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Constrained combinatorial optimization problems are frequently reformulated as quadratic unconstrained binary optimization (QUBO) models in order to leverage emerging quantum optimization algorithms such as the Variational Quantum…

Quantum Physics · Physics 2026-04-23 Xin Wei Lee , Hoong Chuin Lau

In this paper we present a novel strategy to solve optimization problems within a hybrid quantum-classical scheme based on quantum annealing, with a particular focus on QUBO problems. The proposed algorithm is based on an iterative…

Quantum Physics · Physics 2020-04-07 Enrico Blanzieri , Davide Pastorello

In recent years, there is a growing interest in using quantum computers for solving combinatorial optimization problems. In this work, we developed a generic, machine learning-based framework for mapping continuous-space inverse design…

Quantum annealing offers a promising paradigm for solving NP-hard combinatorial optimization problems, but its practical application is severely hindered by two challenges: the complex, manual process of translating problem descriptions…

Machine Learning · Computer Science 2025-09-03 Huixiang Zhang , Mahzabeen Emu , Salimur Choudhury

We present a novel formulation of structural design optimization problems specifically tailored to be solved by quantum annealing (QA). Structural design optimization aims to find the best, i.e., material-efficient yet high-performance,…

Computational Engineering, Finance, and Science · Computer Science 2024-04-17 Fabian Key , Lukas Freinberger

Quadratic unconstrained binary optimization (QUBO) problems are well-studied, not least because they can be approached using contemporary quantum annealing or classical hardware acceleration. However, due to limited precision and hardware…

Quantum Physics · Physics 2023-07-06 Sascha Mücke , Thore Gerlach , Nico Piatkowski

Linear regression is a data analysis technique, which is categorized as supervised learning. By utilizing known data, we can predict unknown data. Recently, researchers have explored the use of quantum annealing (QA) to perform linear…

Quantum Physics · Physics 2024-10-14 Asuka Koura , Takashi Imoto , Katsuki Ura , Yuichiro Matsuzaki

The broad applicability of Quadratic Unconstrained Binary Optimization (QUBO) constitutes a general-purpose modeling framework for combinatorial optimization problems and are a required format for gate array and quantum annealing computers.…

Artificial Intelligence · Computer Science 2021-04-06 Amit Verma , Mark Lewis

Quantum annealing technologies aim to solve computational optimization and sampling problems. QPU (Quantum Processing Unit) machines such as the D-Wave system use the QUBO (Quadratic Unconstrained Binary Optimization) formula to define…

Quantum Physics · Physics 2022-03-28 Toufan D. Tambunan , Andriyan B. Suksmono , Ian J. M. Edward , Rahmat Mulyawan

Recent advances in quantum computing and the increasing availability of quantum hardware have substantially enhanced the practical relevance of quantum approaches to discrete optimization. Among these, the Quadratic Unconstrained Binary…

Quantum Physics · Physics 2026-02-12 Felix P. Broesamle , Stefan Nickel

We address numerical differentiation under coarse, non-uniform sampling and Gaussian noise. A maximum-likelihood estimator with $L_2$-norm constraint on a higher-order derivative is obtained, yielding spline-based solution. We introduce a…

Methodology · Statistics 2025-07-31 Konstantin E. Avrachenkov , Leonid B. Freidovich

Quadratic Unconstrained Binary Optimization (QUBO)-based suppression in object detection is known to have superiority to conventional Non-Maximum Suppression (NMS), especially for crowded scenes where NMS possibly suppresses the…

Computer Vision and Pattern Recognition · Computer Science 2025-02-06 Keiichiro Yamamura , Toru Mitsutake , Hiroki Ishikura , Daiki Kusuhara , Akihiro Yoshida , Katsuki Fujisawa

Ising machines, including quantum annealing machines, are promising next-generation computers for combinatorial optimization problems. However, due to hardware limitations, most Ising-type hardware can only solve objective functions…

Statistical Mechanics · Physics 2025-10-29 Kazuki Ikeuchi , Yoshiki Matsuda , Shu Tanaka

In this paper, we introduce three QUBO (Quadratic Unconstrained Binary Optimization) relaxations for the sparsest $k$-subgraph (SkS) problem: a quadratic penalty relaxation, a Lagrangian relaxation, and an augmented Lagrangian relaxation.…

Optimization and Control · Mathematics 2025-09-11 Omkar Bihani , Roman Kužel , Janez Povh , Dunja Pucher

The Quadratic Unconstrained Binary Optimization (QUBO) modeling and solution framework is a requirement for quantum and digital annealers. However optimality for QUBO problems of any practical size is extremely difficult to achieve. In…

Artificial Intelligence · Computer Science 2021-05-13 Amit Verma , Mark Lewis

So-called sparse estimators arise in the context of model fitting, when one a priori assumes that only a few (unknown) model parameters deviate from zero. Sparsity constraints can be useful when the estimation problem is under-determined,…

Machine Learning · Statistics 2017-03-22 Jean Daunizeau

Quantum Approximate Optimization Algorithm (QAOA) can be used to solve quadratic unconstrained binary optimization (QUBO) problems. However, the size of the solvable problem is limited by the number of qubits. To leverage noisy…

Quantum Physics · Physics 2025-06-10 Wending Zhao , Gaoxiang Tang

The LogQ algorithm encodes Quadratic Unconstrained Binary Optimization (QUBO) problems with exponentially fewer qubits than the Quantum Approximate Optimization Algorithm (QAOA). The advantages of conventional LogQ are accompanied by a…

Quantum Physics · Physics 2025-07-14 Yagnik Chatterjee , Jérémie Messud

Quadratic unconstrained binary optimization (QUBO) is the mathematical formalism for phrasing and solving a class of optimization problems that are combinatorial in nature. Due to their natural equivalence with the two dimensional Ising…

NP problems are closely related to practical optimization challenges but often suffer from exponential increases in computation time as problem sizes grow. Quantum annealing offers a promising approach to solve NP problems faster than…

Quantum Physics · Physics 2025-04-14 Toru Fujii , Koshi Komuro , Kaito Tomari