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Grouping patients meaningfully can give insights about the different types of patients, their needs, and the priorities. Finding groups that are meaningful is however very challenging as background knowledge is often required to determine…

Databases · Computer Science 2019-04-04 Seyed Amin Tabatabaei , Xixi Lu , Mark Hoogendoorn , Hajo A. Reijers

Process discovery algorithms automatically extract process models from event logs, but high variability often results in complex and hard-to-understand models. To mitigate this issue, trace clustering techniques group process executions…

Machine Learning · Computer Science 2025-12-11 Jari Peeperkorn , Johannes De Smedt , Jochen De Weerdt

Due to the wider availability of modern electronic health records, patient care data is often being stored in the form of time-series. Clustering such time-series data is crucial for patient phenotyping, anticipating patients' prognoses by…

Medical Physics · Physics 2020-06-17 Changhee Lee , Mihaela van der Schaar

Irregularly sampled time series data are common in a variety of fields. Many typical methods for drawing insight from data fail in this case. Here we attempt to generalize methods for clustering trajectories to irregularly and sparsely…

Quantitative Methods · Quantitative Biology 2021-09-01 Gary K. Nave , Swati Padhee , Amanuel Alambo , Tanvi Banerjee , Nirmish Shah , Daniel M. Abrams

Diabetes is one of the most prevalent diseases worldwide, characterized by persistently high blood sugar levels, capable of damaging various internal organs and systems. Diabetes patients require routine check-ups, resulting in a time…

Machine Learning · Computer Science 2025-05-13 Onthada Preedasawakul , Nathakhun Wiroonsri

Within the field of process mining, several different trace clustering approaches exist for partitioning traces or process instances into similar groups. Typically, this partitioning is based on certain patterns or similarity between the…

Machine Learning · Computer Science 2022-08-18 Pieter De Koninck , Klaas Nelissen , Seppe vanden Broucke , Bart Baesens , Monique Snoeck , Jochen De Weerdt

One way of getting a better view of data is using frequent patterns. In this paper frequent patterns are subsets that occur a minimal number of times in a stream of itemsets. However, the discovery of frequent patterns in streams has always…

Artificial Intelligence · Computer Science 2007-05-23 Edgar H. de Graaf , Joost N. Kok , Walter A. Kosters

Improving the future of healthcare starts by better understanding the current actual practices in hospital settings. This motivates the objective of discovering typical care pathways from patient data. Revealing typical care pathways can be…

Machine Learning · Computer Science 2024-12-20 Thomas Guyet , Pierre Pinson , Enoal Gesny

This study develops a pattern recognition method that identifies patterns based on their similarity and their association with the outcome of interest. The practical purpose of developing this pattern recognition method is to group…

Machine Learning · Computer Science 2020-11-20 Hadi Akbarzadeh Khorshidi , Uwe Aickelin , Gholamreza Haffari , Behrooz Hassani-Mahmooei

Recent years have seen an increased focus into the tasks of predicting hospital inpatient risk of deterioration and trajectory evolution due to the availability of electronic patient data. A common approach to these problems involves…

Machine Learning · Computer Science 2020-11-18 Henrique Aguiar , Mauro Santos , Peter Watkinson , Tingting Zhu

The increase in availability of longitudinal electronic health record (EHR) data is leading to improved understanding of diseases and discovery of novel phenotypes. The majority of clustering algorithms focus only on patient trajectories,…

Machine Learning · Computer Science 2021-11-12 Oliver Carr , Avelino Javer , Patrick Rockenschaub , Owen Parsons , Robert Dürichen

In electronic health records (EHRs), clustering patients and distinguishing disease subtypes are key tasks to elucidate pathophysiology and aid clinical decision-making. However, clustering in healthcare informatics is still based on…

Machine Learning · Computer Science 2026-04-09 Manar D. Samad , Yina Hou , Shrabani Ghosh

We introduce a novel profile-based patient clustering model designed for clinical data in healthcare. By utilizing a method grounded on constrained low-rank approximation, our model takes advantage of patients' clinical data and digital…

Machine Learning · Computer Science 2023-08-24 Dongjin Choi , Andy Xiang , Ozgur Ozturk , Deep Shrestha , Barry Drake , Hamid Haidarian , Faizan Javed , Haesun Park

In machine learning and data mining, Cluster analysis is one of the most widely used unsupervised learning technique. Philosophy of this algorithm is to find similar data items and group them together based on any distance function in…

Machine Learning · Statistics 2018-10-09 Kumarjit Pathak , Jitin Kapila

Process discovery aims at automatically creating process models on the basis of event data captured during the execution of business processes. Process discovery algorithms tend to use all of the event data to discover a process model. This…

Databases · Computer Science 2019-12-03 Mohammadreza Fani Sani , Mathilde Boltenhagen , Wil van der Aalst

Predictive marker patterns in imaging data are a means to quantify disease and progression, but their identification is challenging, if the underlying biology is poorly understood. Here, we present a method to identify predictive texture…

Computer Vision and Pattern Recognition · Computer Science 2020-02-11 Matthias Perkonigg , Daniel Sobotka , Ahmed Ba-Ssalamah , Georg Langs

Many diseases display heterogeneity in clinical features and their progression, indicative of the existence of disease subtypes. Extracting patterns of disease variable progression for subtypes has tremendous application in medicine, for…

Quantitative Methods · Quantitative Biology 2020-08-04 Sanjukta Krishnagopal

This review provides a systematic overview of methods that combine covariate-based clustering of observational units (patients) with outcome models for clinical studies. We distinguish between informed-cluster models, where the outcome…

Clustering is a widely used unsupervised learning method for finding structure in the data. However, the resulting clusters are typically presented without any guarantees on their robustness; slightly changing the used data sample or…

Machine Learning · Statistics 2017-01-02 Andreas Henelius , Kai Puolamäki , Henrik Boström , Panagiotis Papapetrou

The identification of phenotypes within complex diseases or syndromes is a fundamental component of precision medicine, which aims to adapt healthcare to individual patient characteristics. Postoperative delirium (POD) is a complex…

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