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We present results from Langevin dynamics simulations of a glassy active-passive mixture of soft-repulsive binary colloidal disks. Activity on the smaller particles is applied according to the quorum sensing scheme, in which a smaller…

Soft Condensed Matter · Physics 2020-12-10 Jalim Singh , A. V. Anil Kumar

Concentrated solutions of short blunt-ended DNA duplexes, down to 6 base pairs, are known to order into the nematic liquid crystal phase. This self-assembly is due to the stacking interactions between the duplex terminals that promotes…

Soft Condensed Matter · Physics 2015-05-30 Cristiano De Michele , Tommaso Bellini , Francesco Sciortino

It is known that purely repulsive self-propelled colloids can undergo bulk liquid-vapor phase separation. In experiments and large scale simulations, however, more complex steady states are also seen, comprising a dynamic population of…

Soft Condensed Matter · Physics 2018-10-03 Elsen Tjhung , Cesare Nardini , Michael E. Cates

Phase separation has recently emerged as an important organizational principle in the dense and heterogeneous environment within living cells. Here, we use a synthetic system to show that compressive stresses in a polymer network suppress…

We systematically explore the self-assembly of semi-flexible polymers in deformable spherical confinement across a wide regime of chain stiffness, contour lengths and packing fractions by means of coarse-grained molecular dynamics…

Soft Condensed Matter · Physics 2021-07-12 Maxime M. C. Tortora , Daniel Jost

Multicanonical ensemble sampling simulations have been performed to calculate the phase diagram of a Lennard-Jones fluid embedded in a fractal random matrix generated through diffusion limited cluster aggregation. The study of the system at…

Statistical Mechanics · Physics 2015-06-25 V. De Grandis , P. Gallo , M. Rovere

Spontaneous emergence of organized states in materials driven by non-equilibrium conditions is of significant fundamental and technological interest. In many cases, the organized states are complex, hence, with some well-studied exceptions,…

Soft Condensed Matter · Physics 2021-09-17 Geet Raju , Nikos Kyriakopoulos , Jaakko V. I. Timonen

Multi-component membranes such as ternary mixtures of lipids and cholesterol can exhibit coexistence regions between two liquid phases. When such membranes adhere to a corrugated substrate, the phase separation process strongly depends on…

Soft Condensed Matter · Physics 2009-11-13 Bartosz Rozycki , Thomas R. Weikl , Reinhard Lipowsky

Self-assembly is traditionally described as the process through which an initially disordered system relaxes towards an equilibrium ordered phase only driven by local interactions between its building blocks. However, This definition is too…

Soft Condensed Matter · Physics 2015-06-15 Lorenzo Di Michele , Francesco Varrato , Jurij Kotar , Simon H. Nathan , Giuseppe Foffi , Erika Eiser

Aerobreakup of fluid droplets under the influence of impulsively generated high-speed gas flow using an open-ended shock tube is studied using experiments and numerical simulations. Breakup of mm-sized droplets at high Weber number was…

Fluid Dynamics · Physics 2022-06-24 James Leung , Mohana Gurunadhan , Shyam Menon

Self-bound many-body systems are formed through a balance of attractive and repulsive forces and occur in many physical scenarios. Liquid droplets are an example of a self-bound system, formed by a balance of the mutual attractive and…

Biomolecular condensates such as membraneless organelles, underpinned by liquid-liquid phase separation (LLPS), are important for physiological function, with electrostatics -- among other interaction types -- being a prominent force in…

Biomolecules · Quantitative Biology 2021-05-26 Jonas Wessén , Tanmoy Pal , Suman Das , Yi-Hsuan Lin , Hue Sun Chan

The onset of polar flocking in active matter is discontinuous, akin to gas-liquid phase transitions, except that the steady state exhibits microphase separation into polar clusters. While these features have been observed in theoretical…

Soft Condensed Matter · Physics 2021-03-31 Lorenz Huber , Timo Krüger , Erwin Frey

We analyze large systems of interacting proteins, using techniques from the non-equilibrium statistical mechanics of disordered many-particle systems. Apart from protein production and removal, the most relevant microscopic processes in the…

Molecular Networks · Quantitative Biology 2015-05-14 A. C. C. Coolen , S. Rabello

We investigate by time-resolved Synchrotron ultra-small X-ray scattering the dynamics of liquid-liquid phase-separation (LLPS) of gluten protein suspensions following a temperature quench. Samples at a fixed concentration (237 mg/ml) but…

Soft Condensed Matter · Physics 2019-08-27 A. Banc , J. Pincemaille , S. Costanzo , E. Chauveau , M. s. Appavou , M. H. Morel , P. Menut , L. Ramos

We consider a microscopic model of a polymer blend that is prone to phase separation. Permanent crosslinks are introduced between randomly chosen pairs of monomers, drawn from the Deam-Edwards distribution. Thereby, not only density but…

Soft Condensed Matter · Physics 2009-11-11 Christian Wald , Paul M. Goldbart , Annette Zippelius

Crystallization of biological molecules has high potential to solve some challenges in drug manufacturing. Thus, understanding the process is critical to efficiently adapting crystallization to biopharmaceutical manufacturing. This article…

Phase separation and transitions among different molecular states are ubiquitous in living cells. Such transitions can be governed by local equilibrium thermodynamics or by active processes controlled by biological fuel. It remains largely…

Biological Physics · Physics 2021-11-24 G. Bartolucci , O. Adame-Arana , X. Zhao , C. A. Weber

Microphase separation is common in active biological systems as exemplified by the separation of RNA and DNA-rich phases in the cell nucleus driven by the transcriptional activity of polymerase enzymes acting similarly to amphiphiles in a…

Soft Condensed Matter · Physics 2025-07-22 Rakesh Chatterjee , Hui-Shun Kuan , Frank Julicher , Vasily Zaburdaev

Spontaneous self-assembly in molecular systems is a fundamental route to both biological and engineered soft matter. Simple micellisation, emulsion formation, and polymer mixing principles are well understood. However, the principles behind…

Soft Condensed Matter · Physics 2021-09-21 Alberto Scacchi , Sousa Javan Nikkhah , Maria Sammalkorpi , Tapio Ala-Nissila