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Chest X-ray scan is a most often used modality by radiologists to diagnose many chest related diseases in their initial stages. The proposed system aids the radiologists in making decision about the diseases found in the scans more…

Image and Video Processing · Electrical Eng. & Systems 2020-08-07 Ahmed Rasheed , Muhammad Shahzad Younis , Muhammad Bilal , Maha Rasheed

Machine learning can precisely identify different cancer tumors at any stage by classifying cancerous and healthy samples based on their genomic profile. We have developed novel methods of MLAC (Machine Learning Against Cancer) achieving…

Genomics · Quantitative Biology 2020-09-15 Arash Hooshmand

Recent advances in high-throughput genomic technologies coupled with exponential increases in computer processing and memory have allowed us to interrogate the complex aberrant molecular underpinnings of human disease from a genome-wide…

We consider the analysis of high dimensional data given in the form of a matrix with columns consisting of observations and rows consisting of features. Often the data is such that the observations do not reside on a regular grid, and the…

Machine Learning · Statistics 2017-08-22 Gal Mishne , Ronen Talmon , Israel Cohen , Ronald R. Coifman , Yuval Kluger

Deep learning segmentation and fluorescence imaging techniques allow the cellular morphology of living embryos to be constructed spatiotemporally. These development processes involve numerous molecules distributed at the subcellular scale,…

In digital pathology tasks, transformers have achieved state-of-the-art results, surpassing convolutional neural networks (CNNs). However, transformers are usually complex and resource intensive. In this study, we developed a novel and…

Image and Video Processing · Electrical Eng. & Systems 2023-05-04 Min Cen , Xingyu Li , Bangwei Guo , Jitendra Jonnagaddala , Hong Zhang , Xu Steven Xu

Identifying concentrations of components from an observed mixture is a fundamental problem in signal processing. It has diverse applications in fields ranging from hyperspectral imaging to denoising biomedical sensors. This paper focuses on…

Computational Engineering, Finance, and Science · Computer Science 2016-11-17 Shahin Mohammadi , Neta Zuckerman , Andrea Goldsmith , Ananth Grama

Circulating Tumor Cells (CTCs) bear great promise as biomarkers in tumor prognosis. However, the process of identification and later enumeration of CTCs require manual labor, which is error-prone and time-consuming. The recent developments…

Computer Vision and Pattern Recognition · Computer Science 2022-08-08 Elena Alexander , Kam W. Leong , Andrew F. Laine

Pancreatic cancer is one of the most malignant cancers in the world, which deteriorates rapidly with very high mortality. The rapid on-site evaluation (ROSE) technique innovates the workflow by immediately analyzing the fast stained…

Image and Video Processing · Electrical Eng. & Systems 2021-12-28 Tianyi Zhang , Yunlu Feng , Yu Zhao , Guangda Fan , Aiming Yang , Shangqin Lyu , Peng Zhang , Fan Song , Chenbin Ma , Yangyang Sun , Youdan Feng , Guanglei Zhang

Classifying breast cancer molecular subtypes is crucial for tailoring treatment strategies. While immunohistochemistry (IHC) and gene expression profiling are standard methods for molecular subtyping, IHC can be subjective, and gene…

Image and Video Processing · Electrical Eng. & Systems 2024-09-17 Masoud Tafavvoghi , Anders Sildnes , Mehrdad Rakaee , Nikita Shvetsov , Lars Ailo Bongo , Lill-Tove Rasmussen Busund , Kajsa Møllersen

Breast cancer is a major concern for women's health globally, with axillary lymph node (ALN) metastasis identification being critical for prognosis evaluation and treatment guidance. This paper presents a deep learning (DL) classification…

Image and Video Processing · Electrical Eng. & Systems 2023-10-09 Glejdis Shkëmbi , Johanna P. Müller , Zhe Li , Katharina Breininger , Peter Schüffler , Bernhard Kainz

With the development of computer technology, various models have emerged in artificial intelligence. The transformer model has been applied to the field of computer vision (CV) after its success in natural language processing (NLP).…

Computer Vision and Pattern Recognition · Computer Science 2022-07-05 Ruina Sun , Yuexin Pang

Cancer is a complex disease driven by dynamic regulatory shifts that cannot be fully captured by individual molecular profiling. We employ a data-driven approach to construct a coarse-grained dynamic network model based on hallmark…

Quantitative Methods · Quantitative Biology 2025-02-28 Jiahe Wang , Yan Wu , Yuke Hou , Yang Li , Dachuan Xu , Changjing Zhuge , Yue Han

Colon cancer also known as Colorectal cancer, is one of the most malignant types of cancer worldwide. Early-stage detection of colon cancer is highly crucial to prevent its deterioration. This research presents a hybrid multi-scale deep…

Computer Vision and Pattern Recognition · Computer Science 2025-09-04 Sadra Saremi , Amirhossein Ahmadkhan Kordbacheh

Breast cancer is one of the most common cancers affecting women worldwide. They include a group of malignant neoplasms with a variety of biological, clinical, and histopathological characteristics. There are more than 35 different…

Image and Video Processing · Electrical Eng. & Systems 2023-08-23 Abubakr Shafique , Ricardo Gonzalez , Liron Pantanowitz , Puay Hoon Tan , Alberto Machado , Ian A Cree , Hamid R. Tizhoosh

The metabolic wiring of patient cells is altered drastically in many diseases, including cancer. Understanding the nature of such changes may pave the way for new therapeutic opportunities, as well as the development of personalized…

Molecular Networks · Quantitative Biology 2020-02-12 Ali Cakmak , M. Hasan Celik

Supervised deep learning models often achieve excellent performance within their training distribution but struggle to generalize beyond it. In cancer histopathology, for example, a convolutional neural network (CNN) may classify cancer…

Computer Vision and Pattern Recognition · Computer Science 2026-01-22 Justin Cheung , Samuel Savine , Calvin Nguyen , Lin Lu , Alhassan S. Yasin

The placenta is a complex organ, playing multiple roles during fetal development. Very little is known about the association between placental morphological abnormalities and fetal physiology. In this work, we present an open sourced,…

Computer Vision and Pattern Recognition · Computer Science 2018-05-29 Michael Ferlaino , Craig A. Glastonbury , Carolina Motta-Mejia , Manu Vatish , Ingrid Granne , Stephen Kennedy , Cecilia M. Lindgren , Christoffer Nellåker

Accurate classification of white blood cells in peripheral blood is essential for diagnosing hematological diseases. Due to constantly evolving clinical settings, data sources, and disease classifications, it is necessary to update machine…

Computer Vision and Pattern Recognition · Computer Science 2023-08-25 Ario Sadafi , Raheleh Salehi , Armin Gruber , Sayedali Shetab Boushehri , Pascal Giehr , Nassir Navab , Carsten Marr

The majority of cancer treatments end in failure due to Intra-Tumor Heterogeneity (ITH). ITH in cancer is represented by clonal evolution where different sub-clones compete with each other for resources under conditions of Darwinian natural…