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Researchers have proposed that deep learning, which is providing important progress in a wide range of high complexity tasks, might inspire new insights into learning in the brain. However, the methods used for deep learning by artificial…

Neural and Evolutionary Computing · Computer Science 2019-07-03 Isabella Pozzi , Sander Bohté , Pieter Roelfsema

Inspired by biophysical principles underlying nonlinear dendritic computation in neural circuits, we develop a scheme to train deep neural networks to make them robust to adversarial attacks. Our scheme generates highly nonlinear, saturated…

Machine Learning · Statistics 2017-03-28 Aran Nayebi , Surya Ganguli

Our brain consists of biological neurons encoding information through accurate spike timing, yet both the architecture and learning rules of our brain remain largely unknown. Comparing to the recent development of backpropagation-based…

Neural and Evolutionary Computing · Computer Science 2021-11-29 Yukun Yang , Peng Li

We introduce a general theoretical framework, designed for the study of gradient optimisation of deep neural networks, that encompasses ubiquitous architecture choices including batch normalisation, weight normalisation and skip…

Machine Learning · Computer Science 2023-12-05 Lachlan Ewen MacDonald , Jack Valmadre , Hemanth Saratchandran , Simon Lucey

The fields of artificial intelligence and neuroscience have a long history of fertile bi-directional interactions. On the one hand, important inspiration for the development of artificial intelligence systems has come from the study of…

Neurons and Cognition · Quantitative Biology 2019-11-21 Eilif B. Muller , Philippe Beaudoin

The development of biologically-plausible learning algorithms is important for understanding learning in the brain, but most of them fail to scale-up to real-world tasks, limiting their potential as explanations for learning by real brains.…

Neural and Evolutionary Computing · Computer Science 2022-02-01 Maxence Ernoult , Fabrice Normandin , Abhinav Moudgil , Sean Spinney , Eugene Belilovsky , Irina Rish , Blake Richards , Yoshua Bengio

Hebbian plasticity is a powerful principle that allows biological brains to learn from their lifetime experience. By contrast, artificial neural networks trained with backpropagation generally have fixed connection weights that do not…

Neural and Evolutionary Computing · Computer Science 2016-10-20 Thomas Miconi

Understanding how the brain learns may be informed by studying biologically plausible learning rules. These rules, often approximating gradient descent learning to respect biological constraints such as locality, must meet two critical…

Neural and Evolutionary Computing · Computer Science 2025-06-10 Yuhan Helena Liu , Guangyu Robert Yang , Christopher J. Cueva

Backpropagation is the foundational algorithm for training neural networks and a key driver of deep learning's success. However, its biological plausibility has been challenged due to three primary limitations: weight symmetry, reliance on…

Neural and Evolutionary Computing · Computer Science 2025-06-05 Changze Lv , Jingwen Xu , Yiyang Lu , Xiaohua Wang , Zhenghua Wang , Zhibo Xu , Di Yu , Xin Du , Xiaoqing Zheng , Xuanjing Huang

Augmenting neural networks with skip connections, as introduced in the so-called ResNet architecture, surprised the community by enabling the training of networks of more than 1,000 layers with significant performance gains. This paper…

Computer Vision and Pattern Recognition · Computer Science 2020-04-24 Alireza Zaeemzadeh , Nazanin Rahnavard , Mubarak Shah

Significant success has been reported recently using deep neural networks for classification. Such large networks can be computationally intensive, even after training is over. Implementing these trained networks in hardware chips with a…

Machine Learning · Statistics 2013-10-25 Daniel Soudry , Ron Meir

Skip connections are increasingly utilized by deep neural networks to improve accuracy and cost-efficiency. In particular, the recent DenseNet is efficient in computation and parameters, and achieves state-of-the-art predictions by directly…

Computer Vision and Pattern Recognition · Computer Science 2017-11-02 Hanzhang Hu , Debadeepta Dey , Allison Del Giorno , Martial Hebert , J. Andrew Bagnell

Biological evidence suggests that adaptation of synaptic delays on short to medium timescales plays an important role in learning in the brain. Inspired by biology, we explore the feasibility and power of using synaptic delays to solve…

Neural and Evolutionary Computing · Computer Science 2023-08-31 Edoardo W. Grappolini , Anand Subramoney

Artificial neural networks are most commonly trained with the back-propagation algorithm, where the gradient for learning is provided by back-propagating the error, layer by layer, from the output layer to the hidden layers. A recently…

Machine Learning · Statistics 2016-12-22 Arild Nøkland

The ability to learn continuously from an incoming data stream without catastrophic forgetting is critical to designing intelligent systems. Many approaches to continual learning rely on stochastic gradient descent and its variants that…

Machine Learning · Computer Science 2023-08-10 Sandeep Madireddy , Angel Yanguas-Gil , Prasanna Balaprakash

Over past few years afterward the birth of ResNet, skip connection has become the defacto standard for the design of modern architectures due to its widespread adoption, easy optimization and proven performance. Prior work has explained the…

Machine Learning · Computer Science 2023-03-03 Dengsheng Chen , Jie Hu , Wenwen Qiang , Xiaoming Wei , Enhua Wu

The backpropagation algorithm remains the dominant and most successful method for training deep neural networks (DNNs). At the same time, training DNNs at scale comes at a significant computational cost and therefore a high carbon…

Machine Learning · Computer Science 2025-11-12 Sander Dalm , Joshua Offergeld , Nasir Ahmad , Marcel van Gerven

Empowered by the backpropagation (BP) algorithm, deep neural networks have dominated the race in solving various cognitive tasks. The restricted training pattern in the standard BP requires end-to-end error propagation, causing large memory…

Machine Learning · Computer Science 2022-05-17 Wenzhe Guo , Mohammed E Fouda , Ahmed M. Eltawil , Khaled N. Salama

Backpropagation is the default algorithm for training deep neural networks due to its simplicity, efficiency and high convergence rate. However, its requirements make it impossible to be implemented in a human brain. In recent years, more…

Machine Learning · Computer Science 2021-09-01 Albert Jiménez Sanfiz , Mohamed Akrout

Despite extensive theoretical work on biologically plausible learning rules, clear evidence about whether and how such rules are implemented in the brain has been difficult to obtain. We consider biologically plausible supervised- and…

Neural and Evolutionary Computing · Computer Science 2022-10-18 Jacob P. Portes , Christian Schmid , James M. Murray