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Clinical notes are a rich source of information about patient state. However, using them to predict clinical events with machine learning models is challenging. They are very high dimensional, sparse and have complex structure. Furthermore,…

Machine Learning · Statistics 2018-08-20 Sebastien Dubois , Nathanael Romano , David C. Kale , Nigam Shah , Kenneth Jung

Clinical notes contain information about patients that goes beyond structured data like lab values and medications. However, clinical notes have been underused relative to structured data, because notes are high-dimensional and sparse. This…

Computation and Language · Computer Science 2020-12-01 Kexin Huang , Jaan Altosaar , Rajesh Ranganath

Large pre-trained language models (LMs) have been widely adopted in biomedical and clinical domains, introducing many powerful LMs such as bio-lm and BioELECTRA. However, the applicability of these methods to real clinical use cases is…

Computation and Language · Computer Science 2022-11-16 Samuel Cahyawijaya , Bryan Wilie , Holy Lovenia , Huan Zhong , MingQian Zhong , Yuk-Yu Nancy Ip , Pascale Fung

Clinical notes contain a large amount of clinically valuable information that is ignored in many clinical decision support systems due to the difficulty that comes with mining that information. Recent work has found success leveraging deep…

Machine Learning · Computer Science 2019-11-13 Justin R. Lovelace , Nathan C. Hurley , Adrian D. Haimovich , Bobak J. Mortazavi

Recent advances in large language models have led to renewed interest in natural language processing in healthcare using the free text of clinical notes. One distinguishing characteristic of clinical notes is their long time span over…

Computation and Language · Computer Science 2023-07-17 Hongyi Zheng , Yixin Zhu , Lavender Yao Jiang , Kyunghyun Cho , Eric Karl Oermann

Clinical notes contain valuable, context-rich information, but their unstructured format introduces several challenges, including unintended biases (e.g., gender or racial bias), and poor generalization across clinical settings (e.g.,…

Computation and Language · Computer Science 2025-11-18 Karthikeyan K , Raghuveer Thirukovalluru , David Carlson

Clinical notes contain an extensive record of a patient's health status, such as smoking status or the presence of heart conditions. However, this detail is not replicated within the structured data of electronic health systems.…

Computation and Language · Computer Science 2020-09-18 Andriy Mulyar , Elliot Schumacher , Masoud Rouhizadeh , Mark Dredze

Clinical notes are text documents that are created by clinicians for each patient encounter. They are typically accompanied by medical codes, which describe the diagnosis and treatment. Annotating these codes is labor intensive and error…

Computation and Language · Computer Science 2018-04-18 James Mullenbach , Sarah Wiegreffe , Jon Duke , Jimeng Sun , Jacob Eisenstein

Clinical notes in electronic health records contain highly heterogeneous writing styles, including non-standard terminology or abbreviations. Using these notes in predictive modeling has traditionally required preprocessing (e.g. taking…

Machine Learning · Computer Science 2019-11-18 Jonas Kemp , Alvin Rajkomar , Andrew M. Dai

Diagnosis of a clinical condition is a challenging task, which often requires significant medical investigation. Previous work related to diagnostic inferencing problems mostly consider multivariate observational data (e.g. physiological…

Computation and Language · Computer Science 2017-01-05 Aaditya Prakash , Siyuan Zhao , Sadid A. Hasan , Vivek Datla , Kathy Lee , Ashequl Qadir , Joey Liu , Oladimeji Farri

Clinical notes in Electronic Health Records (EHRs) capture rich temporal information on events, clinician reasoning, and lifestyle factors often missing from structured data. Leveraging them for predictive modeling can be impactful for…

Computation and Language · Computer Science 2026-05-08 Rochana Chaturvedi , Yue Zhou , Andrew D. Boyd , Brian T. Layden , Mudassir Rashid , Lu Cheng , Ali Cinar , Barbara Di Eugenio

Effective clinical history taking is a foundational yet underexplored component of clinical reasoning. While large language models (LLMs) have shown promise on static benchmarks, they often fall short in dynamic, multi-turn diagnostic…

Computation and Language · Computer Science 2026-01-30 Yang Zhou , Zhenting Sheng , Mingrui Tan , Yuting Song , Jun Zhou , Yu Heng Kwan , Lian Leng Low , Yang Bai , Yong Liu

Clinical case reports encode temporal patient trajectories that are often underexploited by traditional machine learning methods relying on structured data. In this work, we introduce the forecasting problem from textual time series, where…

Computation and Language · Computer Science 2025-12-30 Shahriar Noroozizadeh , Sayantan Kumar , Jeremy C. Weiss

The clinical notes are usually typed into the system by physicians. They are typically required to be marked by standard medical codes, and each code represents a diagnosis or medical treatment procedure. Annotating these notes is time…

Machine Learning · Computer Science 2023-05-10 Guodong Liu

Clinical notes are often stored in unstructured or semi-structured formats after extraction from electronic medical record (EMR) systems, which complicates their use for secondary analysis and downstream clinical applications. Reliable…

Computation and Language · Computer Science 2025-12-30 Risha Surana , Adrian Law , Sunwoo Kim , Rishab Sridhar , Angxiao Han , Peiyu Hong

This study demonstrates the effectiveness of XLNet, a transformer-based language model, for annotating argumentative elements in persuasive essays. XLNet's architecture incorporates a recurrent mechanism that allows it to model long-term…

Computation and Language · Computer Science 2023-11-13 Christopher Ormerod , Amy Burkhardt , Mackenzie Young , Sue Lottridge

Electronic health records (EHRs) are designed to synthesize diverse data types, including unstructured clinical notes, structured lab tests, and time-series visit data. Physicians draw on these multimodal and temporal sources of EHR data to…

Unstructured clinical text in EHRs contains crucial information for applications including decision support, trial matching, and retrospective research. Recent work has applied BERT-based models to clinical information extraction and text…

Computation and Language · Computer Science 2020-11-13 Kexin Huang , Sankeerth Garapati , Alexander S. Rich

Early detection of preventable diseases is important for better disease management, improved inter-ventions, and more efficient health-care resource allocation. Various machine learning approacheshave been developed to utilize information…

Machine Learning · Computer Science 2018-08-16 Jingshu Liu , Zachariah Zhang , Narges Razavian

Assisted text input techniques can save time and effort and improve text quality. In this paper, we investigate how grounded and conditional extensions to standard neural language models can bring improvements in the tasks of word…

Computation and Language · Computer Science 2016-10-21 Georgios P. Spithourakis , Steffen E. Petersen , Sebastian Riedel
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