Related papers: Multispectral Photon-Counting for Medical Imaging …
Photon number resolving (PNR) measurements are beneficial or even necessary for many applications in quantum optics. Unfortunately, PNR detectors are usually large, slow, expensive, and difficult to operate. However, if the input signal is…
Treatment planning systems at proton-therapy centres generally use X-ray computed tomography (CT) as primary imaging technique to infer the proton treatment doses to tumour and healthy tissues. However, proton stopping powers in the body,…
MCP-based detectors are widely used in the ultraviolet (UV) region due to their low noise levels, high sensitivity and good spatial and temporal resolution. We have developed a compact near-UV (NUV) detector for high-altitude balloon and…
Two detectors for energy-resolved fast-neutron imaging in pulsed broad-energy neutron beams are presented. The first one is a neutron-counting detector based on a solid neutron converter coupled to a gaseous electron multiplier (GEM). The…
Ghost imaging is demonstrated using a poly-energetic reactor source of thermal neutrons. The method presented enables position resolution to be incorporated, into a variety of neutron instruments that are not position resolving. In an…
Charged particle therapy (CPT) is an advanced modality of radiation therapy which has grown rapidly worldwide, driven by recent developments in technology and methods of delivery. To ensure safe and high quality treatments, various…
Photon-counting computed tomography (PCCT) marks a significant advancement over conventional energy-integrating detector (EID) CT systems. This review highlights PCCT's superior spatial and contrast resolution, reduced radiation dose, and…
Boron Neutron Capture Therapy (BNCT) is a neutron radiotherapy used to treat tumours cells previously doping with Boron-10. This therapy requires an epithermal neutron beam for the treatment of deep tumours and a thermal beam for shallow…
Fast neutron detection is often based on the neutron-proton elastic scattering reaction: the ionization caused by recoil protons in a hydrogenous material constitutes the basic information for the design and development of a class of…
High-resolution x-ray tomography is a common technique for biomedical research using synchrotron sources. With advancements in laboratory x-ray sources, an increasing number of experiments can be performed in the lab. In this paper, the…
Bremsstrahlung photon beams produced by medical linear accelerators are currently the most commonly used method of radiation therapy for cancerous tumors. Photons with energies greater than 8-10 MeV potentially generate neutrons through…
In the last decade, several photon counting technologies have been developed opening a new window for experiments in the low photon number regime. Several ongoing and future projects in HEP benefit from these developments, which will also…
Determining an unknown quantum state from an ensemble of identical systems is a fundamental, yet experimentally demanding, task in quantum science. Here we study the number of measurement bases needed to fully characterize an arbitrary…
Beam monitoring and evaluation are very important to boron neutron capture therapy (BNCT), and a variety of detectors have been developed for these applications. However, most of the detectors used in BNCT only have a small detection area,…
The major advantage of proton therapy over conventional radiotherapy is the dose deposition pattern, enabling precise coverage of the tumour volume while sparing nearby healthy tissues. However, accurate control of the proton beam range…
We report a comprehensive approach to analysing continuous-output photon detectors. We employ principal component analysis to maximise the information extracted, followed by a novel noise-tolerant parameterised approach to the tomography of…
We develop a novel algorithm for characterizing Deep Sub-Electron Read Noise (DSERN) image sensors. This algorithm is able to simultaneously compute maximum likelihood estimates of quanta exposure, conversion gain, bias, and read noise of…
Objective. Prompt-gamma imaging encompasses several approaches for online monitoring of beam range or deposited dose distribution in proton therapy. We test one of the imaging techniques - a coded mask approach - both experimentally and via…
Fundamental understanding of biological pathways requires minimally invasive nanoscopic optical resolution imaging. Many approaches to high-resolution imaging rely on localization of single emitters, such as fluorescent molecule or quantum…
We present the experimental demonstration of a superconducting photon number resolving detector. It is based on the series connection of N superconducting nanowires, each connected in parallel to an integrated resistor. The device provides…