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Non-invasive optical manipulation of particles has emerged as a powerful and versatile tool for biological study and nanotechnology. In particular, trapping and rotation of cells, cell nuclei and sub-micron particles enables unique…

Actuating the acoustic resonance modes of a microfluidic device containing suspended particles (e.g., cells) allows for the manipulation of their individual positions. In this work, we investigate how the number of resonance modes $M$…

Applied Physics · Physics 2025-10-08 Guilherme Perticarari , Dongjun Wu , Thierry Baasch

Radiation forces and torques enable the manipulation of objects with acoustic and electromagnetic waves. Yet, harnessing them in complex scattering media remains a formidable challenge, especially when multiple objects must be controlled…

Conventional optical tweezers are generated by the intensity gradient of highly focused laser beams, but the requirement of strong intensity gradient limits the tunability of optical traps. Here we show a new type of optical tweezers with…

Optics · Physics 2019-12-03 Xionggui Tang , Fan Nan , Zijie Yan

We propose an experimental architecture where an array of optical tweezers affords site-dependent control over the confining potential of a conventional radio-frequency ion trap. The site-dependent control enables programmable manipulation…

Quantum Physics · Physics 2021-08-25 Yi Hong Teoh , Manas Sajjan , Zewen Sun , Fereshteh Rajabi , Rajibul Islam

Advances in laser and optoelectronic technologies brought the general concept of optomechanical manipulation to the level of standard biophysical tools, paving ways towards controlled experiments and measurements of tiny mechanical forces.…

Optics · Physics 2021-06-30 Ivan Shishkin , Hen Markovich , Yael Roichman , Pavel Ginzburg

Holographic Optical Tweezers (HOT) are powerful tools that can manipulate micro and nano-scale objects with high accuracy and precision. They are most commonly used for biological applications, such as cellular studies, and more recently,…

Systems and Control · Electrical Eng. & Systems 2024-04-29 Tommy Zhang , Nicole Werner , Ashis G. Banerjee

The ability to precisely trap, transport and manipulate micrometer-sized objects, including biological cells, DNA-coated microspheres and microorganisms, is very important in life science studies and biomedical applications. In this study,…

Fluid Dynamics · Physics 2012-07-05 Gan Yu , Xiaolin Chen , Jie Xu

Optical trapping describes the interaction between light and matter to manipulate micro-objects through momentum transfer. In the case of 3D trapping with a single beam, this is termed optical tweezers. Optical tweezers are a powerful and…

We demonstrate coaxial atomic force microscope (AFM) tweezers that can trap and place small objects using dielectrophoresis (DEP). An attractive force is generated at the tip of a coaxial AFM probe by applying a radio frequency voltage…

Instrumentation and Detectors · Physics 2015-05-18 K. A. Brown , J. A. Aguilar , R. M. Westervelt

We experimentally demonstrate stable trapping and controlled manipulation of silica microspheres in a structured optical beam consisting of a dark focus surrounded by light in all directions - the so-called Dark Focus Tweezer. Results from…

Optical tweezers are powerful tools for high resolution study of surface properties. Such experiments are traditionally performed by studying the active or the brownian fluctuation of trapped particles in the X, Y, Z direction. Here we find…

Optics · Physics 2018-11-13 Rahul Vaipully , Dhanush Bhatt , Anand Dev Ranjan , Basudev Roy

Optical tweezers confine a particle in an intensity-defined potential well by engaging its local multipoles. In this picture, eliminating far-field scattering from the particle should cancel the optical force, as the multipole moments…

Whispering gallery mode microlasers are known for their high Q-factors, characteristic emission spectra and sensitivity to local refractive index changes. This sensitivity combined with the ability of various cell types to internalise these…

Optical and acoustical trapping has been established as a tool for holding and moving microscopic particles suspended in a liquid in a contact-free and non-invasive manner. Opposed to standard microscopic imaging where the probe is fixated,…

Numerical Analysis · Mathematics 2025-10-27 Peter Elbau , Monika Ritsch-Marte , Otmar Scherzer , Denise Schmutz

Optical trapping, also known as optical tweezing or optical levitation, is a technique that uses highly focused laser beams to manipulate micro- and nanoscopic particles. In optical traps driven by high-energy pulses, material non-linearity…

Acoustic levitation enables non-contact manipulation using sound waves. While conventional methods entrap particles at pressure nodes (zero-pressure region surrounded by high-pressure), we demonstrate stable acoustic levitation and…

We propose a novel way to trap and manipulate nano-objects above a dielectric substrate using an apertureless near-field probe. A combination of evanescent illumination and light scattering at the probe apex is used to shape the optical…

Optics · Physics 2009-11-10 Patrick C. Chaumet , Adel Rahmani , Manuel Nieto-Vesperinas

Combining optical tweezers with fluorescence microscopy is a powerful tool for single-cell analysis, playing a pivotal role in disease diagnosis, cell sorting, and the investigation of cellular dynamics. However, fluorescence detection…

Optics · Physics 2026-04-07 Jun Yin , Sanyou Chen , Yihao Yan , Mengqi Wang , Ya Wang , Yiheng Lin , Qi Zhang , Fazhan Shi

Since their invention in the 1980s [1], optical tweezers have found a wide range of applications, from biophotonics and mechanobiology to microscopy and optomechanics [2, 3, 4, 5]. Simulations of the motion of microscopic particles held by…