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Objective: To enable privacy-preserving learning of high quality generative and discriminative machine learning models from distributed electronic health records. Methods and Results: We describe general and scalable strategy to build…

Cryptography and Security · Computer Science 2018-06-19 Marina Blanton , Ah Reum Kang , Subhadeep Karan , Jaroslaw Zola

In medical imaging, developing generalized segmentation models that can handle multiple organs and lesions is crucial. However, the scarcity of fully annotated datasets and strict privacy regulations present significant barriers to data…

Computer Vision and Pattern Recognition · Computer Science 2025-10-29 Pochuan Wang , Chen Shen , Masahiro Oda , Chiou-Shann Fuh , Kensaku Mori , Weichung Wang , Holger R. Roth

The continuous scaling of deep neural networks has fundamentally transformed machine learning, with larger models demonstrating improved performance across diverse tasks. This growth in model size has dramatically increased the…

Machine Learning · Computer Science 2026-01-27 Yuki Oda , Yuta Ono , Hiroshi Nakamura , Hideki Takase

Due to the rapid advancements in recent years, medical image analysis is largely dominated by deep learning (DL). However, building powerful and robust DL models requires training with large multi-party datasets. While multiple stakeholders…

Medical images used in clinical practice are heterogeneous and not the same quality as scans studied in academic research. Preprocessing breaks down in extreme cases when anatomy, artifacts, or imaging parameters are unusual or protocols…

Image and Video Processing · Electrical Eng. & Systems 2022-08-31 Mostafa Mehdipour Ghazi , Mads Nielsen

The implementation of deep learning based computer aided diagnosis systems for the classification of mammogram images can help in improving the accuracy, reliability, and cost of diagnosing patients. However, training a deep learning model…

Image and Video Processing · Electrical Eng. & Systems 2021-07-27 Saul Calderon-Ramirez , Diego Murillo-Hernandez , Kevin Rojas-Salazar , David Elizondo , Shengxiang Yang , Miguel Molina-Cabello

In this paper, we compare three privacy-preserving distributed learning techniques: federated learning, split learning, and SplitFed. We use these techniques to develop binary classification models for detecting tuberculosis from chest…

Large amount of data is often required to train and deploy useful machine learning models in industry. Smaller enterprises do not have the luxury of accessing enough data for machine learning, For privacy sensitive fields such as banking,…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-09-05 Felix Ongati , Eng. Lawrence Muchemi

Split learning is a distributed training paradigm where a neural network is partitioned between clients and a server, which allows data to remain at the client while only intermediate activations are shared. Traditional split learning…

Machine Learning · Computer Science 2026-02-10 Anower Zihad , Felix Owino , Ming Tang , Chao Huang

Federated learning (FL) has emerged with increasing popularity to collaborate distributed medical institutions for training deep networks. However, despite existing FL algorithms only allow the supervised training setting, most hospitals in…

Computer Vision and Pattern Recognition · Computer Science 2021-06-17 Quande Liu , Hongzheng Yang , Qi Dou , Pheng-Ann Heng

Distributed machine learning (ML) can bring more computational resources to bear than single-machine learning, thus enabling reductions in training time. Distributed learning partitions models and data over many machines, allowing model and…

Machine Learning · Computer Science 2022-04-20 Binhang Yuan , Cameron R. Wolfe , Chen Dun , Yuxin Tang , Anastasios Kyrillidis , Christopher M. Jermaine

Deep learning models can enable accurate and efficient disease diagnosis, but have thus far been hampered by the data scarcity present in the medical world. Automated diagnosis studies have been constrained by underpowered single-center…

Image and Video Processing · Electrical Eng. & Systems 2022-03-04 Akis Linardos , Kaisar Kushibar , Sean Walsh , Polyxeni Gkontra , Karim Lekadir

The scarcity of labeled data often impedes the application of deep learning to the segmentation of medical images. Semi-supervised learning seeks to overcome this limitation by exploiting unlabeled examples in the learning process. In this…

Computer Vision and Pattern Recognition · Computer Science 2021-06-25 Jizong Peng , Marco Pedersoli , Christian Desrosiers

This paper proposes a novel split learning framework with multiple end-systems in order to realize privacypreserving deep neural network computation. In conventional split learning frameworks, deep neural network computation is separated…

Machine Learning · Computer Science 2021-08-16 Joongheon Kim , Seunghoon Park , Soyi Jung , Seehwan Yoo

Deep learning-based segmentation techniques have shown remarkable performance in brain segmentation, yet their success hinges on the availability of extensive labeled training data. Acquiring such vast datasets, however, poses a significant…

Computer Vision and Pattern Recognition · Computer Science 2024-07-18 Jihoon Cho , Suhyun Ahn , Beomju Kim , Hyungjoon Bae , Xiaofeng Liu , Fangxu Xing , Kyungeun Lee , Georges Elfakhri , Van Wedeen , Jonghye Woo , Jinah Park

Deep learning, when integrated with a large amount of training data, has the potential to outperform machine learning in terms of high accuracy. Recently, privacy-preserving deep learning has drawn significant attention of the research…

Cryptography and Security · Computer Science 2025-04-16 Mukesh Sahani , Binanda Sengupta

Deep learning has achieved significant breakthroughs in medical imaging, but these advancements are often dependent on large, well-annotated datasets. However, obtaining such datasets poses a significant challenge, as it requires…

Computer Vision and Pattern Recognition · Computer Science 2025-04-17 Siteng Ma , Honghui Du , Yu An , Jing Wang , Qinqin Wang , Haochang Wu , Aonghus Lawlor , Ruihai Dong

Traditional supervised medical image segmentation models require large amounts of labeled data for training; however, obtaining such large-scale labeled datasets in the real world is extremely challenging. Recent semi-supervised…

Computer Vision and Pattern Recognition · Computer Science 2025-05-26 Yunyao Lu , Yihang Wu , Reem Kateb , Ahmad Chaddad

Split-Federated (SplitFed) learning is an extension of federated learning that places minimal requirements on the clients computing infrastructure, since only a small portion of the overall model is deployed on the clients hardware. In…

Computer Vision and Pattern Recognition · Computer Science 2026-01-28 Zahra Hafezi Kafshgari , Ivan V. Bajic , Parvaneh Saeedi

Machine learning in medical imaging often faces a fundamental dilemma, namely, the small sample size problem. Many recent studies suggest using multi-domain data pooled from different acquisition sites/centers to improve statistical power.…

Computer Vision and Pattern Recognition · Computer Science 2024-07-09 Hao Guan , Pew-Thian Yap , Andrea Bozoki , Mingxia Liu