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We develop three efficient approaches for generating visual explanations from 3D convolutional neural networks (3D-CNNs) for Alzheimer's disease classification. One approach conducts sensitivity analysis on hierarchical 3D image…

Computer Vision and Pattern Recognition · Computer Science 2018-07-09 Chengliang Yang , Anand Rangarajan , Sanjay Ranka

In this work, we introduce a technique of deriving symmetric connectivity matrices from regional histograms of grey-matter volume estimated from T1-weighted MRIs. We then validated the technique by inputting the connectivity matrices into a…

Quantitative Methods · Quantitative Biology 2020-05-28 Matthew Leming , Simon Baron-Cohen , John Suckling

Focal cortical dysplasia (FCD) is a leading cause of drug-resistant focal epilepsy, which can be cured by surgery. These lesions are extremely subtle and often missed even by expert neuroradiologists. "Ground truth" manual lesion masks are…

Image and Video Processing · Electrical Eng. & Systems 2023-06-06 Hannah Spitzer , Mathilde Ripart , Abdulah Fawaz , Logan Z. J. Williams , MELD project , Emma Robinson , Juan Eugenio Iglesias , Sophie Adler , Konrad Wagstyl

Spectral graph convolutional neural networks (GCNNs) have been producing encouraging results in graph classification tasks. However, most spectral GCNNs utilize fixed graphs when aggregating node features, while omitting edge feature…

Computer Vision and Pattern Recognition · Computer Science 2022-10-06 Yang Yi , Xuequan Lu , Shang Gao , Antonio Robles-Kelly , Yuejie Zhang

Resting state functional magnetic resonance images (fMRI) are commonly used for classification of patients as having Alzheimer's disease (AD), mild cognitive impairment (MCI), or being cognitive normal (CN). Most methods use time-series…

Image and Video Processing · Electrical Eng. & Systems 2021-04-22 Nazanin Beheshti , Lennart Johnsson

Attention Deficit Hyperactivity Disorder (ADHD) is a prevalent neurodevelopmental disorder whose neuroimaging-based diagnosis remains challenging due to complex time-varying disruptions in brain connectivity. Functional MRI (fMRI) provides…

Machine Learning · Computer Science 2026-03-30 Qurat Ul Ain , Alptekin Temizel , Soyiba Jawed

Autism spectrum disorder (ASD) is a neurodevelopmental condition impacting high-level cognitive processing and social behavior. Recognizing the distributed nature of brain function, neuroscientists are exploiting the connectome to aid with…

Neurons and Cognition · Quantitative Biology 2019-09-26 Ai Wern Chung , Markus D. Schirmer

Recently, Geometric Deep Learning (GDL) has been introduced as a novel and versatile framework for computer-aided disease classification. GDL uses patient meta-information such as age and gender to model patient cohort relations in a graph…

Machine Learning · Computer Science 2020-05-05 Hendrik Burwinkel , Anees Kazi , Gerome Vivar , Shadi Albarqouni , Guillaume Zahnd , Nassir Navab , Seyed-Ahmad Ahmadi

Dynamic functional connectivity analysis provides valuable information for understanding brain functional activity underlying different cognitive processes. Besides sliding window based approaches, a variety of methods have been developed…

Computer Vision and Pattern Recognition · Computer Science 2018-09-18 Hongming Li , Yong Fan

Graph deep learning models, a class of AI-driven approaches employing a message aggregation mechanism, have gained popularity for analyzing the functional brain connectome in neuroimaging. However, their actual effectiveness remains…

Neural and Evolutionary Computing · Computer Science 2026-02-10 Keqi Han , Yao Su , Lifang He , Liang Zhan , Sergey Plis , Vince Calhoun , Carl Yang

Convolutional neural networks (CNNs) have massively impacted visual recognition in 2D images, and are now ubiquitous in state-of-the-art approaches. CNNs do not easily extend, however, to data that are not represented by regular grids, such…

Computer Vision and Pattern Recognition · Computer Science 2018-03-29 Nitika Verma , Edmond Boyer , Jakob Verbeek

Convolutional Neural Network (CNN) has been successfully applied on classification of both natural images and medical images but not yet been applied to differentiating patients with schizophrenia from healthy controls. Given the subtle,…

Computer Vision and Pattern Recognition · Computer Science 2020-03-20 Mengjiao Hu , Kang Sim , Juan Helen Zhou , Xudong Jiang , Cuntai Guan

To explain individual differences in development, behavior, and cognition, most previous studies focused on projecting resting-state functional MRI (fMRI) based functional connectivity (FC) data into a low-dimensional space via linear…

Neurons and Cognition · Quantitative Biology 2018-11-01 Li Xiao , Julia M. Stephen , Tony W. Wilson , Vince D. Calhoun , Yu-Ping Wang

Finding the biomarkers associated with ASD is helpful for understanding the underlying roots of the disorder and can lead to earlier diagnosis and more targeted treatment. A promising approach to identify biomarkers is using Graph Neural…

Machine Learning · Computer Science 2019-07-15 Xiaoxiao Li , Nicha C. Dvornek , Yuan Zhou , Juntang Zhuang , Pamela Ventola , James S. Duncan

Autism spectrum disorder (ASD) is a complex neurodevelopmental condition characterized by atypical functional brain connectivity and subtle structural alterations. rs-fMRI has been widely used to identify disruptions in large-scale brain…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Ansar Rahman , Hassan Shojaee-Mend , Sepideh Hatamikia

Detection of coronary artery stenosis in coronary CT angiography (CCTA) requires highly personalized surface meshes enclosing the coronary lumen. In this work, we propose to use graph convolutional networks (GCNs) to predict the spatial…

Image and Video Processing · Electrical Eng. & Systems 2019-08-16 Jelmer M. Wolterink , Tim Leiner , Ivana Išgum

In this article, we study association between the structural connectome and cognitive profiles using a multi-response nonparametric regression model.The cognitive profiles are measured in terms of seven age-adjusted cognitive test scores.…

Methodology · Statistics 2022-12-06 Arkaprava Roy

Recent advances in image classification have been significantly propelled by the integration of Graph Convolutional Networks (GCNs), offering a novel paradigm for handling complex data structures. This study introduces an innovative…

Computer Vision and Pattern Recognition · Computer Science 2025-08-21 Mustafa Mohammadi Gharasuie , Luis Rueda

The human brain is highly adaptive: its functional connectivity reconfigures on multiple timescales during cognition and learning, enabling flexible information processing. By contrast, artificial neural networks typically rely on…

Neural and Evolutionary Computing · Computer Science 2025-10-29 Peilin He , Tananun Songdechakraiwut

Deep Neural Networks - especially Convolutional Neural Network (ConvNet) has become the state-of-the-art for image classification, pattern recognition and various computer vision tasks. ConvNet has a huge potential in medical domain for…

Computer Vision and Pattern Recognition · Computer Science 2020-09-11 Md Motiur Rahman Sagar , Martin Dyrba
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