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Accurate image registration is pivotal in biomedical image analysis, where selecting suitable registration algorithms demands careful consideration. While numerous algorithms are available, the evaluation metrics to assess their performance…

With the increasing availability of new image registration approaches, an unbiased evaluation is becoming more needed so that clinicians can choose the most suitable approaches for their applications. Current evaluations typically use…

Computer Vision and Pattern Recognition · Computer Science 2020-03-24 Jie Luo , Guangshen Ma , Sarah Frisken , Parikshit Juvekar , Nazim Haouchine , Zhe Xu , Yiming Xiao , Alexandra Golby , Patrick Codd , Masashi Sugiyama , William Wells

Deep learning has revolutionized medical image registration by achieving unprecedented speeds, yet its clinical application is hindered by a limited ability to generalize beyond the training domain, a critical weakness given the typically…

Computer Vision and Pattern Recognition · Computer Science 2026-02-02 Fengting Zhang , Yue He , Qinghao Liu , Yaonan Wang , Xiang Chen , Hang Zhang

Multimodal image registration is a challenging but essential step for numerous image-guided procedures. Most registration algorithms rely on the computation of complex, frequently non-differentiable similarity metrics to deal with the…

Computer Vision and Pattern Recognition · Computer Science 2023-07-20 Matteo Ronchetti , Wolfgang Wein , Nassir Navab , Oliver Zettinig , Raphael Prevost

The ability for a machine learning model to cope with differences in training and deployment conditions--e.g. in the presence of distribution shift or the generalization to new classes altogether--is crucial for real-world use cases.…

Machine Learning · Computer Science 2023-12-14 Jenny Hamer , Eleni Triantafillou , Bart van Merriënboer , Stefan Kahl , Holger Klinck , Tom Denton , Vincent Dumoulin

Multiple instance learning (MIL) significantly reduced annotation costs via bag-level weak labels for large-scale images, such as histopathological whole slide images (WSIs). However, its adaptability to continual tasks with minimal…

Computer Vision and Pattern Recognition · Computer Science 2025-07-09 Byung Hyun Lee , Wongi Jeong , Woojae Han , Kyoungbun Lee , Se Young Chun

Purpose: In this work, we present a collaboration to create a validation dataset of pathologist annotations for algorithms that process whole slide images (WSIs). We focus on data collection and evaluation of algorithm performance in the…

Image annotation and large annotated datasets are crucial parts within the Computer Vision and Artificial Intelligence fields.At the same time, it is well-known and acknowledged by the research community that the image annotation process is…

Computer Vision and Pattern Recognition · Computer Science 2021-08-27 Tuomo Lahtinen , Hannu Turtiainen , Andrei Costin

Image recognition techniques heavily rely on abundant labeled data, particularly in medical contexts. Addressing the challenges associated with obtaining labeled data has led to the prominence of self-supervised learning and semi-supervised…

Computer Vision and Pattern Recognition · Computer Science 2024-04-17 Hao Feng , Yuanzhe Jia , Ruijia Xu , Mukesh Prasad , Ali Anaissi , Ali Braytee

We built the largest database for kinship recognition. The data were labeled using a novel clustering algorithm that used label proposals as side information to guide more accurate clusters. Great savings in time and human input was had.…

Computer Vision and Pattern Recognition · Computer Science 2021-02-18 Joseph P Robinson

Retinal anomaly detection plays a pivotal role in screening ocular and systemic diseases. Despite its significance, progress in the field has been hindered by the absence of a comprehensive and publicly available benchmark, which is…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Chenyu Lian , Hong-Yu Zhou , Zhanli Hu , Jing Qin

Registration involving one or more images containing pathologies is challenging, as standard image similarity measures and spatial transforms cannot account for common changes due to pathologies. Low-rank/Sparse (LRS) decomposition removes…

Computer Vision and Pattern Recognition · Computer Science 2017-04-04 Xu Han , Xiao Yang , Stephen Aylward , Roland Kwitt , Marc Niethammer

Robust mammography registration is essential for clinical applications like tracking disease progression and monitoring longitudinal changes in breast tissue. However, progress has been limited by the absence of public datasets and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-22 Svetlana Krasnova , Emiliya Starikova , Ilia Naletov , Andrey Krylov , Dmitry Sorokin

In human neuroimaging studies, atlas registration enables mapping MRI scans to a common coordinate frame, which is necessary to aggregate data from multiple subjects. Machine learning registration methods have achieved excellent speed and…

Computer Vision and Pattern Recognition · Computer Science 2024-07-08 Karthik Gopinath , Xiaoling Hu , Malte Hoffmann , Oula Puonti , Juan Eugenio Iglesias

Pathological diagnosis is highly reliant on image analysis, where Regions of Interest (ROIs) serve as the primary basis for diagnostic evidence, while whole-slide image (WSI)-level tasks primarily capture aggregated patterns. To extract…

Computer Vision and Pattern Recognition · Computer Science 2026-05-08 Enhui Chai , Sicheng Chen , Tianyi Zhang , Xingyu Li , Tianxiang Cui

Image registration is a fundamental task in medical image analysis. Deformations are often closely related to the morphological characteristics of tissues, making accurate feature extraction crucial. Recent weakly supervised methods improve…

Computer Vision and Pattern Recognition · Computer Science 2025-09-18 Yue He , Min Liu , Qinghao Liu , Jiazheng Wang , Yaonan Wang , Hang Zhang , Xiang Chen

Whole slide images, with their gigapixel-scale panoramas of tissue samples, are pivotal for precise disease diagnosis. However, their analysis is hindered by immense data size and scarce annotations. Existing MIL methods face challenges due…

Computer Vision and Pattern Recognition · Computer Science 2026-02-26 Weiyi Wu , Xinwen Xu , Chongyang Gao , Xingjian Diao , Siting Li , Jiang Gui

Retinal image registration plays an important role in the ophthalmological diagnosis process. Since there exist variances in viewing angles and anatomical structures across different retinal images, keypoint-based approaches become the…

Computer Vision and Pattern Recognition · Computer Science 2024-10-17 Yepeng Liu , Baosheng Yu , Tian Chen , Yuliang Gu , Bo Du , Yongchao Xu , Jun Cheng

Deep Learning in Image Registration (DLIR) methods have been tremendously successful in image registration due to their speed and ability to incorporate weak label supervision at training time. However, existing DLIR methods forego many of…

Computer Vision and Pattern Recognition · Computer Science 2025-05-06 Rohit Jena , Pratik Chaudhari , James C. Gee

Image registration is an essential step in many medical image analysis tasks. Traditional methods for image registration are primarily optimization-driven, finding the optimal deformations that maximize the similarity between two images.…

Computer Vision and Pattern Recognition · Computer Science 2024-10-14 Shanlin Sun , Kun Han , Chenyu You , Hao Tang , Deying Kong , Junayed Naushad , Xiangyi Yan , Haoyu Ma , Pooya Khosravi , James S. Duncan , Xiaohui Xie
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