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Dose-response prediction in cancer is an active application field in machine learning. Using large libraries of \textit{in-vitro} drug sensitivity screens, the goal is to develop accurate predictive models that can be used to guide…

Quantitative Methods · Quantitative Biology 2024-07-02 Leiv Rønneberg , Vidhi Lalchand , Paul D. W. Kirk

We consider the estimation of large covariance and precision matrices from high-dimensional sub-Gaussian or heavier-tailed observations with slowly decaying temporal dependence. The temporal dependence is allowed to be long-range so with…

Statistics Theory · Mathematics 2019-12-23 Hai Shu , Bin Nan

The task of distribution generalization concerns making reliable prediction of a response in unseen environments. The structural causal models are shown to be useful to model distribution changes through intervention. Motivated by the…

Methodology · Statistics 2022-06-14 Kang Du , Yu Xiang

Real-world signals typically span across multiple dimensions, that is, they naturally reside on multi-way data structures referred to as tensors. In contrast to standard ``flat-view'' multivariate matrix models which are agnostic to data…

Signal Processing · Electrical Eng. & Systems 2019-12-04 Bruno Scalzo Dees , Anh-Huy Phan , Danilo P. Mandic

Generative AI has achieved remarkable empirical success, but from the perspective of statistics it often remains opaque: its predictions may be accurate, yet the underlying mechanism is difficult to interpret, analyze, and trust. This book…

Machine Learning · Statistics 2026-03-11 Shinto Eguchi

The modality is important topic for modelling. Using parametric models is an efficient way when real data set shows trimodality. In this paper we propose a new class of trimodal probability distributions, that is, probability distributions…

Methodology · Statistics 2022-04-08 Roberto Vila , Victor Serra , Mehmet N. Çankaya , Felipe Quintino

Graphical models have become a very popular tool for representing dependencies within a large set of variables and are key for representing causal structures. We provide results for uniform inference on high-dimensional graphical models…

Methodology · Statistics 2018-12-04 Sven Klaassen , Jannis Kück , Martin Spindler , Victor Chernozhukov

The Riemannian geometry of covariance matrices has been essential to several successful applications, in computer vision, biomedical signal and image processing, and radar data processing. For these applications, an important ongoing…

Statistics Theory · Mathematics 2017-05-15 Salem Said , Hatem Hajri , Lionel Bombrun , Baba C. Vemuri

When inferring parameters from a Gaussian-distributed data set by computing a likelihood, a covariance matrix is needed that describes the data errors and their correlations. If the covariance matrix is not known a priori, it may be…

Cosmology and Nongalactic Astrophysics · Physics 2016-01-27 Elena Sellentin , Alan F. Heavens

This work considers estimation and forecasting in a multivariate, possibly high-dimensional count time series model constructed from a transformation of a latent Gaussian dynamic factor series. The estimation of the latent model parameters…

Methodology · Statistics 2025-04-07 Younghoon Kim , Marie-Christine Düker , Zachary F. Fisher , Vladas Pipiras

Advances in neural variational inference have facilitated the learning of powerful directed graphical models with continuous latent variables, such as variational autoencoders. The hope is that such models will learn to represent rich,…

Computation and Language · Computer Science 2017-09-26 Iulian V. Serban , Alexander G. Ororbia , Joelle Pineau , Aaron Courville

In the principles-and-parameters framework, the structural features of languages depend on parameters that may be toggled on or off, with a single parameter often dictating the status of multiple features. The implied covariance between…

Computation and Language · Computer Science 2019-05-16 Johannes Bjerva , Yova Kementchedjhieva , Ryan Cotterell , Isabelle Augenstein

This paper aims to examine the characteristics of the posterior distribution of covariance/precision matrices in a "large $p$, large $n$" scenario, where $p$ represents the number of variables and $n$ is the sample size. Our analysis…

Statistics Theory · Mathematics 2026-02-02 Partha Sarkar , Kshitij Khare , Malay Ghosh , Matt P. Wand

The assumption of Gaussian or Gaussian mixture data has been extensively exploited in a long series of precise performance analyses of machine learning (ML) methods, on large datasets having comparably numerous samples and features. To…

Machine Learning · Statistics 2025-03-14 Xiaoyi Mai , Zhenyu Liao

While a typical supervised learning framework assumes that the inputs and the outputs are measured at the same levels of granularity, many applications, including global mapping of disease, only have access to outputs at a much coarser…

We revisit the replica method for analyzing inference and learning in parametric models, considering situations where the data-generating distribution is unknown or analytically intractable. Instead of assuming idealized distributions to…

Disordered Systems and Neural Networks · Physics 2025-11-17 Takashi Takahashi

Distributional semantic models provide vector representations for words by gathering co-occurrence frequencies from corpora of text. Compositional distributional models extend these from words to phrases and sentences. In categorical…

Computation and Language · Computer Science 2018-10-10 Esma Balkir , Dimitri Kartsaklis , Mehrnoosh Sadrzadeh

According to the distributional inclusion hypothesis, entailment between words can be measured via the feature inclusions of their distributional vectors. In recent work, we showed how this hypothesis can be extended from words to phrases…

Computation and Language · Computer Science 2016-10-17 Dimitri Kartsaklis , Mehrnoosh Sadrzadeh

We consider a model for multivariate data with heavy-tailed marginal distributions and a Gaussian dependence structure. The different marginals in the model are allowed to have non-identical tail behavior in contrast to most popular…

Methodology · Statistics 2023-05-23 Bikramjit Das

Several techniques to map various types of components, such as words, attributes, and images, into the embedded space have been studied. Most of them estimate the embedded representation of target entity as a point in the projective space.…

Computer Vision and Pattern Recognition · Computer Science 2022-11-09 Ryotaro Shimizu , Masanari Kimura , Masayuki Goto