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As current computing capabilities increase, modern machine learning and computer vision system tend to increase in complexity, mostly by means of larger models and advanced optimization strategies. Although often neglected, in many problems…
Retinoblastoma is the most prominent childhood primary intraocular malignancy that impacts the vision of children and adults worldwide. In contrasting and comparing with adults it is uveal melanoma. It is an aggressive tumor that can fill…
Glaucoma is a disease in which the optic nerve is chronically damaged by the elevation of the intra-ocular pressure, resulting in visual field defect. Therefore, it is important to monitor and treat suspected patients before they are…
A major cause of irreversible visual impairment is angle-closure glaucoma, which can be screened through imagery from Anterior Segment Optical Coherence Tomography (AS-OCT). Previous computational diagnostic techniques address this…
Purpose: (1) To develop a deep learning algorithm to automatically segment structures of the optic nerve head (ONH) and macula in 3D wide-field optical coherence tomography (OCT) scans; (2) To assess whether 3D macula or ONH structures (or…
Accurate detection and segmentation of glomeruli in kidney tissue are essential for diagnostic applications. Traditional deep learning methods primarily rely on semantic segmentation, which often fails to precisely delineate adjacent…
Widespread outreach programs using remote retinal imaging have proven to decrease the risk from diabetic retinopathy, the leading cause of blindness in the US. However, this process still requires manual verification of image quality and…
Ocular diseases, including diabetic retinopathy and glaucoma, present a significant public health challenge due to their high prevalence and potential for causing vision impairment. Early and accurate diagnosis is crucial for effective…
Purpose: To evaluate nerve fiber layer (NFL) reflectance for glaucoma diagnosis using a large dataset. Methods: Participants were imaged with 4.9mm ONH scans using spectral-domain optical coherence tomography (OCT). The NFL reflectance map…
Retinal fundus images are widely used for the clinical screening and diagnosis of eye diseases. However, fundus images captured by operators with various levels of experience have a large variation in quality. Low-quality fundus images…
Retinal vessel segmentation is a vital early detection method for several severe ocular diseases. Despite significant progress in retinal vessel segmentation with the advancement of Neural Networks, there are still challenges to overcome.…
Fundus photography is the primary method for retinal imaging and essential for diabetic retinopathy prevention. Automated segmentation of fundus photographs would improve the quality, capacity, and cost-effectiveness of eye care screening…
The cup-to-disc ratio (CDR) is one of the most significant indicator for glaucoma diagnosis. Different from the use of costly fully supervised learning formulation with pixel-wise annotations in the literature, this study investigates the…
Type 2 Diabetes (T2D) is a chronic metabolic disorder that can lead to blindness and cardiovascular disease. Information about early stage T2D might be present in retinal fundus images, but to what extent these images can be used for a…
Age related macular degeneration (AMD) is one of the major causes for blindness in the elderly population. In this report, we propose deep learning based methods for retinal analysis using color fundus images for computer aided diagnosis of…
Segmentation of retinal vessels from retinal fundus images is the key step in the automatic retinal image analysis. In this paper, we propose a new unsupervised automatic method to segment the retinal vessels from retinal fundus images.…
Parkinson's disease is the world's fastest-growing neurological disorder. Research to elucidate the mechanisms of Parkinson's disease and automate diagnostics would greatly improve the treatment of patients with Parkinson's disease. Current…
Glaucoma is one of the leading causes of blindness worldwide and Optical Coherence Tomography (OCT) is the quintessential imaging technique for its detection. Unlike most of the state-of-the-art studies focused on glaucoma detection, in…
The prevalence of ocular illnesses is growing globally, presenting a substantial public health challenge. Early detection and timely intervention are crucial for averting visual impairment and enhancing patient prognosis. This research…
A glioma is a malignant brain tumor that seriously affects cognitive functions and lowers patients' life quality. Segmentation of brain glioma is challenging because of interclass ambiguities in tumor regions. Recently, deep learning…