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Drug repurposing plays a critical role in accelerating treatment discovery, especially for complex and rare diseases. Biomedical knowledge graphs (KGs), which encode rich clinical associations, have been widely adopted to support this task.…

Computation and Language · Computer Science 2025-10-15 Chengrui Xiang , Tengfei Ma , Xiangzheng Fu , Yiping Liu , Bosheng Song , Xiangxiang Zeng

Causal relation extraction of biomedical entities is one of the most complex tasks in biomedical text mining, which involves two kinds of information: entity relations and entity functions. One feasible approach is to take relation…

Computation and Language · Computer Science 2022-08-03 Dongling Li , Pengchao Wu , Yuehu Dong , Jinghang Gu , Longhua Qian , Guodong Zhou

Successful biomedical relation extraction can provide evidence to researchers and clinicians about possible unknown associations between biomedical entities, advancing the current knowledge we have about those entities and their inherent…

Information Retrieval · Computer Science 2020-04-22 Diana Sousa , Francisco M. Couto

We compare the use of LSTM-based and CNN-based character-level word embeddings in BiLSTM-CRF models to approach chemical and disease named entity recognition (NER) tasks. Empirical results over the BioCreative V CDR corpus show that the use…

Computation and Language · Computer Science 2018-08-28 Zenan Zhai , Dat Quoc Nguyen , Karin Verspoor

Knowledge Bases (KBs) require constant up-dating to reflect changes to the world they represent. For general purpose KBs, this is often done through Relation Extraction (RE), the task of predicting KB relations expressed in text mentioning…

Computation and Language · Computer Science 2019-05-13 Peng Xu , Denilson Barbosa

In this paper, we investigate how semantic relations between concepts extracted from medical documents can be employed to improve the retrieval of medical literature. Semantic relations explicitly represent relatedness between concepts and…

Information Retrieval · Computer Science 2019-05-06 Maristella Agosti , Giorgio Maria Di Nunzio , Stefano Marchesin , Gianmaria Silvello

Automated relation extraction (RE) from biomedical literature is critical for many downstream text mining applications in both research and real-world settings. However, most existing benchmarking datasets for bio-medical RE only focus on…

Computation and Language · Computer Science 2022-07-20 Ling Luo , Po-Ting Lai , Chih-Hsuan Wei , Cecilia N Arighi , Zhiyong Lu

The embedding of Biomedical Knowledge Graphs (BKGs) generates robust representations, valuable for a variety of artificial intelligence applications, including predicting drug combinations and reasoning disease-drug relationships.…

Databases · Computer Science 2023-10-17 Zhiguang Fan , Yuedong Yang , Mingyuan Xu , Hongming Chen

Biomedical event extraction is critical in understanding biomolecular interactions described in scientific corpus. One of the main challenges is to identify nested structured events that are associated with non-indicative trigger words. We…

Computation and Language · Computer Science 2020-10-13 Kung-Hsiang Huang , Mu Yang , Nanyun Peng

In this study, a novel method for extracting named entities and relations from unstructured text based on the table representation is presented. By using contextualized word embeddings, the proposed method computes representations for…

Computation and Language · Computer Science 2022-01-28 Youmi Ma , Tatsuya Hiraoka , Naoaki Okazaki

We present an analysis of the problem of identifying biological context and associating it with biochemical events in biomedical texts. This constitutes a non-trivial, inter-sentential relation extraction task. We focus on biological…

Computation and Language · Computer Science 2018-12-18 Enrique Noriega-Atala , Paul D. Hein , Shraddha S. Thumsi , Zechy Wong , Xia Wang , Clayton T. Morrison

Background : Knowledge is evolving over time, often as a result of new discoveries or changes in the adopted methods of reasoning. Also, new facts or evidence may become available, leading to new understandings of complex phenomena. This is…

Computation and Language · Computer Science 2023-04-24 Ayoub Harnoune , Maryem Rhanoui , Mounia Mikram , Siham Yousfi , Zineb Elkaimbillah , Bouchra El Asri

The objective of our work is to demonstrate the feasibility of utilizing deep learning models to extract safety signals related to the use of dietary supplements (DS) in clinical text. Two tasks were performed in this study. For the named…

Information Retrieval · Computer Science 2020-11-24 Yadan Fan , Sicheng Zhou , Yifan Li , Rui Zhang

Document-level relation extraction (RE), which requires reasoning on multiple entities in different sentences to identify complex inter-sentence relations, is more challenging than sentence-level RE. To extract the complex inter-sentence…

Computation and Language · Computer Science 2022-04-04 Liang Zhang , Yidong Cheng

Identifying the relations between chemicals and proteins is an important text mining task. BioCreative VII track 1 DrugProt task aims to promote the development and evaluation of systems that can automatically detect relations between…

Computation and Language · Computer Science 2021-12-07 Mehmet Efruz Karabulut , K. Vijay-Shanker , Yifan Peng

Answer selection, which is involved in many natural language processing applications such as dialog systems and question answering (QA), is an important yet challenging task in practice, since conventional methods typically suffer from the…

Computation and Language · Computer Science 2021-04-13 Yang Deng , Yuexiang Xie , Yaliang Li , Min Yang , Wai Lam , Ying Shen

The COVID-19 pandemic has spawned a diverse body of scientific literature that is challenging to navigate, stimulating interest in automated tools to help find useful knowledge. We pursue the construction of a knowledge base (KB) of…

Computation and Language · Computer Science 2021-04-20 Tom Hope , Aida Amini , David Wadden , Madeleine van Zuylen , Sravanthi Parasa , Eric Horvitz , Daniel Weld , Roy Schwartz , Hannaneh Hajishirzi

Constructing large-scaled medical knowledge graphs can significantly boost healthcare applications for medical surveillance, bring much attention from recent research. An essential step in constructing large-scale MKG is extracting…

Computer Vision and Pattern Recognition · Computer Science 2021-10-27 Jialun Wu , Yang Liu , Zeyu Gao , Tieliang Gong , Chunbao Wang , Chen Li

Adverse drug events (ADEs) are an important aspect of drug safety. Various texts such as biomedical literature, drug reviews, and user posts on social media and medical forums contain a wealth of information about ADEs. Recent studies have…

Computation and Language · Computer Science 2024-05-21 Shaoxiong Ji , Ya Gao , Pekka Marttinen

Document-level relation extraction (DocRE) is an active area of research in natural language processing (NLP) concerned with identifying and extracting relationships between entities beyond sentence boundaries. Compared to the more…