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Medical imaging plays a vital role in modern diagnostics; however, interpreting high-resolution radiological data remains time-consuming and susceptible to variability among clinicians. Traditional image processing techniques often lack the…

Medical image segmentation has been significantly advanced by deep learning (DL) techniques, though the data scarcity inherent in medical applications poses a great challenge to DL-based segmentation methods. Self-supervised learning offers…

Deep learning (DL) models for segmenting various anatomical structures have achieved great success via a static DL model that is trained in a single source domain. Yet, the static DL model is likely to perform poorly in a continually…

In recent years, deep convolutional neural network-based segmentation methods have achieved state-of-the-art performance for many medical analysis tasks. However, most of these approaches rely on optimizing the U-Net structure or adding new…

We introduce a model-based image reconstruction framework with a convolution neural network (CNN) based regularization prior. The proposed formulation provides a systematic approach for deriving deep architectures for inverse problems with…

Separating and labeling each instance of a nucleus (instance-aware segmentation) is the key challenge in segmenting single cell nuclei on fluorescence microscopy images. Deep Neural Networks can learn the implicit transformation of a…

Background and objective: Employing deep learning models in critical domains such as medical imaging poses challenges associated with the limited availability of training data. We present a strategy for improving the performance and…

Deep learning has been proven to yield reliably generalizable answers to numerous classification and decision tasks. Here, we demonstrate for the first time, to our knowledge, that deep neural networks (DNNs) can be trained to solve inverse…

Convolutional neural networks have been proven effective in a variety of image restoration tasks. Most state-of-the-art solutions, however, are trained using images with a single particular degradation level, and their performance…

Physics-driven deep learning (PD-DL) approaches have become popular for improved reconstruction of fast magnetic resonance imaging (MRI) scans. Though PD-DL offers higher acceleration rates than existing clinical fast MRI techniques, their…

Model-based deep learning (MBDL) is a powerful methodology for designing deep models to solve imaging inverse problems. MBDL networks can be seen as iterative algorithms that estimate the desired image using a physical measurement model and…

Medical imaging is playing a more and more important role in clinics. However, there are several issues in different imaging modalities such as slow imaging speed in MRI, radiation injury in CT and PET. Therefore, accelerating MRI, reducing…

Deep convolutional neural networks (DCNN) have enjoyed great successes in many signal processing applications because they can learn complex, non-linear causal relationships from input to output. In this light, DCNNs are well suited for the…

Machine learning (ML) has seen enormous consideration during the most recent decade. This success started in 2012 when an ML model accomplished a remarkable triumph in the ImageNet Classification, the world's most famous competition for…

Deep learning approaches applied to medical imaging have reached near-human or better-than-human performance on many diagnostic tasks. For instance, the CheXpert competition on detecting pathologies in chest x-rays has shown excellent…

Deep learning (DL) has emerged as a powerful tool for accelerated MRI reconstruction, but often necessitates a database of fully-sampled measurements for training. Recent self-supervised and unsupervised learning approaches enable training…

Deep Learning (DL), in particular deep neural networks (DNN), by default is purely data-driven and in general does not require physics. This is the strength of DL but also one of its key limitations when applied to science and engineering…

This paper tackles a new problem setting: reinforcement learning with pixel-wise rewards (pixelRL) for image processing. After the introduction of the deep Q-network, deep RL has been achieving great success. However, the applications of…

Deep learning has emerged as a powerful artificial intelligence tool to interpret medical images for a growing variety of applications. However, the paucity of medical imaging data with high-quality annotations that is necessary for…

A unified self-supervised and supervised deep learning framework for PET image reconstruction is presented, including deep-learned filtered backprojection (DL-FBP) for sinograms, deep-learned backproject then filter (DL-BPF) for…