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Denoising diffusion probabilistic models (DDPMs) have achieved unprecedented success in computer vision. However, they remain underutilized in medical imaging, a field crucial for disease diagnosis and treatment planning. This is primarily…

Image and Video Processing · Electrical Eng. & Systems 2025-08-22 Hongxu Jiang , Muhammad Imran , Teng Zhang , Yuyin Zhou , Muxuan Liang , Kuang Gong , Wei Shao

Simulation-based ultrasound training can be an essential educational tool. Realistic ultrasound image appearance with typical speckle texture can be modeled as convolution of a point spread function with point scatterers representing tissue…

Computer Vision and Pattern Recognition · Computer Science 2020-06-19 Lin Zhang , Valery Vishnevskiy , Orcun Goksel

Deep learning has emerged as a powerful artificial intelligence tool to interpret medical images for a growing variety of applications. However, the paucity of medical imaging data with high-quality annotations that is necessary for…

Computer Vision and Pattern Recognition · Computer Science 2018-10-02 Faisal Mahmood , Richard Chen , Sandra Sudarsky , Daphne Yu , Nicholas J. Durr

Flow-Imaging Microscopy (FIM) is commonly used in both academia and industry to characterize subvisible particles (those $\le 25 \mu m$ in size) in protein therapeutics. Pharmaceutical companies are required to record vast volumes of FIM…

Quantitative Methods · Quantitative Biology 2017-09-04 Christopher P. Calderon , Austin L. Daniels , Theodore W. Randolph

Decoding brain signals accurately and efficiently is crucial for intra-cortical brain-computer interfaces. Traditional decoding approaches based on neural activity vector features suffer from low accuracy, whereas deep learning based…

Human-Computer Interaction · Computer Science 2025-04-15 Song Yang , Haotian Fu , Herui Zhang , Peng Zhang , Wei Li , Dongrui Wu

Spiking neural networks are motivated from principles of neural systems and may possess unexplored advantages in the context of machine learning. A class of \textit{convolutional spiking neural networks} is introduced, trained to detect…

Neural and Evolutionary Computing · Computer Science 2018-08-27 Daniel J. Saunders , Hava T. Siegelmann , Robert Kozma , Miklós Ruszinkó

Multiple sclerosis is one of the most common chronic neurological diseases affecting the central nervous system. Lesions produced by the MS can be observed through two modalities of magnetic resonance (MR), known as T2W and FLAIR sequences,…

Signal Processing · Electrical Eng. & Systems 2022-12-16 Antonio Falvo , Danilo Comminiello , Simone Scardapane , Michele Scarpiniti , Aurelio Uncini

Advances in endoscopy use in surgeries face challenges like inadequate lighting. Deep learning, notably the Denoising Diffusion Probabilistic Model (DDPM), holds promise for low-light image enhancement in the medical field. However, DDPMs…

Image and Video Processing · Electrical Eng. & Systems 2024-05-20 Tong Chen , Qingcheng Lyu , Long Bai , Erjian Guo , Huxin Gao , Xiaoxiao Yang , Hongliang Ren , Luping Zhou

Convolutional Neural Networks (CNNs) have been recently employed to solve problems from both the computer vision and medical image analysis fields. Despite their popularity, most approaches are only able to process 2D images while most…

Computer Vision and Pattern Recognition · Computer Science 2016-06-16 Fausto Milletari , Nassir Navab , Seyed-Ahmad Ahmadi

In medical-data driven learning, 3D convolutional neural networks (CNNs) have started to show superior performance to 2D CNNs in numerous deep learning tasks, proving the added value of 3D spatial information in feature representation.…

Image and Video Processing · Electrical Eng. & Systems 2024-01-24 Xin Wang , Ruisheng Su , Weiyi Xie , Wenjin Wang , Yi Xu , Ritse Mann , Jungong Han , Tao Tan

Diffusion MRI is a non-invasive, in-vivo biomedical imaging method for mapping tissue microstructure. Applications include structural connectivity imaging of the human brain and detecting microstructural neural changes. However, acquiring…

Image and Video Processing · Electrical Eng. & Systems 2023-10-09 Amir Sadikov , Xinlei Pan , Hannah Choi , Lanya T. Cai , Pratik Mukherjee

Accurate segmentation of punctate white matter lesions (PWML) in preterm neonates by an automatic algorithm can better assist doctors in diagnosis. However, the existing algorithms have many limitations, such as low detection accuracy and…

Image and Video Processing · Electrical Eng. & Systems 2019-10-23 Yalong Liu , Jie Li , Miaomiao Wang , Zhicheng Jiao , Jian Yang , Xianjun Li

Fluorescence microscopy plays an important role in biomedical research. The depth-variant point spread function (PSF) of a fluorescence microscope produces low-quality images especially in the out-of-focus regions of thick specimens.…

Image and Video Processing · Electrical Eng. & Systems 2019-07-09 Da He , De Cai , Jiasheng Zhou , Jiajia Luo , Sung-Liang Chen

Spiking neural networks (SNNs) can be used in low-power and embedded systems (such as emerging neuromorphic chips) due to their event-based nature. Also, they have the advantage of low computation cost in contrast to conventional artificial…

Computer Vision and Pattern Recognition · Computer Science 2021-01-20 Ali Samadzadeh , Fatemeh Sadat Tabatabaei Far , Ali Javadi , Ahmad Nickabadi , Morteza Haghir Chehreghani

We present a physics-informed deep learning framework to address common limitations in Confocal Laser Scanning Microscopy (CLSM), such as diffraction limited resolution, noise, and undersampling due to low laser power conditions. The…

Materials Science · Physics 2025-01-27 Zaheer Ahmad , Junaid Shabeer , Usman Saleem , Tahir Qadeer , Abdul Sami , Zahira El Khalidi , Saad Mehmood

Hyperspectral imagery is rich in spatial and spectral information. Using 3D-CNN can simultaneously acquire features of spatial and spectral dimensions to facilitate classification of features, but hyperspectral image information spectral…

Image and Video Processing · Electrical Eng. & Systems 2022-02-15 Guandong Li , Chunju Zhang

Convolutional neural networks (CNNs) have been the de facto standard in a diverse set of computer vision tasks for many years. Especially, deep neural networks based on seminal architectures such as U-shaped models with skip-connections or…

Image and Video Processing · Electrical Eng. & Systems 2022-08-02 Reza Azad , Moein Heidari , Moein Shariatnia , Ehsan Khodapanah Aghdam , Sanaz Karimijafarbigloo , Ehsan Adeli , Dorit Merhof

Deep learning has achieved remarkable success in medical image analysis, however its adoption in clinical practice is limited by a lack of interpretability. These models often make correct predictions without explaining their reasoning.…

Image and Video Processing · Electrical Eng. & Systems 2025-10-03 Jhonatan Contreras , Thomas Bocklitz

Fluorescence lifetime imaging (FLI) has been receiving increased attention in recent years as a powerful diagnostic technique in biological and medical research. However, existing FLI systems often suffer from a tradeoff between processing…

Image and Video Processing · Electrical Eng. & Systems 2025-11-10 Yang Lin , Paul Mos , Andrei Ardelean , Claudio Bruschini , Edoardo Charbon

Differential dynamic microscopy (DDM) typically relies on movies containing hundreds or thousands of frames to accurately quantify motion in soft matter systems. Using movies much shorter in duration produces noisier and less accurate…

Soft Condensed Matter · Physics 2024-11-05 Gildardo Martinez , Justin Siu , Steven Dang , Dylan Gage , Emma Kao , Juan Carlos Avila , Ruilin You , Ryan McGorty