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The trade-off between predictive accuracy and data availability makes it difficult to predict protein--protein binding affinity accurately. The lack of experimentally resolved protein structures limits the performance of structure-based…

Machine Learning · Computer Science 2026-01-08 Wajid Arshad Abbasi , Syed Ali Abbas , Maryum Bibi , Saiqa Andleeb , Muhammad Naveed Akhtar

Protein-Protein Interaction Networks aim to model the interactome, providing a powerful tool for understanding the complex relationships governing cellular processes. These networks have numerous applications, including functional…

Molecular Networks · Quantitative Biology 2023-10-05 Rodrigo Henrique Ramos , Cynthia de Oliveira Lage Ferreira , Adenilso Simao

Advancements in adapting deep convolution architectures for Spiking Neural Networks (SNNs) have significantly enhanced image classification performance and reduced computational burdens. However, the inability of Multiplication-Free…

Neural and Evolutionary Computing · Computer Science 2024-04-29 Boyan Li , Luziwei Leng , Shuaijie Shen , Kaixuan Zhang , Jianguo Zhang , Jianxing Liao , Ran Cheng

Recent advancements in deep neural networks have shown promise in aiding disease diagnosis and medical decision-making. However, ensuring transparent decision-making processes of AI models in compliance with regulations requires a…

Computer Vision and Pattern Recognition · Computer Science 2024-07-17 Hyeon Bae Kim , Yong Hyun Ahn , Seong Tae Kim

Protein representation learning methods have shown great potential to yield useful representation for many downstream tasks, especially on protein classification. Moreover, a few recent studies have shown great promise in addressing…

Machine Learning · Computer Science 2023-04-11 Can Chen , Jingbo Zhou , Fan Wang , Xue Liu , Dejing Dou

As the use of interactive machines grow, the task of Emotion Recognition in Conversation (ERC) became more important. If the machine-generated sentences reflect emotion, more human-like sympathetic conversations are possible. Since emotion…

Computation and Language · Computer Science 2022-04-22 Joosung Lee , Wooin Lee

During the last years, there has been a lot of interest in achieving some kind of complex reasoning using deep neural networks. To do that, models like Memory Networks (MemNNs) have combined external memory storages and attention…

Computation and Language · Computer Science 2018-05-25 Juan Pavez , Héctor Allende , Héctor Allende-Cid

Gene/protein interactions provide critical information for a thorough understanding of cellular processes. Recently, considerable interest and effort has been focused on the construction and analysis of genome-wide gene networks. The large…

Molecular Networks · Quantitative Biology 2022-04-25 Xin Li , Hsinchun Chen , Zan Huang , Hua Su , Jesse D. Martinez

Recently, end-to-end memory networks have shown promising results on Question Answering task, which encode the past facts into an explicit memory and perform reasoning ability by making multiple computational steps on the memory. However,…

Information Retrieval · Computer Science 2016-09-29 Jiaming Xu , Jing Shi , Yiqun Yao , Suncong Zheng , Bo Xu , Bo Xu

Protein interaction networks (PINs) are often used to "learn" new biological function from their topology. Since current PINs are noisy, their computational de-noising via link prediction (LP) could improve the learning accuracy. LP uses…

Molecular Networks · Quantitative Biology 2013-07-15 Ryan W. Solava , Tijana Milenković

The goal of protein representation learning is to extract knowledge from protein databases that can be applied to various protein-related downstream tasks. Although protein sequence, structure, and function are the three key modalities for…

Biomolecules · Quantitative Biology 2024-05-14 Eunji Ko , Seul Lee , Minseon Kim , Dongki Kim

The evolution processes of complex systems carry key information in the systems' functional properties. Applying machine learning algorithms, we demonstrate that the historical formation process of various networked complex systems can be…

Physics and Society · Physics 2024-03-25 Junya Wang , Yi-Jiao Zhang , Cong Xu , Jiaze Li , Jiachen Sun , Jiarong Xie , Ling Feng , Tianshou Zhou , Yanqing Hu

Successive whole genome duplications have recently been firmly established in all major eukaryote kingdoms. It is not clear, however, how such dramatic evolutionary process has contributed to shape the large scale topology of…

Molecular Networks · Quantitative Biology 2007-05-23 K. Evlampiev , H. Isambert

Conventional predictive modeling of parametric relationships in manufacturing processes is limited by the subjectivity of human expertise and intuition on the one hand and by the cost and time of experimental data generation on the other…

Computation and Language · Computer Science 2025-06-26 Kiarash Naghavi Khanghah , Anandkumar Patel , Rajiv Malhotra , Hongyi Xu

We present Pre-trained Machine Reader (PMR), a novel method for retrofitting pre-trained masked language models (MLMs) to pre-trained machine reading comprehension (MRC) models without acquiring labeled data. PMR can resolve the discrepancy…

Computation and Language · Computer Science 2023-10-17 Weiwen Xu , Xin Li , Wenxuan Zhang , Meng Zhou , Wai Lam , Luo Si , Lidong Bing

Pre-trained language models (PLMs) were considered to be able to store relational knowledge present in the training data. However, some relational knowledge seems to be discarded unsafely in PLMs due to \textbf{report bias}: low-frequency…

Computation and Language · Computer Science 2023-05-25 Hongbo Zhang , Xiang Wan , Benyou Wang

Understanding the spatial architecture of the tumor microenvironment (TME) is critical to advance precision oncology. We present ProteinPNet, a novel framework based on prototypical part networks that discovers TME motifs from spatial…

Machine Learning · Computer Science 2025-12-03 Louis McConnell , Jieran Sun , Theo Maffei , Raphael Gottardo , Marianna Rapsomaniki

Image manipulation with natural language, which aims to manipulate images with the guidance of language descriptions, has been a challenging problem in the fields of computer vision and natural language processing (NLP). Currently, a number…

Computer Vision and Pattern Recognition · Computer Science 2021-07-28 Xiangxi Shi , Zhonghua Wu , Guosheng Lin , Jianfei Cai , Shafiq Joty

Micro-expression recognition (MER), a critical subfield of affective computing, presents greater challenges than macro-expression recognition due to its brief duration and low intensity. While incorporating prior knowledge has been shown to…

Computer Vision and Pattern Recognition · Computer Science 2025-06-12 Chuang Ma , Shaokai Zhao , Dongdong Zhou , Yu Pei , Zhiguo Luo , Liang Xie , Ye Yan , Erwei Yin

The field of artificial intelligence faces significant challenges in achieving both biological plausibility and computational efficiency, particularly in visual learning tasks. Current artificial neural networks, such as convolutional…

Machine Learning · Computer Science 2024-09-27 Jacobo Ruiz , Manas Gupta