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Anticipating the low energy arrangements of atoms in space is an indispensable scientific task. Modern stochastic approaches to searching for these configurations depend on the optimisation of structures to nearby local minima in the energy…

Materials Science · Physics 2019-02-07 Chris J. Pickard

A single gene can encode for different protein versions through a process called alternative splicing. Since proteins play major roles in cellular functions, aberrant splicing profiles can result in a variety of diseases, including cancers.…

Genomics · Quantitative Biology 2021-03-09 Alvin Chan , Anna Korsakova , Yew-Soon Ong , Fernaldo Richtia Winnerdy , Kah Wai Lim , Anh Tuan Phan

The primary step in search of the gene prediction is an identification of the coding region from genomic DNA sequence. Gene structure in the case of a eukaryotic organism is composed of promoter, intron, start codon, exons, stop codon, etc.…

Genomics · Quantitative Biology 2019-07-23 Srabanti Maji , Soumen Kanrar

To address the trade-off between computational efficiency and adherence to Kolmogorov-Arnold Network (KAN) principles, we propose TruKAN, a new architecture based on the KAN structure and learnable activation functions. TruKAN replaces the…

Computer Vision and Pattern Recognition · Computer Science 2026-02-05 Ali Bayeh , Samira Sadaoui , Malek Mouhoub

An innovative physics-guided learning algorithm for predicting the mechanical response of materials and structures is proposed in this paper. The key concept of the proposed study is based on the fact that physics models are governed by…

Computational Engineering, Finance, and Science · Computer Science 2020-04-22 Houpu Yao , Yi Gao , Yongming Liu

Predicting properties of crystals from their structures is a fundamental yet challenging task in materials science. Unlike molecules, crystal structures exhibit infinite periodic arrangements of atoms, requiring methods capable of capturing…

Machine Learning · Computer Science 2025-09-29 Jianan Nie , Peiyao Xiao , Kaiyi Ji , Peng Gao

Biological functions of RNAs are determined by their three-dimensional (3D) structures. Thus, given the limited number of experimentally determined RNA structures, the prediction of RNA structures will facilitate elucidating RNA functions…

Machine Learning · Computer Science 2023-07-25 Shuo Zhang , Yang Liu , Lei Xie

Approximate computing offers promising energy efficiency benefits for error-tolerant applications, but discovering optimal approximations requires extensive design space exploration (DSE). Predicting the accuracy of circuits composed of…

Hardware Architecture · Computer Science 2026-03-20 Ondrej Vlcek , Vojtech Mrazek

The searching procedure of neural architecture search (NAS) is notoriously time consuming and cost prohibitive.To make the search space continuous, most existing gradient-based NAS methods relax the categorical choice of a particular…

Computer Vision and Pattern Recognition · Computer Science 2019-12-11 Shoufa Chen , Yunpeng Chen , Shuicheng Yan , Jiashi Feng

Hamiltonian matrix prediction is pivotal in computational chemistry, serving as the foundation for determining a wide range of molecular properties. While SE(3) equivariant graph neural networks have achieved remarkable success in this…

Machine Learning · Computer Science 2025-05-23 Erpai Luo , Xinran Wei , Lin Huang , Yunyang Li , Han Yang , Zaishuo Xia , Zun Wang , Chang Liu , Bin Shao , Jia Zhang

Few-shot fine-grained image classification aims to recognize subcategories with high visual similarity using only a limited number of annotated samples. Existing metric learning-based methods typically rely solely on spatial domain…

Computer Vision and Pattern Recognition · Computer Science 2026-04-17 Meijia Wang , Guochao Wang , Haozhen Chu , Bin Yao , Weichuan Zhang , Yuan Wang , Junpo Yang

Finite Element Analysis (FEA) is a powerful but computationally intensive method for simulating physical phenomena. Recent advancements in machine learning have led to surrogate models capable of accelerating FEA. Yet there are still…

Machine Learning · Computer Science 2025-02-18 Georgios Triantafyllou , Panagiotis G. Kalozoumis , George Dimas , Dimitris K. Iakovidis

In the present paper, we introduce a new neural network-based tool for the prediction of formation energies of atomic structures based on elemental and structural features of Voronoi-tessellated materials. We provide a concise overview of…

Materials Science · Physics 2023-03-17 Adam M. Krajewski , Jonathan W. Siegel , Jinchao Xu , Zi-Kui Liu

Probabilistic forecasts are essential for various downstream applications such as business development, traffic planning, and electrical grid balancing. Many of these probabilistic forecasts are performed on time series data that contain…

Machine Learning · Computer Science 2023-02-07 Benedikt Heidrich , Kaleb Phipps , Oliver Neumann , Marian Turowski , Ralf Mikut , Veit Hagenmeyer

Deep Neural Networks (DNN) achieve human level performance in many image analytics tasks but DNNs are mostly deployed to GPU platforms that consume a considerable amount of power. New hardware platforms using lower precision arithmetic…

Neural and Evolutionary Computing · Computer Science 2017-05-23 Antonio Jimeno Yepes , Jianbin Tang , Benjamin Scott Mashford

Designing RNA molecules has garnered recent interest in medicine, synthetic biology, biotechnology and bioinformatics since many functional RNA molecules were shown to be involved in regulatory processes for transcription, epigenetics and…

Machine Learning · Computer Science 2019-04-15 Frederic Runge , Danny Stoll , Stefan Falkner , Frank Hutter

RNA-Seq technology offers new high-throughput ways for transcript identification and quantification based on short reads, and has recently attracted great interest. The problem is usually modeled by a weighted splicing graph whose nodes…

Quantitative Methods · Quantitative Biology 2013-08-02 Alexandru I. Tomescu , Anna Kuosmanen , Romeo Rizzi , Veli Mäkinen

We propose StitchNet, a novel neural network creation paradigm that stitches together fragments (one or more consecutive network layers) from multiple pre-trained neural networks. StitchNet allows the creation of high-performing neural…

Machine Learning · Computer Science 2023-09-26 Surat Teerapittayanon , Marcus Comiter , Brad McDanel , H. T. Kung

Proteins are essential for maintaining life. For example, knowing the structure of a protein, cell regulatory mechanisms of organisms can be modeled, supporting the development of disease treatments or the understanding of relationships…

Biomolecules · Quantitative Biology 2019-01-07 Daniel Bonetti , Alexandre Delbem , Dorival Leão , Jochen Einbeck

Efficient inference of Convolutional Neural Networks is a thriving topic recently. It is desirable to achieve the maximal test accuracy under given inference budget constraints when deploying a pre-trained model. Network pruning is a…

Computer Vision and Pattern Recognition · Computer Science 2019-10-29 Ruizhe Zhao , Wayne Luk
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