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Conformation generation, also known as molecular unfolding (MU), is a crucial step in structure-based drug design, remaining a challenging combinatorial optimization problem. Quantum annealing (QA) has shown great potential for solving…

We evaluate the application of quantum annealing (QA) to a real-world combinatorial optimisation problem-room scheduling for sports camps at the Australian Institute of Sport-using both classical and quantum approaches. Due to current…

Quantum Physics · Physics 2025-09-08 Krzysztof Giergiel , Y. Sam Yang , Anthony B. Murphy

Energy efficient routing in wireless sensor networks has attracted attention from researchers in both academia and industry, most recently motivated by the opportunity to use SDN (software defined network)-inspired approaches. These…

Emerging Technologies · Computer Science 2022-12-02 Jie Chen , Prasanna Date , Nicholas Chancellor , Mohammed Atiquzzaman , Cormac Sreenan

Combinatorial optimization is anticipated to be one of the primary use cases for quantum computation in the coming years. The Quantum Approximate Optimization Algorithm (QAOA) and Quantum Annealing (QA) can potentially demonstrate…

Quantum annealing is a method developed to solve combinatorial optimization problems by utilizing quantum bits. Solving such problems corresponds to minimizing a cost function defined over binary variables. However, in many practical cases,…

Quantum Physics · Physics 2025-06-26 Seiya Endo , Shohei Kawakatsu , Hiromichi Matsuyama , Kohei Suzuki , Yuichiro Matsuzaki

Quantum Annealers (QAs) operate as single-instruction machines, lacking a SWAP operation to overcome limited qubit connectivity. Consequently, multiple physical qubits are chained to form a program qubit with higher connectivity, resulting…

Quantum Physics · Physics 2023-12-04 Ramin Ayanzadeh , Moinuddin Qureshi

Quantum annealing is a promising heuristic method to solve combinatorial optimization problems, and efforts to quantify performance on real-world problems provide insights into how this approach may be best used in practice. We investigate…

Quantum Physics · Physics 2023-09-07 Kazuki Ikeda , Yuma Nakamura , Travis S. Humble

Quantum computing is rapidly advancing, harnessing the power of qubits' superposition and entanglement for computational advantages over classical systems. However, scalability poses a primary challenge for these machines. By implementing a…

We present a comparison study of state-of-the-art classical optimisation methods to a D-Wave 2000Q quantum annealer for the planning of Earth observation missions. The problem is to acquire high value images while obeying the attitude…

We study algorithms inspired by quantum annealing that are suited for the NISQ era. First, we analyze approximate quantum annealing (AQA), which employs a discretized annealing ansatz in which the time step and the number of layers are…

Quantum Physics · Physics 2026-04-29 Rijul Sachdeva , Vrinda Mehta , Manpreet Singh Jattana , Kristel Michielsen , Fengping Jin

Active user detection in a non-orthogonal multiple access (NOMA) network is a major challenge for 5G/6G applications. However, classical algorithms that can perform this task suffer either from complexity or reduced performances. This work…

Signal Processing · Electrical Eng. & Systems 2024-08-01 Romain Piron , Claire Goursaud

The use of 1-bit analog-to-digital converters (ADCs) is seen as a promising approach to significantly reduce the power consumption and hardware cost of multiple-input multiple-output (MIMO) receivers. However, the nonlinear distortion due…

Information Theory · Computer Science 2022-10-12 Neil Irwin Bernardo , Jingge Zhu , Yonina C. Eldar , Jamie Evans

Quantum Random Access Memory (QRAM) is a critical component for loading classical data into quantum computers. While constructing a practical QRAM presents several challenges, including the impracticality of an infinitely large QRAM size…

Quadratic unconstrained binary optimization (QUBO) is a field of operations research that is attracting growing interest due to the recent availability of quantum hardware targeted at solving QUBO problems. However, practical adoption is…

Software Engineering · Computer Science 2026-01-22 Lodovica Marchesi , Amal Nasharti , Michele Marchesi

The recent availability of quantum annealers as cloud-based services has enabled new ways to handle machine learning problems, and several relevant algorithms have been adapted to run on these devices. In a recent work, linear regression…

Quantum Physics · Physics 2025-03-18 Costantino Carugno , Maurizio Ferrari Dacrema , Paolo Cremonesi

Base stations in 5G and beyond use advanced antenna systems (AASs), where multiple passive antenna elements and radio units are integrated into a single box. A critical bottleneck of such a system is the digital fronthaul between the AAS…

Signal Processing · Electrical Eng. & Systems 2022-02-21 Yasaman Khorsandmanesh , Emil Björnson , Joakim Jaldèn

Using a specially constructed set of hard 2-SAT problems with four satisfying assignments, we study the scaling and sampling performance of numerical simulation of quantum annealing as well as that of the physical quantum annealers offered…

Quantum Physics · Physics 2025-11-04 Vrinda Mehta , Hans De Raedt , Kristel Michielsen , Fengping Jin

Quantum computing has long promised to revolutionize the way we solve complex problems. At the same time, tensor networks are widely used across various fields due to their computational efficiency and capacity to represent intricate…

Quantum Physics · Physics 2024-12-10 Miquel Albertí Binimelis

Overcoming the conventional trade-off between throughput and bit error rate (BER) performance, versus computational complexity is a long-term challenge for uplink Multiple-Input Multiple-Output (MIMO) detection in base station design for…

Networking and Internet Architecture · Computer Science 2021-03-22 Minsung Kim , Salvatore Mandrà , Davide Venturelli , Kyle Jamieson

Quantum algorithm design usually assumes access to a perfect quantum computer with ideal properties like full connectivity, noise-freedom and arbitrarily long coherence time. In Noisy Intermediate-Scale Quantum (NISQ) devices, however, the…

Quantum Physics · Physics 2020-09-11 Xiangzhen Zhou , Sanjiang Li , Yuan Feng
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