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Denoising diffusion probabilistic models (DDPMs) have achieved unprecedented success in computer vision. However, they remain underutilized in medical imaging, a field crucial for disease diagnosis and treatment planning. This is primarily…
Simulation-based ultrasound training can be an essential educational tool. Realistic ultrasound image appearance with typical speckle texture can be modeled as convolution of a point spread function with point scatterers representing tissue…
Deep learning has emerged as a powerful artificial intelligence tool to interpret medical images for a growing variety of applications. However, the paucity of medical imaging data with high-quality annotations that is necessary for…
Flow-Imaging Microscopy (FIM) is commonly used in both academia and industry to characterize subvisible particles (those $\le 25 \mu m$ in size) in protein therapeutics. Pharmaceutical companies are required to record vast volumes of FIM…
Decoding brain signals accurately and efficiently is crucial for intra-cortical brain-computer interfaces. Traditional decoding approaches based on neural activity vector features suffer from low accuracy, whereas deep learning based…
Spiking neural networks are motivated from principles of neural systems and may possess unexplored advantages in the context of machine learning. A class of \textit{convolutional spiking neural networks} is introduced, trained to detect…
Multiple sclerosis is one of the most common chronic neurological diseases affecting the central nervous system. Lesions produced by the MS can be observed through two modalities of magnetic resonance (MR), known as T2W and FLAIR sequences,…
Advances in endoscopy use in surgeries face challenges like inadequate lighting. Deep learning, notably the Denoising Diffusion Probabilistic Model (DDPM), holds promise for low-light image enhancement in the medical field. However, DDPMs…
Convolutional Neural Networks (CNNs) have been recently employed to solve problems from both the computer vision and medical image analysis fields. Despite their popularity, most approaches are only able to process 2D images while most…
In medical-data driven learning, 3D convolutional neural networks (CNNs) have started to show superior performance to 2D CNNs in numerous deep learning tasks, proving the added value of 3D spatial information in feature representation.…
Diffusion MRI is a non-invasive, in-vivo biomedical imaging method for mapping tissue microstructure. Applications include structural connectivity imaging of the human brain and detecting microstructural neural changes. However, acquiring…
Accurate segmentation of punctate white matter lesions (PWML) in preterm neonates by an automatic algorithm can better assist doctors in diagnosis. However, the existing algorithms have many limitations, such as low detection accuracy and…
Fluorescence microscopy plays an important role in biomedical research. The depth-variant point spread function (PSF) of a fluorescence microscope produces low-quality images especially in the out-of-focus regions of thick specimens.…
Spiking neural networks (SNNs) can be used in low-power and embedded systems (such as emerging neuromorphic chips) due to their event-based nature. Also, they have the advantage of low computation cost in contrast to conventional artificial…
We present a physics-informed deep learning framework to address common limitations in Confocal Laser Scanning Microscopy (CLSM), such as diffraction limited resolution, noise, and undersampling due to low laser power conditions. The…
Hyperspectral imagery is rich in spatial and spectral information. Using 3D-CNN can simultaneously acquire features of spatial and spectral dimensions to facilitate classification of features, but hyperspectral image information spectral…
Convolutional neural networks (CNNs) have been the de facto standard in a diverse set of computer vision tasks for many years. Especially, deep neural networks based on seminal architectures such as U-shaped models with skip-connections or…
Deep learning has achieved remarkable success in medical image analysis, however its adoption in clinical practice is limited by a lack of interpretability. These models often make correct predictions without explaining their reasoning.…
Fluorescence lifetime imaging (FLI) has been receiving increased attention in recent years as a powerful diagnostic technique in biological and medical research. However, existing FLI systems often suffer from a tradeoff between processing…
Differential dynamic microscopy (DDM) typically relies on movies containing hundreds or thousands of frames to accurately quantify motion in soft matter systems. Using movies much shorter in duration produces noisier and less accurate…