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The performance of the emerging petaflops-scale supercomputers of the nearest future (hypercomputers) will be governed not only by the clock frequency of the processing nodes or by the width of the system bus, but also by such factors as…

Performance · Computer Science 2011-11-21 Dmitry Zinoviev

This paper presents a systematic review of mapping and scheduling strategies within the High-Performance Computing (HPC) compute continuum, with a particular emphasis on heterogeneous systems. It introduces a prototype workflow to establish…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-05-19 Aasish Kumar Sharma , Julian Kunkel

Cybersecurity has emerged as a critical challenge for the industry. With the large complexity of the security landscape, sophisticated and costly deep learning models often fail to provide timely detection of cyber threats on edge devices.…

Cryptography and Security · Computer Science 2023-04-17 Junyao Wang , Hanning Chen , Mariam Issa , Sitao Huang , Mohsen Imani

With the increasing sophistication and capability of quantum hardware, its integration, and employment in high performance computing (HPC) infrastructure becomes relevant. This opens largely unexplored access models and scheduling questions…

Over the past two decades, the field of high-dimensional statistics has experienced substantial progress, driven largely by technological advances that have dramatically reduced the cost and effort for data collection and storage across a…

The advent of High Performance Computing (HPC) has provided the computational capacity required for power system operators (SO) to obtain solutions in the least time to highly-complex applications, i.e., Unit Commitment (UC). The UC…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-02-14 Mushfiqur R. Sarker , Jianhui Wang

Although high-performance computing (HPC) systems have been scaled to meet the exponentially-growing demand for scientific computing, HPC performance variability remains a major challenge and has become a critical research topic in computer…

Applications · Statistics 2022-05-23 Li Xu , Yili Hong , Max D. Morris , Kirk W. Cameron

This paper addresses the clustering of data in the hyperdimensional computing (HDC) domain. In prior work, an HDC-based clustering framework, referred to as HDCluster, has been proposed. However, the performance of the existing HDCluster is…

Machine Learning · Computer Science 2024-04-19 Lulu Ge , Keshab K. Parhi

Publicly available collections of drug-like molecules have grown to comprise 10s of billions of possibilities in recent history due to advances in chemical synthesis. Traditional methods for identifying "hit" molecules from a large…

Computer-based scientific experiments are becoming increasingly data-intensive, necessitating the use of High-Performance Computing (HPC) clusters to handle large scientific workflows. These workflows result in complex data and control…

Databases · Computer Science 2025-02-17 Zahra Sadeghibogar , Alessandro Berti , Marco Pegoraro , Wil M. P. van der Aalst

Exascale computing will get mankind closer to solving important social, scientific and engineering problems. Due to high prototyping costs, High Performance Computing (HPC) system architects make use of simulation models for design space…

Performance · Computer Science 2018-03-28 Alexandra Ferreron , Radhika Jagtap , Sascha Bischoff , Roxana Rusitoru

This paper presents SHARP (Supercomputing for High-speed Avoidance and Reactive Planning), a proof-of-concept study demonstrating how high-performance computing (HPC) can enable millisecond-scale responsiveness in robotic control. While…

Survival analysis is an important research topic with applications in healthcare, business, and manufacturing. One essential tool in this area is the Cox proportional hazards (CPH) model, which is widely used for its interpretability,…

Machine Learning · Computer Science 2024-10-28 Jiachang Liu , Rui Zhang , Cynthia Rudin

Modern scientific instruments generate data at rates that increasingly exceed local compute capabilities and, when paired with the staging and I/O overheads of file-based transfers, also render file-based use of remote HPC resources…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-10-01 Flavio Castro , Weijian Zheng , Joaquin Chung , Ian Foster , Rajkumar Kettimuthu

In recent years, language models (LMs), such as GPT-4, have been widely used in multiple domains, including natural language processing, visualization, and so on. However, applying them for analyzing and optimizing high-performance…

Machine Learning · Computer Science 2023-11-28 Le Chen , Pei-Hung Lin , Tristan Vanderbruggen , Chunhua Liao , Murali Emani , Bronis de Supinski

This paper is concerned with estimating the column subspace of a low-rank matrix $\boldsymbol{X}^\star \in \mathbb{R}^{n_1\times n_2}$ from contaminated data. How to obtain optimal statistical accuracy while accommodating the widest range…

Statistics Theory · Mathematics 2025-03-18 Yuchen Zhou , Yuxin Chen

Because most technology and computer architecture innovations were (intentionally) invisible to higher layers, application and other software developers could reap the benefits of this progress without engaging in it. Higher performance has…

High-performance computing (HPC) is reshaping computational drug discovery by enabling large-scale, time-efficient molecular simulations. In this work, we explore HPC-driven pipelines for Alzheimer's disease drug discovery, focusing on…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-09-03 Paul Ruiz Alliata , Diana Rubaga , Daniel Kumlin , Alberto Puliga

With the growing complexity of computational and experimental facilities, many scientific researchers are turning to machine learning (ML) techniques to analyze large scale ensemble data. With complexities such as multi-component workflows,…

High Performance Computing (HPC) supercomputers are expected to play an increasingly important role in HEP computing in the coming years. While HPC resources are not necessarily the optimal fit for HEP workflows, computing time at HPC…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-11-20 Federico Stagni , Andrea Valassi , Vladimir Romanovskiy