Related papers: A Statistical Framework for Optimizing and Evaluat…

This study presents a comparison of quantitative MRI methods based on an efficiency metric that quantifies their intrinsic ability to extract information about tissue parameters. Under a regime of unbiased parameter estimates, an intrinsic…

Magnetic resonance (MR) fingerprinting is a new quantitative imaging paradigm, which simultaneously acquires multiple MR tissue parameter maps in a single experiment. In this paper, we present an estimation-theoretic framework to perform…

We propose an unsupervised convolutional neural network (CNN) for relaxation parameter estimation. This network incorporates signal relaxation and Bloch simulations while taking advantage of residual learning and spatial relations across…

Magnetic Resonance Fingerprinting (MRF) is a method to extract quantitative tissue properties such as T1 and T2 relaxation rates from arbitrary pulse sequences using conventional magnetic resonance imaging hardware. MRF pulse sequences have…

High-resolution (HR) quantitative MRI (qMRI) relaxometry provides objective tissue characterization but remains clinically underutilized due to lengthy acquisition times. We propose a physics-informed, self-supervised framework for qMRI…

In this paper, we propose the use of Recurrent Inference Machines (RIMs) to perform T1 and T2 mapping. The RIM is a neural network framework that learns an iterative inference process based on the signal model, similar to conventional…

Cardiac T1 mapping provides critical quantitative insights into myocardial tissue composition, enabling the assessment of pathologies such as fibrosis, inflammation, and edema. However, the inherently dynamic nature of the heart imposes…

Purpose: In many clinical MRI scenarios, existing imaging information can be used to significantly shorten acquisition time or to improve Signal to Noise Ratio (SNR). In this paper the authors present a framework for fast MRI by exploiting…

Magnetic Resonance Imaging (MRI) is one of the most dynamic and safe imaging techniques available for clinical applications. However, the rather slow speed of MRI acquisitions limits the patient throughput and potential indi cations.…

Purpose: Recent work highlights the breadth of reported spin-lattice relaxation rates ($R_1$) for individual tissues. One potential source of variation is the protocol used to determine $R_1$. The methodological dependence of R1 and…

Quantitative magnetic resonance imaging (qMRI) is increasingly investigated for use in a variety of clinical tasks from diagnosis, through staging, to treatment monitoring. However, experiment design in qMRI, the identification of the…

Recovering the T2 distribution from multi-echo T2 magnetic resonance (MR) signals is challenging but has high potential as it provides biomarkers characterizing the tissue micro-structure, such as the myelin water fraction (MWF). In this…

Purpose: This study demonstrated an MR signal multitask learning method for 3D simultaneous segmentation and relaxometry of human brain tissues. Materials and Methods: A 3D inversion-prepared balanced steady-state free precession sequence…

Purpose: The analysis of optimized spin ensemble trajectories for relaxometry in the hybrid state. Methods: First, we constructed visual representations to elucidate the differential equation that governs spin dynamics in hybrid state.…

Quantitative magnetic resonance (MR) T1\r{ho} mapping is a promising approach for characterizing intrinsic tissue-dependent information. However, long scan time significantly hinders its widespread applications. Recently, low-rank tensor…

Purpose: To develop neural network (NN)-based quantitative MRI parameter estimators with minimal bias and a variance close to the Cram\'er-Rao bound. Theory and Methods: We generalize the mean squared error loss to control the bias and…

In nonlinear deterministic parameter estimation, the maximum likelihood estimator (MLE) is unable to attain the Cramer-Rao lower bound at low and medium signal-to-noise ratios (SNR) due the threshold and ambiguity phenomena. In order to…

Purpose: Investigation of the feasibility of the R2* mapping techniques by using latest theoretical models corrected for confounding factors and optimized for signal to noise ratio. Theory and Methods: The improvement of the performance of…

Task-adapted compressed sensing magnetic resonance imaging (CS-MRI) is emerging to address the specific demands of downstream clinical tasks with significantly fewer k-space measurements than required by Nyquist sampling. However, existing…

Accurate thalamic nuclei segmentation is crucial for understanding neurological diseases, brain functions, and guiding clinical interventions. However, the optimal inputs for segmentation remain unclear. This study systematically evaluates…