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Machine-learning-assisted cancer subtyping is a promising avenue in digital pathology. Cancer subtyping models, however, require careful training using expert annotations so that they can be inferred with a degree of known certainty (or…

The problem of selecting a handful of truly relevant variables in supervised machine learning algorithms is a challenging problem in terms of untestable assumptions that must hold and unavailability of theoretical assurances that selection…

Methodology · Statistics 2023-11-10 Mehdi Rostami , Olli Saarela

It is not clear how to target patients who are most likely to benefit from digital care management programs ex-ante, a shortcoming of current risk score based approaches. This study focuses on defining impactability by identifying those…

Quantitative Methods · Quantitative Biology 2019-05-16 Heather Mattie , Patrick Reidy , Patrik Bachtiger , Emily Lindemer , Mohammad Jouni , Trishan Panch

The detection of cardiovascular diseases (CVD) using machine learning techniques represents a significant advancement in medical diagnostics, aiming to enhance early detection, accuracy, and efficiency. This study explores a comparative…

Machine Learning · Computer Science 2024-05-28 Dayana K , S. Nandini , Sanjjushri Varshini R

Gastrointestinal diseases pose significant healthcare chall-enges as they manifest in diverse ways and can lead to potential complications. Ensuring precise and timely classification of these diseases is pivotal in guiding treatment choices…

Computer Vision and Pattern Recognition · Computer Science 2023-07-18 Dibya Nath , G. M. Shahariar

In this study, we investigated the application of bio-inspired optimization algorithms, including Genetic Algorithm, Particle Swarm Optimization, and Whale Optimization Algorithm, for feature selection in chronic disease prediction. The…

Neural and Evolutionary Computing · Computer Science 2024-01-12 Abeer Dyoub , Ivan Letteri

A method to identify probable diseases from the unstructured textual input (eg, health forum posts) by incorporating a lexicographic and semantic feature based two-phase text classification module and a symptom-disease correlation-based…

Information Retrieval · Computer Science 2024-09-05 Fahim Faisal , Shafkat Ahmed Bhuiyan , Abu Raihan Mostofa Kamal

Change point detection is a crucial aspect of analyzing time series data, as the presence of a change point indicates an abrupt and significant change in the process generating the data. While many algorithms for the problem of change point…

Machine Learning · Computer Science 2023-05-23 Mario Krause

In the field of quality of health care measurement, one approach to assessing patient sickness at admission involves a logistic regression of mortality within 30 days of admission on a fairly large number of sickness indicators (on the…

Applications · Statistics 2009-08-18 D. Fouskakis , I. Ntzoufras , D. Draper

This work is motivated by learning the individualized minimal clinically important difference, a vital concept to assess clinical importance in various biomedical studies. We formulate the scientific question into a high-dimensional…

Methodology · Statistics 2023-03-28 Huijie Feng , Jingyi Duan , Yang Ning , Jiwei Zhao

Early detection of skin cancers like melanoma is crucial to ensure high chances of survival for patients. Clinical application of Deep Learning (DL)-based Decision Support Systems (DSS) for skin cancer screening has the potential to improve…

Computer Vision and Pattern Recognition · Computer Science 2021-03-10 Adriano Lucieri , Andreas Dengel , Sheraz Ahmed

High-performance deep learning methods typically rely on large annotated training datasets, which are difficult to obtain in many clinical applications due to the high cost of medical image labeling. Existing data assessment methods…

Computer Vision and Pattern Recognition · Computer Science 2022-09-30 Chun-Yin Huang , Qi Lei , Xiaoxiao Li

In a world where Machine Learning (ML) is increasingly deployed to support decision-making in critical domains, providing decision-makers with explainable, stable, and relevant inputs becomes fundamental. Understanding how machine learning…

Machine Learning · Computer Science 2024-08-07 Karol Capała , Paulina Tworek , Jose Sousa

Bayesian inference with Markov Chain Monte Carlo (MCMC) is challenging when the likelihood function is irregular and expensive to compute. We explore several sampling algorithms that make use of subset evaluations to reduce computational…

Machine Learning · Statistics 2025-05-16 Conor Rosato , Harvinder Lehal , Simon Maskell , Lee Devlin , Malcolm Strens

In biomedical studies, it is often desirable to characterize the interactive mode of multiple disease outcomes beyond their marginal risk. Ising model is one of the most popular choices serving for this purpose. Nevertheless, learning…

Methodology · Statistics 2023-11-28 Daiqing Wu , Molei Liu

Identifying measurable genetic indicators (or biomarkers) of a specific condition of a biological system is a key element of precision medicine. Indeed it allows to tailor diagnostic, prognostic and treatment choice to individual…

Machine Learning · Statistics 2016-12-16 Chloé-Agathe Azencott

Medical imaging is an essential tool in many areas of medical applications, used for both diagnosis and treatment. However, reading medical images and making diagnosis or treatment recommendations require specially trained medical…

Computer Vision and Pattern Recognition · Computer Science 2019-03-13 Wentao Zhu

The prediction of disease risk factors can screen vulnerable groups for effective prevention and treatment, so as to reduce their morbidity and mortality. Machine learning has a great demand for high-quality labeling information, and…

Machine Learning · Computer Science 2024-06-26 Yang Lin , Muqing Li , Ziyi Zhu , Yinqiu Feng , Lingxi Xiao , Zexi Chen

General unsupervised learning is a long-standing conceptual problem in machine learning. Supervised learning is successful because it can be solved by the minimization of the training error cost function. Unsupervised learning is not as…

Machine Learning · Computer Science 2015-12-04 Ilya Sutskever , Rafal Jozefowicz , Karol Gregor , Danilo Rezende , Tim Lillicrap , Oriol Vinyals

Researchers often face data fusion problems, where multiple data sources are available, each capturing a distinct subset of variables. While problem formulations typically take the data as given, in practice, data acquisition can be an…

Machine Learning · Computer Science 2021-11-02 Shantanu Gupta , Zachary C. Lipton , David Childers