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Large language model (LLM) agents are constrained by limited context windows, necessitating external memory systems for long-term information understanding. Current memory-augmented agents typically depend on pre-defined instructions and…

Computation and Language · Computer Science 2025-10-01 Yu Wang , Ryuichi Takanobu , Zhiqi Liang , Yuzhen Mao , Yuanzhe Hu , Julian McAuley , Xiaojian Wu

Sample efficiency is a fundamental challenge in de novo molecular design. Ideally, molecular generative models should learn to satisfy a desired objective under minimal oracle evaluations (computational prediction or wet-lab experiment).…

Biomolecules · Quantitative Biology 2023-05-26 Jeff Guo , Philippe Schwaller

Continual lifelong learning is an machine learning framework inspired by human learning, where learners are trained to continuously acquire new knowledge in a sequential manner. However, the non-stationary nature of streaming training data…

Machine Learning · Computer Science 2024-05-14 Xingyu Li , Bo Tang , Haifeng Li

In this paper, we propose a multi-timescale replay (MTR) buffer for improving continual learning in RL agents faced with environments that are changing continuously over time at timescales that are unknown to the agent. The basic MTR buffer…

Machine Learning · Computer Science 2020-04-17 Christos Kaplanis , Claudia Clopath , Murray Shanahan

Continual learning is the problem of learning new tasks or knowledge while protecting old knowledge and ideally generalizing from old experience to learn new tasks faster. Neural networks trained by stochastic gradient descent often degrade…

Machine Learning · Computer Science 2019-11-27 David Rolnick , Arun Ahuja , Jonathan Schwarz , Timothy P. Lillicrap , Greg Wayne

User behavior on online platforms is evolving, reflecting real-world changes in how people post, whether it's helpful messages or hate speech. Models that learn to capture this content can experience a decrease in performance over time due…

Machine Learning · Computer Science 2025-11-04 Yasas Senarath , Hemant Purohit

Deep Reinforcement Learning agents often suffer from catastrophic forgetting, forgetting previously found solutions in parts of the input space when training on new data. Replay Memories are a common solution to the problem, decorrelating…

Machine Learning · Computer Science 2023-08-29 Muhammad Burhan Hafez , Tilman Immisch , Tom Weber , Stefan Wermter

Continual Learning requires the model to learn from a stream of dynamic, non-stationary data without forgetting previous knowledge. Several approaches have been developed in the literature to tackle the Continual Learning challenge. Among…

Machine Learning · Computer Science 2022-11-30 Gabriele Merlin , Vincenzo Lomonaco , Andrea Cossu , Antonio Carta , Davide Bacciu

Large Language Models (LLMs) based agents excel at diverse tasks, yet they suffer from brittle procedural memory that is manually engineered or entangled in static parameters. In this work, we investigate strategies to endow agents with a…

Computation and Language · Computer Science 2026-04-16 Runnan Fang , Yuan Liang , Xiaobin Wang , Jialong Wu , Shuofei Qiao , Pengjun Xie , Fei Huang , Huajun Chen , Ningyu Zhang

Continual learning, the setting where a learning agent is faced with a never ending stream of data, continues to be a great challenge for modern machine learning systems. In particular the online or "single-pass through the data" setting…

Machine Learning · Computer Science 2019-10-31 Rahaf Aljundi , Lucas Caccia , Eugene Belilovsky , Massimo Caccia , Min Lin , Laurent Charlin , Tinne Tuytelaars

Traditional memory writing operations proceed one bit at a time, where e.g. an individual magnetic domain is force-flipped by a localized external field. One way to increase material storage capacity would be to write several bits at a time…

Soft Condensed Matter · Physics 2022-05-10 Théo Jules , Laura Michel , Adèle Douin , Frédéric Lechenault

A remarkable capacity of the brain is its ability to autonomously reorganize memories during offline periods. Memory replay, a mechanism hypothesized to underlie biological offline learning, has inspired offline methods for reducing…

Neural and Evolutionary Computing · Computer Science 2023-01-18 Zhenglong Zhou , Geshi Yeung , Anna C. Schapiro

Experience replay (ER) is a fundamental component of off-policy deep reinforcement learning (RL). ER recalls experiences from past iterations to compute gradient estimates for the current policy, increasing data-efficiency. However, the…

Machine Learning · Computer Science 2019-05-21 Guido Novati , Petros Koumoutsakos

Memory replay may be key to learning in biological brains, which manage to learn new tasks continually without catastrophically interfering with previous knowledge. On the other hand, artificial neural networks suffer from catastrophic…

Machine Learning · Computer Science 2022-01-06 Haitz Sáez de Ocáriz Borde

Episodic control, inspired by the role of episodic memory in the human brain, has been shown to improve the sample inefficiency of model-free reinforcement learning by reusing high-return past experiences. However, the memory growth of…

Systems and Control · Electrical Eng. & Systems 2024-07-24 Mukul Chodhary , Kevin Octavian , SooJean Han

AI agents are increasingly used in long, multi-turn workflows in both research and enterprise settings. As interactions grow, agent behavior often degrades due to loss of constraint focus, error accumulation, and memory-induced drift. This…

Neurons and Cognition · Quantitative Biology 2026-02-05 Fouad Bousetouane

Effective decision-making in partially observable environments demands robust memory management. Despite their success in supervised learning, current deep-learning memory models struggle in reinforcement learning environments that are…

Machine Learning · Computer Science 2024-10-15 Hung Le , Kien Do , Dung Nguyen , Sunil Gupta , Svetha Venkatesh

Reinforcement learning (RL) is a branch of machine learning which is employed to solve various sequential decision making problems without proper supervision. Due to the recent advancement of deep learning, the newly proposed Deep-RL…

Artificial Intelligence · Computer Science 2019-04-17 Dhruv Ramani

Replay in neural networks involves training on sequential data with memorized samples, which counteracts forgetting of previous behavior caused by non-stationarity. We present a method where these auxiliary samples are generated on the fly,…

Machine Learning · Computer Science 2020-12-15 Xu Ji , Joao Henriques , Tinne Tuytelaars , Andrea Vedaldi

Multi-Agent Experience Replay (MER) is a key component of off-policy reinforcement learning~(RL) algorithms. By remembering and reusing experiences from the past, experience replay significantly improves the stability of RL algorithms and…

Multiagent Systems · Computer Science 2023-06-02 Kailash Gogineni , Yongsheng Mei , Peng Wei , Tian Lan , Guru Venkataramani