$ source density $f$ with jumps over real analytic boundaries possibly having…
The stochastic differential and integral equations describing the system of particles weakly interacting among themselves which are absorbed and scattered by particles of a medium are considered. The time-dependent transport equation with…
We study the problem of recovery both the attenuation $a$ and the source $f$ in the attenuated X-ray transform in the plane. We study the linearization as well. It turns out that there are natural Hamiltonian flow that determines which…
In positron emission tomography (PET), it is indispensable to perform attenuation correction in order to obtain the quantitatively accurate activity map (tracer distribution) in the body. Generally, this is carried out based on the…
A sparsity-exploiting algorithm intended for few-view Single Photon Emission Computed Tomography (SPECT) reconstruction is proposed and characterized. The algorithm models the object as piecewise constant subject to a blurring operation. To…
We study an inverse problem where an unknown radiating source is observed with collimated detectors along a single line and the medium has a known attenuation. The research is motivated by applications in SPECT and beam hardening. If…
A number of practically important imaging problems involve inverting the generalized Radon transform (GRT) $\mathcal R$ of a function $f$ in $\mathbb R^3$. On the other hand, not much is known about the spatial resolution of the…
We study the non-parametric estimation of a multidimensional unknown density f in a tomography problem based on independent and identically distributed observations, whose common density is proportional to the Radon transform of f. We…
Accurate quantification in positron emission tomography (PET) is essential for accurate diagnostic results and effective treatment tracking. A major issue encountered in PET imaging is attenuation. Attenuation refers to the diminution of…
Here we present new joint reconstruction and regularization techniques inspired by ideas in microlocal analysis and lambda tomography, for the simultaneous reconstruction of the attenuation coefficient and electron density from X-ray…
The single-scatter approximation is fundamental in many tomographic imaging problems including x-ray scatter imaging and optical scatter imaging for certain media. In all cases, noisy measurements are affected by both local scatter events…
Reconstructing an image from its Radon transform is a fundamental computed tomography (CT) task arising in applications such as X-ray scans. In many practical scenarios, a full 180-degree scan is not feasible, or there is a desire to reduce…
The photon emission from a single molecule driven simultaneously by a laser and a slow electric radio frequency (rf) field is studied. We use a non-Hermitian Hamiltonian approach which accounts for the radiative decay of a two level system…
In medical SPECT imaging, we seek to simultaneously obtain the internal radioactive sources and the attenuation map using not only ballistic measurements but also first order scattering measurements. The problem is modeled using the…
Single photon emission computed tomography (SPECT) is a well established clinical tool for functional imaging. A limitation of current SPECT systems is the use of mechanical collimation, where only a small fraction of the emitted photons is…
Fluorescence microscopy is of vital importance for understanding biological function. However most fluorescence experiments are only qualitative inasmuch as the absolute number of fluorescent particles can often not be determined.…
Attenuation correction (AC) is necessary for accurate activity quantification in positron emission tomography (PET). Conventional reconstruction methods typically rely on attenuation maps derived from a co-registered computed tomography…
Readout multiplexing is a promising solution to overcome hardware limitations and data bottlenecks in imaging with single-photon detectors. Conventional multiplexed readout processing creates an upper bound on photon counts at a very fine…
Tomographic investigations are a central tool in medical applications, allowing doctors to image the interior of patients. The corresponding measurement process is commonly modeled by the Radon transform. In practice, the solution of the…
We investigate the inverse source problem for the wave equation, arising in photo- and thermoacoustic tomography. There exist quite a few theoretically exact inversion formulas explicitly expressing solution of this problem in terms of the…