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Prediction of toxicity levels of chemical compounds is an important issue in Quantitative Structure-Activity Relationship (QSAR) modeling. Although toxicity prediction has achieved significant progress in recent times through deep learning,…

Machine Learning · Computer Science 2019-07-22 Abdul Karim , Jaspreet Singh , Avinash Mishra , Abdollah Dehzangi , M. A. Hakim Newton , Abdul Sattar

Gaussian process regression machine learning with a physically-informed kernel is used to model the phase compositions of nickel-base superalloys. The model delivers good predictions for laboratory and commercial superalloys, with $R^2>0.8$…

Materials Science · Physics 2021-09-29 Patrick L. Taylor , Gareth Conduit

Additive models play an important role in semiparametric statistics. This paper gives learning rates for regularized kernel based methods for additive models. These learning rates compare favourably in particular in high dimensions to…

Machine Learning · Statistics 2014-05-15 Andreas Christmann , Ding-Xuan Zhou

We explore recurrent encoder multi-decoder neural network architectures for semi-supervised sequence classification and reconstruction. We find that the use of multiple reconstruction modules helps models generalize in a classification task…

Computer Vision and Pattern Recognition · Computer Science 2018-07-12 Félix G. Harvey , Julien Roy , David Kanaa , Christopher Pal

Virtual screening can accelerate drug discovery by identifying promising candidates for experimental evaluation. Machine learning is a powerful method for screening, as it can learn complex structure-property relationships from experimental…

Machine Learning · Computer Science 2021-02-22 Simon Axelrod , Rafael Gomez-Bombarelli

Reliable molecular property prediction is essential for various scientific endeavors and industrial applications, such as drug discovery. However, the data scarcity, combined with the highly non-linear causal relationships between…

Machine Learning · Computer Science 2025-01-14 Yue Wan , Jialu Wu , Tingjun Hou , Chang-Yu Hsieh , Xiaowei Jia

The meeting of artificial intelligence (AI) and quantum computing is already a reality; quantum machine learning (QML) promises the design of better regression models. In this work, we extend our previous studies of materials discovery…

Semi-supervised learning is an important and active topic of research in pattern recognition. For classification using linear discriminant analysis specifically, several semi-supervised variants have been proposed. Using any one of these…

Machine Learning · Statistics 2014-11-18 Jesse H. Krijthe , Marco Loog

Image-based profiling techniques have become increasingly popular over the past decade for their applications in target identification, mechanism-of-action inference, and assay development. These techniques have generated large datasets of…

Biomolecules · Quantitative Biology 2023-06-28 Cuong Q. Nguyen , Dante Pertusi , Kim M. Branson

We describe a novel end-to-end approach using Machine Learning to reconstruct the power spectrum of cosmological density perturbations at high redshift from observed quasar spectra. State-of-the-art cosmological simulations of structure…

Cosmology and Nongalactic Astrophysics · Physics 2021-07-21 Maria Han Veiga , Xi Meng , Oleg Y. Gnedin , Nickolay Y. Gnedin , Xun Huan

We present a general framework of semi-supervised dimensionality reduction for manifold learning which naturally generalizes existing supervised and unsupervised learning frameworks which apply the spectral decomposition. Algorithms derived…

Machine Learning · Computer Science 2009-07-29 Ratthachat Chatpatanasiri , Boonserm Kijsirikul

We consider the problem of metric learning subject to a set of constraints on relative-distance comparisons between the data items. Such constraints are meant to reflect side-information that is not expressed directly in the feature vectors…

Machine Learning · Computer Science 2016-12-06 Ehsan Amid , Aristides Gionis , Antti Ukkonen

This article provides an original understanding of the behavior of a class of graph-oriented semi-supervised learning algorithms in the limit of large and numerous data. It is demonstrated that the intuition at the root of these methods…

Machine Learning · Computer Science 2017-11-10 Xiaoyi Mai , Romain Couillet

Machine learning and deep learning have shown great promise in mobile sensing applications, including Human Activity Recognition. However, the performance of such models in real-world settings largely depends on the availability of large…

Machine Learning · Computer Science 2021-02-12 Chi Ian Tang , Ignacio Perez-Pozuelo , Dimitris Spathis , Soren Brage , Nick Wareham , Cecilia Mascolo

Methods for neural network hyperparameter optimization and meta-modeling are computationally expensive due to the need to train a large number of model configurations. In this paper, we show that standard frequentist regression models can…

Machine Learning · Computer Science 2017-11-09 Bowen Baker , Otkrist Gupta , Ramesh Raskar , Nikhil Naik

Quantum Machine Learning (QML) aims to leverage the principles of quantum mechanics to speed up the process of solving machine learning problems or improve the quality of solutions. Among these principles, entanglement with an auxiliary…

Quantum Physics · Physics 2025-09-15 Alexander Mandl , Johanna Barzen , Marvin Bechtold , Frank Leymann , Lavinia Stiliadou

Semi-Supervised Learning (SSL) has shown tremendous potential to improve the predictive performance of deep learning models when annotations are hard to obtain. However, the application of SSL has so far been mainly studied in the context…

Computer Vision and Pattern Recognition · Computer Science 2025-07-30 Ankit Singh , Efstratios Gavves , Cees G. M. Snoek , Hilde Kuehne

Q-learning facilitates the development of an optimal adaptive treatment strategy through stagewise regression on a pre-specified set of tailoring variables and confounders. Semiparametric robust Q-learning eliminates the residual…

We propose a few-shot learning method for spatial regression. Although Gaussian processes (GPs) have been successfully used for spatial regression, they require many observations in the target task to achieve a high predictive performance.…

Machine Learning · Statistics 2020-10-12 Tomoharu Iwata , Yusuke Tanaka

Artificial intelligence (AI) has been widely applied in drug discovery with a major task as molecular property prediction. Despite booming techniques in molecular representation learning, key elements underlying molecular property…

Quantitative Methods · Quantitative Biology 2023-09-06 Jianyuan Deng , Zhibo Yang , Hehe Wang , Iwao Ojima , Dimitris Samaras , Fusheng Wang
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